Gene Information

Name : thyA (PST_0414)
Accession : YP_001170962.1
Strain : Pseudomonas stutzeri A1501
Genome accession: NC_009434
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 467001 - 467819 bp
Length : 819 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
TTGGCGCCTGCTTCGAGTCAATCGATGAAACAGTATCTCGACCTGATGCGCCACGTGCGCGAACACGGCACCTTCAAGAG
CGACCGCACCGGCACCGGCACCTATAGCGTGTTCGGCTACCAGATGCGCTTCGACCTGGCCGAAGGCTTCCCGCTGGTGA
CCACCAAGAAGTGTCACCTCAAATCCATCATCCACGAGCTGCTGTGGTTCCTTCAGGGCGATACCAACATCAAGTACCTG
AAGGAAAACGGCGTGCGCATCTGGGACGAGTGGGCCGACGAGAACGGCGAGCTGGGCCCGGTCTACGGCTACCAGTGGCG
CTCCTGGCCGGCGCCGAACGGCGAGTCCATCGACCAGATTGCCAACCTGCTGGCGATGATCAAGAAGAATCCGGATTCGC
GCCGGCTGATCGTCTCGGCCTGGAATCCGGCGCTGGTCGAGCAGATGGCGCTGCCGCCGTGCCACGCCCTGTTCCAGTTC
TACGTCGCCGATGGCAAGCTCAGCTGCCAGCTGTACCAGCGCTCGGCCGACATCTTCCTCGGCGTGCCCTTCAACATCGC
CAGCTATGCCCTGCTGACGCTGATGGTGGCGCAGGTCTGCGACCTCGAGCCGGGCGAGTTCATCTGGAGTGGCGGCGATT
GCCACCTTTACGCCAACCACCTGGAGCAGGCCGATCTGCAGCTGACCCGCGAGCCGCTGCCGCTGCCGACCATGAAGCTC
AATCCCGAGGTGAAGGACCTGTTCGCCTTCCGCTTCGAGGACTTCGAGCTGGTCGGCTACGAGGCGCACCCGCACATCAA
GGCGCCCGTCGCCGTCTGA

Protein sequence :
MAPASSQSMKQYLDLMRHVREHGTFKSDRTGTGTYSVFGYQMRFDLAEGFPLVTTKKCHLKSIIHELLWFLQGDTNIKYL
KENGVRIWDEWADENGELGPVYGYQWRSWPAPNGESIDQIANLLAMIKKNPDSRRLIVSAWNPALVEQMALPPCHALFQF
YVADGKLSCQLYQRSADIFLGVPFNIASYALLTLMVAQVCDLEPGEFIWSGGDCHLYANHLEQADLQLTREPLPLPTMKL
NPEVKDLFAFRFEDFELVGYEAHPHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-85 65