Gene Information

Name : leuS (Ent638_1176)
Accession : YP_001175908.1
Strain : Enterobacter sp. 638
Genome accession: NC_009436
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1289926 - 1292610 bp
Length : 2685 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAGCAATACCGCCCGGAAGAGATAGAAACAAAAGTCCAGCAACACTGGGACGAGAAGCGTACTTTCGAAGTCAC
TGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCCTATCCTTCTGGTCGACTACATATGGGCCACGTGC
GTAACTACACCATCGGTGATGTGATCGCGCGCTACCAGCGTATGCTCGGTAAAAACGTCCTGCAACCGATTGGCTGGGAT
GCGTTTGGTCTGCCTGCGGAAGGCGCGGCGGTGAAAAACAACACGGCCCCTGCGCCGTGGACTTACGACAACATCGCTTA
CATGAAAAACCAGCTCAAAATGCTGGGCTTCGGTTATGACTGGAGCCGCGAGCTGGCGACCTGCACCCCAGAGTATTATC
GTTGGGAGCAAAAATTCTTCACCGAGCTGTACAAAAAAGGCCTGGTGTACAAGAAAACCTCTGCAGTGAACTGGTGTCCG
AACGACCAGACCGTTCTCGCGAACGAACAGGTTATTGACGGCTGCTGCTGGCGCTGCGATACCAAAGTTGAGCGCAAAGA
GATCCCACAGTGGTTCATCAAAATCACCGCTTACGCTGACGAGTTGCTGCGCGATCTGGACAATCTGGATCACTGGCCAG
ACACCGTTAAAACCATGCAGCGCAACTGGATTGGCCGTTCTGAAGGCGTAGAAATCACCTTCAACGTCGAAAACAGCGAT
CAGAAACTCACGGTGTATACCACGCGTCCTGACACCTTCATGGGTGCAACTTACCTGGCCGTTGCCGCGGGTCATCCGTT
GGCACAGCAGGCTGCTGCGAACAATCCAGCGCTGGCGGCTTTCATCGACGAATGCCGCAATACCAAAGTGGCAGAAGCCG
ACATGGCGACGATGGAGAAAAAAGGCGTTGCGACCGGGTTTAACGCGATTCACCCACTCACAGGTGAAGCGGTTCCCGTT
TGGGCTGCTAACTTTGTGCTGATGGAATACGGCACGGGTGCAGTCATGGCCGTTCCGGGCCACGATCAGCGCGATTACGA
ATTCGCGACCAAATACGGTCTTCCTATTAAGCGAGTAATCAAATCTCCAGAACAAAAAGCCTATGAGCATGCGCTTGAAT
ATGGACTTGGTTCTGCAAAGAATCCTAATGATTTTGAGCCATTAACTCATAATCAACGCTCTGAGTTCCTTGGATTGCTT
ACTGCAGAATTGAATAAGCCATACCTGGAAAAAGACGGTGAGACTTATAATTCCGGAAAATTTGATGGCCTGAGCTTTGA
AGCCGCATTTAATTCCATTGCTGCAGCACTGATTACCAAGGGCGTCGGTGAGCGTAAAGTGAACTATCGTCTGCGCGACT
GGGGTGTTTCCCGTCAGCGTTACTGGGGTGCGCCGATTCCAATGGTCACCCTGGAAGATGGCACCGTGCTGCCAACGCCA
GAAGACCAACTGCCGGTGATTTTGCCGGAAGACGTAGTCATGGACGGTATCAGCAGCCCGATTAAAGCCGATCCTGAGTG
GGCGAAAACCACCGTTAACGGTCAGCCAGCGCTGCGTGAGACGGATACGTTCGACACCTTTATGGAATCATCCTGGTATT
ACGCGCGCTACACTTGCCCGCAGTATCAGGAAGGTATGCTGGATTCCAAAGCAGCGAACTACTGGCTGCCGGTGGATATT
TACATCGGCGGTATTGAACACGCCATCATGCACCTGCTCTACTTCCGCTTCTTCCACAAGTTGATGCGTGATGCGGGTCT
GGTTAACTCTGACGAGCCAGCAAAACAGCTGCTGTGTCAGGGCATGGTTCTCGCGGATGCGTTCTACTATGTCGGCGTGA
ACGGTGAGCGTAACTGGGTCTCCCCGGTTGATGCGATCGTTGAGCGCGACGAGAAAGGCCGTATCGTGAAAGCGAAAGAC
GCGGCGGGCAATGAGCTGGTTTATACCGGCATGAGCAAGATGTCCAAGTCCAAAAACAACGGCATCGACCCGCAGGTCAT
GGTTGAACGTTACGGTGCCGATACCGTGCGTCTGTTCATGATGTTTGCATCCCCGGCGGATATGACGCTGGAATGGCAGG
AATCTGGCGTAGAAGGCGCGAACCGCTTCCTGAAACGCGTCTGGAAACTGGTCTACGAGCATACGTCTCAAGGTGAAGCG
CCAGCCCTGAACGTCGGTGCGCTGAGCGAAGATCAGCAGGCACTGCGTCGCGATGTTCACAAAACCATCGCAAAAGTAAC
CGATGATATTGGTCGTCGTCAGACCTTCAATACCGCAATTGCGGCTATTATGGAACTGATGAACAAGCTGGCGAGAGCAC
CGCAGGAAGGCGAGCAGGATCGTGCCTTGATGCGTGAAGCGCTGTTGGCCGTCGTTCGTATGCTGAACCCGTTCACACCA
CATGCGTGCTTTACCTTGTGGCAAGAACTGAAAGGCGAAGGCGATATCGATAACGCACCGTGGCCTGTTGCTGATGAGTC
AGCGATGGTTGAAAACACTACGCTGGTGGTGGTTCAGGTTAACGGTAAAGTACGTGGTAAAATTACCGTTGCAGTCGATG
CAACTGAAGAACAGGTTCGTGAACGCGCAGGCCAGGAACATCTGGTTGCGAAATACCTTGAGGGCGTTACCGTGCGTAAA
GTGATCTACGTACCCGGTAAACTGCTGAATCTGGTCGTTGGCTAA

Protein sequence :
MQEQYRPEEIETKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWD
AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLRDLDNLDHWPDTVKTMQRNWIGRSEGVEITFNVENSD
QKLTVYTTRPDTFMGATYLAVAAGHPLAQQAAANNPALAAFIDECRNTKVAEADMATMEKKGVATGFNAIHPLTGEAVPV
WAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLPIKRVIKSPEQKAYEHALEYGLGSAKNPNDFEPLTHNQRSEFLGLL
TAELNKPYLEKDGETYNSGKFDGLSFEAAFNSIAAALITKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTP
EDQLPVILPEDVVMDGISSPIKADPEWAKTTVNGQPALRETDTFDTFMESSWYYARYTCPQYQEGMLDSKAANYWLPVDI
YIGGIEHAIMHLLYFRFFHKLMRDAGLVNSDEPAKQLLCQGMVLADAFYYVGVNGERNWVSPVDAIVERDEKGRIVKAKD
AAGNELVYTGMSKMSKSKNNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTSQGEA
PALNVGALSEDQQALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLARAPQEGEQDRALMREALLAVVRMLNPFTP
HACFTLWQELKGEGDIDNAPWPVADESAMVENTTLVVVQVNGKVRGKITVAVDATEEQVRERAGQEHLVAKYLEGVTVRK
VIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-142 41