Gene Information

Name : Ent638_1769 (Ent638_1769)
Accession : YP_001176499.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 1922978 - 1924123 bp
Length : 1146 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: plu:plu0523 unnamed protein product; similar to cystathionine gamma-lyase

DNA sequence :
ATGAAAACATTGGCCACGTTAAGCGTCCACAGCGGCGAGTTTCACGATCAGCACGGCGCAGTGATGCCGCCGATTTATGC
CACCTCGACGTTTGCGCAACCCTCGCCCGGCGAGCATACCGGATACGAATATTCCCGCAGCGGTAATCCGACTCGTCATG
CGCTGGAAACCGCCATCGCTGAACTGGAGAGCGGTACACGCGGATTTGCGTTTGCATCAGGACTGGCGGCCATCGCCACC
GTGCTGGAGCTGCTGGATAAAGACAGCCATATCGTCGCGATTGACGACGTATACGGCGGAACGTATCGCCTGATCGAAAA
TGTGCGCAAACGCAGTACAGGGTTACAGGTGAGCTGGGTGAAGCCCGGCGATCTTGCCGCGCTGGACGCGGCCATCCGCC
CCGAGACCAAAATGATTTGGGTGGAAACGCCGACCAACCCCCTGCTGAAACTGGCCGACCTCGCGGGGATCGCCGCTATC
GCCCGTCGCCATAACATTATTAGCGTCGCGGATAACACCTTTGCATCGCCGGTTATTCATCGTCCGCTGGAATTTGGTTT
TGATATCGTGGTGCATTCCGCGACGAAATACCTCAATGGCCACTCGGACGTAGTCGCAGGGCTGGCGGTGGTCGGCAGTA
ATAGCCCTTTGGCTGAAAAGCTGGGCTATTTGCAAAACGCGATTGGCGGCGTCCTCGATCCGTTCAGCAGTTTCCTGACC
TTACGCGGGATTCGTACTCTCGCCTTGCGCGTGGAAAAGCACAGTGCGAATGCGCTGGCGATTGCGCAACGACTTGAGCA
GCATCCACAAATTGAAAAAGTCTGGTTCCCGTGGCTGGAATCTCATCCCCATTATCAGCTGGCCCGCACCCAGATGGCAC
TGCCCGGCGGGATGATTTCGGTGGTGGTGAAAGGCGATGCGCAACGGGCAACGGACATCATCCGCAAGCTGAAGCTGTTT
ACGCTAGCCGAAAGCCTGGGCGGCGTAGAAAGCCTTGTTAGCCAGCCTTACAGCATGACGCACGCGTCCATTCCCCTCGA
ACAGCGGCTGGCAAACGGTATTGTTCCGCAACTGATTCGCCTGTCTGTCGGAATAGAGGATGCGAGCGACCTGATTGCCG
ACCTGGAGCAGGCGCTGACAATTTAA

Protein sequence :
MKTLATLSVHSGEFHDQHGAVMPPIYATSTFAQPSPGEHTGYEYSRSGNPTRHALETAIAELESGTRGFAFASGLAAIAT
VLELLDKDSHIVAIDDVYGGTYRLIENVRKRSTGLQVSWVKPGDLAALDAAIRPETKMIWVETPTNPLLKLADLAGIAAI
ARRHNIISVADNTFASPVIHRPLEFGFDIVVHSATKYLNGHSDVVAGLAVVGSNSPLAEKLGYLQNAIGGVLDPFSSFLT
LRGIRTLALRVEKHSANALAIAQRLEQHPQIEKVWFPWLESHPHYQLARTQMALPGGMISVVVKGDAQRATDIIRKLKLF
TLAESLGGVESLVSQPYSMTHASIPLEQRLANGIVPQLIRLSVGIEDASDLIADLEQALTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-80 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-81 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-58 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ent638_1769 YP_001176499.1 cystathionine gamma-synthase BAC0207 Protein 4e-67 44