Gene Information

Name : topB (PST_2913)
Accession : YP_001173401.1
Strain : Pseudomonas stutzeri A1501
Genome accession: NC_009434
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 3134600 - 3136447 bp
Length : 1848 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
GTGACGGTGACCTGGTGCATCGGCCATCTGCTGGAGACCGCCCCGCCGGACGCCTATGACCCGCGCTACAAGCGCTGGGT
GCTGGCCGACCTGCCGATCGTGCCGGAGCGCTGGAAGATGCTGGTCAAGCCGAAGACCGCCAGCCAGTTCAAGGCGGTCA
AGCGTCTGCTCGGTGAATGCAGGGAACTGGTGATCGCCACCGACGCCGACCGCGAAGGCGAGATGATCGCCCGCGAGCTG
GTTGAGCACTGCCGCTACCGCGGGCCCATCCGCCGGCTGTGGCTGTCGGCGCTGGACGATGCCTCGATCCGCAAGGCGCT
GGCTGCGCTCAAGCCCGGCGCCGAGACCTTCAACCTCTACCACGCCGCCCTCGGCCGCTCGCGTGCTGACTGGCTGATCG
GCATGAACATGAGCCGGCTGTTCACCCTGCTCGGCCGCCAGTCCGGCTACCGCGGCGTGCTGCCGGTGGGCCGCGTGCAG
ACGCCGACGCTGCGTCTGGTGGTGGACCGCGACCGCAGCATCGCCGATTTCATCCCGGTGCCGTTCTGGGCCATCGACGT
GCAGCTGCTCGCCGATGGCGCCGCGTTCACCGCGCAGTGGCAGGCGCCGGACGACCTTTGCGATGACCAGGGCCGCTGCC
TCGATCAGGCTCGTGCGCAGCAGGCTGCGGACGCCATGCGCAACGCCGCCAGCGCTCGCCTGCTGAAGCTCAAGACCGAG
CGGCAGCGCGAGGCGGCACCCTTGCCGTTCGATCTCGGCACGCTGCAGGAAGTCTGCTCGAAGAAGCTCGGCCTCGGCGC
CCAGGAAACCCTCGACATCGCCCAGGCGCTGTACGAAACCCACAAACTGATCACCTATCCGCGCAGCGATTGCGGCTACC
TGCCACTGAGCCAGCTCGGCGAAGCGCGGGCCATCGTCGCGGCGCTGACTCAAGCCGACCCGACGCTCGCGGCGCTGCAG
CCGCATCTGGACCTGTCGCGCCGCTCGCGGGCGTGGAATGACGCCAAGGTCGGCGCCCACCACGGCATCGTCCCAACCGC
CGCCGCGCGTGGTCTGGAACGCCTGGCCGGGCGCCCGCGTGCGGTGTATGAGCTGATCCGCGCGCGCTACCTGGCACAGT
TCCTGCCCAACCACGAGTACGACCGCACCCAGGCTGACTTCGACTGCGCCGGCCAGGCGCTGCGCGCGGTGGGCAAGCGC
GTCGTCGAACCGGGCTGGAAACGCGCCATGCCCGAAGCACTGGCGCCGGCACGGGGCAATCGCGAGGCACATGCGCCGCA
AAGCCTGCCGGCGCTGCAGCAGGGCCAGGACTATGCCGTGGGCGAGATCACACTCAAGGACCAGCAGACACAACCGCCGA
AGCCCTTCACCGAAGGCGACCTGATCAAGGCAATGAAGAACGTCGCCAAGCTCGTGGACGACCCGCGGCTGAAGCAGAAA
CTCAAGGACACCACCGGCATCGGCACCGAGGCGACCCGCGCCGGGATAATTCAGGGCCTGCTCGACCGCGGCTATCTGGT
TCGCCAGGGCAAGGCGCTGGCGGCGACACCGGCGGCGTTCAGCCTGATCGACGCCGTGCCGCGGCCGATCGCCGACCCGG
GTACCACGGCGATCTGGGAGCAGGCGCTGGACATGGTGCAGAGCGGCGAAATGCCGTTGGAGGAATTCGTCGCCAAGCAA
TCGGCGTGGATGAGCAAGCTGGTCGAACGCTGCGCCGGACTGCGCATGACCATCAGCGGCCCGCCGGTGGCCGCCGGCCG
CAACGGCAAACCGTGGAAGAAGAAACGCAGCGCCACGCCACGCAGAGGGAGCGGCGCTCGGACGAGAAAACCGCGCGCGG
CCGATTGA

Protein sequence :
MTVTWCIGHLLETAPPDAYDPRYKRWVLADLPIVPERWKMLVKPKTASQFKAVKRLLGECRELVIATDADREGEMIAREL
VEHCRYRGPIRRLWLSALDDASIRKALAALKPGAETFNLYHAALGRSRADWLIGMNMSRLFTLLGRQSGYRGVLPVGRVQ
TPTLRLVVDRDRSIADFIPVPFWAIDVQLLADGAAFTAQWQAPDDLCDDQGRCLDQARAQQAADAMRNAASARLLKLKTE
RQREAAPLPFDLGTLQEVCSKKLGLGAQETLDIAQALYETHKLITYPRSDCGYLPLSQLGEARAIVAALTQADPTLAALQ
PHLDLSRRSRAWNDAKVGAHHGIVPTAAARGLERLAGRPRAVYELIRARYLAQFLPNHEYDRTQADFDCAGQALRAVGKR
VVEPGWKRAMPEALAPARGNREAHAPQSLPALQQGQDYAVGEITLKDQQTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQK
LKDTTGIGTEATRAGIIQGLLDRGYLVRQGKALAATPAAFSLIDAVPRPIADPGTTAIWEQALDMVQSGEMPLEEFVAKQ
SAWMSKLVERCAGLRMTISGPPVAAGRNGKPWKKKRSATPRRGSGARTRKPRAAD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 2e-170 63
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 9e-177 61
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-173 61
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 6e-136 49
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 4e-136 49
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 6e-136 49
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 9e-135 48
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 3e-134 47
topB AAW83109.1 TopB Not tested GGI Protein 9e-101 41