Gene Information

Name : Ent638_1437 (Ent638_1437)
Accession : YP_001176168.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1583656 - 1584402 bp
Length : 747 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTTGTCGTCATTATTCCGGCGCGTTTTGCCTCCACGCGTTTACCAGGCAAGCCGCTGGTGGATATTAATGGCAA
ACCGATGATTGTCCATGTGCTTGAAAGAGCACGTGAGTCAGGTGCCGATCGCGTGATTGTTGCCACGGATCACGAAGACG
TTGCCCGTGCCGTCGAAGCGGCCGGTGGCGAAGTATGCATGACTCGTGCCGATCATCAGTCCGGCACGGAAAGACTGGCC
GAAGTCGTCGAAAAATGTGGTTTTAGCGATGACACCGTTATCGTTAACGTGCAGGGCGATGAACCGATGATTCCGGCGGC
TATTATTCGTCAGGTCGCGGAAAACCTCGCGCAGCGTCAGGTGGGAATGGCCACGCTTGCCGTGCCCATTCATCATGCTG
AAGAAGCGTTTAATCCGAACGCGGTTAAAGTGGTGATGGATGCTGAAGGCTACGCGCTCTATTTCTCCCGCGCGGCTATT
CCGTGGGATCGCGACCGTTTTGCCGCCTCTCAAGAGGTGATTGGCGACACGTTCCTGCGACACTTGGGCATTTATGGCTA
TCGTGCAGGCTTTATCCGTCGCTATGTAACCTGGGCGCCAAGTCCGCTGGAGCATATCGAAATGCTCGAACAGCTGCGTG
TGCTCTGGTATGGCGAAAAAATCCACGTTGCGGTTGCCCAGGAAGTTCCTGGAACGGGCGTTGATACACCCGAAGATCTT
GAACGCGTGCGTGCTGAACTGCATTAA

Protein sequence :
MSFVVIIPARFASTRLPGKPLVDINGKPMIVHVLERARESGADRVIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCGFSDDTVIVNVQGDEPMIPAAIIRQVAENLAQRQVGMATLAVPIHHAEEAFNPNAVKVVMDAEGYALYFSRAAI
PWDRDRFAASQEVIGDTFLRHLGIYGYRAGFIRRYVTWAPSPLEHIEMLEQLRVLWYGEKIHVAVAQEVPGTGVDTPEDL
ERVRAELH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 8e-34 44
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-33 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-33 44