Gene Information

Name : tpx (Ent638_2151)
Accession : YP_001176877.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.5
Position : 2338695 - 2339201 bp
Length : 507 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGTCACAACTCGTTCATTTTCAGGGCAACCCAGTTACTGTTGCAGGCTCTATTCCACAGGCTGGCAGCAAAGCGCAGGC
TTTTACCCTCGTAGCGAAAGACCTGTCTGATGTAACGTTGGGCCAGTTTGCTGGCAAACGCAAAGTTCTGAATATTTTCC
CAAGCATTGATACCGGCGTTTGTGCAGCTTCCGTGCGCAAATTTAACCAGTTGGCGACTGAAATGGACAACACCGTGGTG
CTGTGCATTTCCGCTGACCTGCCGTTTGCCCAGTCCCGTTTCTGCGGTGCAGAAGGTTTGAGCAACGTCATCACCCTTTC
TACCCTGCGTAGCCAGGATTTTGTCGAAAACTACGGCGTAGGGATCGCAGAAGGCGCTCTAAAAGGCCTGACCGCGCGTG
CGGTACTGGTCATCGACGAAAACGACACCGTTGTTTTCAGTGAACTGGTTAACGAGATCACCAACGAACCGGATTACACT
GCAGCGCTGGAAGTCTTAAAAGCGTAA

Protein sequence : 
MSQLVHFQGNPVTVAGSIPQAGSKAQAFTLVAKDLSDVTLGQFAGKRKVLNIFPSIDTGVCAASVRKFNQLATEMDNTVV
LCISADLPFAQSRFCGAEGLSNVITLSTLRSQDFVENYGVGIAEGALKGLTARAVLVIDENDTVVFSELVNEITNEPDYT
AALEVLKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 5e-36 51
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 3e-36 51
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 4e-36 51
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 2e-36 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001176877.1 thiol peroxidase VFG0087 Protein 7e-37 51