Gene Information

Name : umuC (Ent638_2212)
Accession : YP_001176938.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : 2.7.7.7
Position : 2403234 - 2404502 bp
Length : 1269 bp
Strand : -
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTTGCGCTCTGCGATGTGAATTCATTTTACGCATCATGCGAGACGGTATTCAGACCTGACCTGAGGGGGCGGCCAGT
GGTCGTTCTCTCGAACAATGATGGCTGTGTAATTGCAAGATCGGCCGAGGCCAAGACTGCAGGAATTACCATGGGTGATC
CCTTCTTCAAGCAAAAGGAATTGTTCCGGCGCGCTGGCGTTGTTTGCTTCAGCAGTAACTACGAGCTCTACGCTGACATG
TCCAACAGGGTGATGACAACGCTGGAAGAAATGAGCCCCCGCGTCGAAATTTACAGTATTGACGAAGCATTTTGTGACCT
GACCGGTGTACGGAACTGTCGGGACCTGACTGATTTTGGTAAAGAGATCCGCGCGACGGTGCTCAAGCGGACGCATCTTA
CCGTCGGCGTTGGCATTGCACAGACTAAAACCCTGGCAAAACTTGCAAACCACGCCGCGAAGAAATGGCAGCGGCAGACG
GGCGGGGTAGTTGACCTGTCTAACATCGATCGCCAGCGCCGTCTGCTTGCGCTAGTACCTGTCGAGGATGTCTGGGGCGT
GGGTCGGCGCATCAGCAAGAAACTCAATGCCATGGGCATCAAAACTGCGCTGGACCTCTCAGAACAGAGCACCTGGATTA
TCCGTAAACACTTTAATGTTGTGCTCGAGCGAACGGTACGCGAGCTGCGCGGTGAACCTTGTCTTGATCTGGAAGAGTTT
GCACCAGCAAAGCAGGAAATTGTCTGCAGCCGTTCCTTTGGCGAACGGGTTACAGAATACGAACAGATGCGCCAGGCGAT
ATGCTCTTATGCTGCGCGTGGCGCAGAGAAACTTCGCGGAGAGCATCAGTATTGTCGCTTTATTTCCGCGTTCGTTAAGA
CTTCTCCCTTTGCGCTCAATGAGCCGTATTACGGTAACAGCTCCTCAGTAAAACTGCTGACGCCCACGCATGACAGCCGG
GACATTATCAACGCTGCGGTAAAGTGTCTGGAAGCCATCTGGAAGGATGGTCACCGGTACCAGAAGGCGGGGATCATGCT
TGGTGACTTCTTCAGTCAGGGCGTGGCTCAATTGAACCTGTTCGACGAGAACGCACCTCGCGCCGGTAGCGATAGGCTTA
TGGAGGTGCTGGACCATTTGAATGCAAAAGATGGAAAGGGAACGCTCTACTTCGCCGGGCAGGGCATACAGCAGCAGTGG
CAGATGAAGCGAGAGATGCTCTCGCCGCGATACACTACACGTTTTTGTGACCTGATTATTGTAAAATAG

Protein sequence :
MFALCDVNSFYASCETVFRPDLRGRPVVVLSNNDGCVIARSAEAKTAGITMGDPFFKQKELFRRAGVVCFSSNYELYADM
SNRVMTTLEEMSPRVEIYSIDEAFCDLTGVRNCRDLTDFGKEIRATVLKRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
GGVVDLSNIDRQRRLLALVPVEDVWGVGRRISKKLNAMGIKTALDLSEQSTWIIRKHFNVVLERTVRELRGEPCLDLEEF
APAKQEIVCSRSFGERVTEYEQMRQAICSYAARGAEKLRGEHQYCRFISAFVKTSPFALNEPYYGNSSSVKLLTPTHDSR
DIINAAVKCLEAIWKDGHRYQKAGIMLGDFFSQGVAQLNLFDENAPRAGSDRLMEVLDHLNAKDGKGTLYFAGQGIQQQW
QMKREMLSPRYTTRFCDLIIVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 2e-126 63
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 2e-126 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 1e-91 49
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 5e-78 49