Gene Information

Name : Ent638_0143 (Ent638_0143)
Accession : YP_001174884.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Virulence
Product : lactaldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.22
Position : 162879 - 164417 bp
Length : 1539 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: stm:STM3680 aldehyde dehydrogenase B

DNA sequence :
ATGACGAATAATCCTCCCTCAACGCGTTTGCAGCCTGGCGAGTATGGTTATCCCCTCAAGTTAAAACCCCGGTACGACAA
TTTCATAGGCGGCGGCTGGGTTGCTCCCGTCGACGGCGAGTATTACTCGAACCTGACGCCTGTCACTGGGCAACCGCTGT
GCGAAATCGCCAGCTCCGGCAAAAAAGATATCGATCTGGCACTGGATGCGGCGCATAAAGCGAAAGAGAAATGGGGGCAC
ACCTCGGTTCAGGACCGAGCCGCCATTCTGTTGAAAATTGCCGATCGGATGGAGCAAAACCTGGAGCTGCTGGCAGCGGC
TGAAACCTGGGATAACGGCAAACCGATCCGCGAAACCACCGGCGCTGACGTACCACTGGCTATCGACCACTTCCGTTATT
TTGCCTCCTGTATTCGCGCTCAGGAAGGGGGAATCAGCGAGGTGGACAGTGAAACCGTTGCCTACCATTTTCACGAGCCG
CTGGGTGTCGTGGGGCAAATTATTCCATGGAACTTCCCGCTGCTGATGGCGAGCTGGAAAATGGCTCCCGCGCTGGCGGC
GGGCAACTGCGTGATCCTCAAACCGGCACGCTTAACCCCGCTGTCCGTATTGCTGCTGATGGAAATCATTGGCGACCTGG
TTCCGCCGGGGGTGATTAACGTTGTGAACGGGGCAGGCGGCGAAATCGGTGAATATCTGGCGACCTCGAAGCGTATCGCG
AAAGTCGCGTTTACCGGCTCCACGGAAGTGGGCCAGCAGATCATGCAGTATGCGACCCAAAATATCATTCCAGTCACGCT
GGAGTTGGGCGGCAAATCGCCGAACATTTTCTTTGCCGATGTGATGGATGAAGAGGATGCTTTCTTCGACAAAGCGCTGG
AAGGGTTTGCGCTGTTTGCCTTTAACCAGGGCGAGGTTTGCACCTGTCCAAGCCGAGCGCTGGTGCAGGAATCCATTTAT
GAACGCTTCATGGAGCGGGCTATTCGTCGGGTGGAATCCATCCGCAGTGGTAATCCGCTGGACAGCGTCACGCAGATGGG
CGCACAGGTTTCGCAGGGGCAGCTGGAGACTATCCTCAATTACATCGATATCGGTAAGAAAGAGGGCGCAGATGTTCTGA
CCGGCGGGCGTCGAAAAATGCTCGAAGGCGATCTGAAAGATGGCTTTTACCTTGAGCCGACCATTCTGTTTGGCAAAAAT
GATATGCGCGTTTTCCAGGAGGAAATCTTCGGTCCGGTGCTGGCGGTGACAACGTTTAAAACCATGGAGGAAGCACTGGA
GTTGGCCAACGATACGCAATATGGCCTCGGGGCGGGTGTCTGGAGCCGCAACGGTAATCTGGCGTACAAAATGGGGCGCG
GAATTCAGGCCGGACGCGTCTGGACAAACTGCTATCACGCCTATCCGGCCCATGCCGCGTTTGGTGGATATAAGCAGTCG
GGGATTGGGCGCGAAACGCACAAGATGATGCTGAACCATTACCAGCAAACGAAATGCTTGCTGGTCAGCTATTCGGATAA
ACCGTTGGGTTTATTCTAA

Protein sequence :
MTNNPPSTRLQPGEYGYPLKLKPRYDNFIGGGWVAPVDGEYYSNLTPVTGQPLCEIASSGKKDIDLALDAAHKAKEKWGH
TSVQDRAAILLKIADRMEQNLELLAAAETWDNGKPIRETTGADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
LGVVGQIIPWNFPLLMASWKMAPALAAGNCVILKPARLTPLSVLLLMEIIGDLVPPGVINVVNGAGGEIGEYLATSKRIA
KVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNIFFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIY
ERFMERAIRRVESIRSGNPLDSVTQMGAQVSQGQLETILNYIDIGKKEGADVLTGGRRKMLEGDLKDGFYLEPTILFGKN
DMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYKMGRGIQAGRVWTNCYHAYPAHAAFGGYKQS
GIGRETHKMMLNHYQQTKCLLVSYSDKPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-153 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-158 64
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-158 64
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-158 64
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-158 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Ent638_0143 YP_001174884.1 lactaldehyde dehydrogenase VFG0082 Protein 5e-154 64