Gene Information

Name : Ent638_1417 (Ent638_1417)
Accession : YP_001176148.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1557186 - 1558478 bp
Length : 1293 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTCGATCCCAATCTTTTGCGTAACGAGCCAGACGCAGTCGCTGAAAAACTGGCACGCCGGGGCTTTAAGCTGGATGT
AGATAAGCTGCGCGCTCTTGAAGAGCGTCGTAAAGTTCTGCAGGTACAAACTGAAAATCTGCAGGCTGAGCGTAATTCTC
GATCGAAATCCATTGGCCAGGCGAAAGCACGCGGGGAAGATATTGAGCCATTGCGTCTGGAAGTGAACAAACTGGGCGAA
GAACTGGATCAGGCGAAAACTGAGCTGGAACTTCTCCTGGCTGAAATTCGTGATATTGCACTGGCGATCCCGAACACACC
TGATGATAGCGTTCCTGTCGGTAAAGACGAAAACGACAACGTTGAAGTAAAACGCTGGGGCACGCCTCGCGAATTCGACT
TTGAGGTTCGCGATCACGTGACGCTGGGCGAAATGCACGCCGGTCTGGACTTTGCGGCCGCGGTGAAATTGACCGGCGCT
CGCTTTGTCGTGATGAAAGGTCAAATTGCACATCTGCATCGCGCATTGGCGCAATTCATGCTGGATCTTCACACCGAGCA
ACACGGCTACAGCGAAACCTACGTCCCGTATCTGGTAAACCACGATACGCTGTATGGTACTGGCCAGTTGCCTAAGTTTG
CCGGCGATCTGTTCCATACGCGTCCGCTTGACGAAGAAGCCGAGAGCAGCAACTATGCACTGATCCCAACGGCTGAAGTG
CCGCTGACTAACCTCGTGCGTGACGAAATTATCGACGAAGACGATCTGCCTATCAAACTGACCGCACATTCTCCATGCTT
CCGTTCCGAAGCGGGATCTTACGGTCGTGACACACGCGGTCTGATCCGTATGCACCAGTTTGACAAAGTTGAGATGGTAC
AGATCGTTCGCCCGGAAGTGTCGATGGATGCACTGGAAGAAATGACCGGCCATGCTGAGAAGGTTCTGGAGCTGTTAGGC
TTACCATATCGTCGTATGGCGCTTTGCACAGGCGACATGGGCTTTGGCGCAACCAAAACGTTCGACTTGGAAGTTTGGGT
TCCTGCGCAGAACACCTACCGCGAAATCTCTTCTTGCTCGAACGTGGGCGATTTCCAGGCGCGTCGTATGCAAGCGCGTT
GCCGCACCAAGGCTGACAAGAAGACCCGTTTGGTTCACACGCTAAATGGTTCTGGTTTGGCTGTCGGCCGCGCATTGGTT
GCGGTGATGGAAAACTACCAGCAGGCAGATGGCCGTATCGAAATTCCTGAAGTGCTGCGCCCCTATATGAAAGGCCAGCA
ATACATCGGTTAA

Protein sequence :
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLRALEERRKVLQVQTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGE
ELDQAKTELELLLAEIRDIALAIPNTPDDSVPVGKDENDNVEVKRWGTPREFDFEVRDHVTLGEMHAGLDFAAAVKLTGA
RFVVMKGQIAHLHRALAQFMLDLHTEQHGYSETYVPYLVNHDTLYGTGQLPKFAGDLFHTRPLDEEAESSNYALIPTAEV
PLTNLVRDEIIDEDDLPIKLTAHSPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEVSMDALEEMTGHAEKVLELLG
LPYRRMALCTGDMGFGATKTFDLEVWVPAQNTYREISSCSNVGDFQARRMQARCRTKADKKTRLVHTLNGSGLAVGRALV
AVMENYQQADGRIEIPEVLRPYMKGQQYIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 3e-108 56