Gene Information

Name : YPDSF_2295 (YPDSF_2295)
Accession : YP_001163643.1
Strain : Yersinia pestis Pestoides F
Genome accession: NC_009381
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2610413 - 2611165 bp
Length : 753 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAGTTTCATTGCTATAATTCCCGCCCGCTATGCTTCAACCCGTTTACCCGGCAAACCACTGGCTGATATTGCGGGCAA
ACCGATGGTCGTCCATGTTATGGAGCGGGCCTTGGCGTCAGGTGCTGACCGGGTGATTGTGGCAACAGACCATCCAGATG
TGGTCAAGGCGGTTGAGGCCGCAGGTGGTGAAGTGTGCCTGACCCGTGCTGATCATCAGTCTGGCACTGAACGGTTAGCC
GAAGTTATTGAACACTATGGTTTTGCTGATGACGATATTATCGTCAATGTTCAGGGCGATGAACCCCTGGTGCCGCCGGT
GATTATCCGTCAGGTTGCTGATAATTTGGCTGCATGTAGTGCCGGCATGGCGACGTTGGCTGTTCCCATTGCAAGCAGTG
AAGAGGCGTTTAACCCTAATGCCGTTAAAGTGGTTATGGATGCTCAGGGTTATGCCCTCTACTTTTCCAGGGCCACCATT
CCGTGGGAAAGAGAGCGCTTTGCTCAATCAAAAGAGACTATCGGTGATTGTTTCTTACGTCACATCGGTATCTATGCCTA
TCGAGCAGGTTTTATCCGTCGCTATGTTAACTGGGCACCCAGTCAGCTTGAGCAAATTGAATTGTTAGAGCAACTGCGGG
TGTTATGGTACGGCGAGAAAATTCACGTTGCGGTGGCGAAAGCTGTGCCTGCGGTTGGGGTTGATACGCAGAGCGATTTA
GACCGAGTCCGGGCTATCATGCTCAATCAATAA

Protein sequence : 
MSFIAIIPARYASTRLPGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGTERLA
EVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEAFNPNAVKVVMDAQGYALYFSRATI
PWERERFAQSKETIGDCFLRHIGIYAYRAGFIRRYVNWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAVPAVGVDTQSDL
DRVRAIMLNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 5e-28 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-28 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-28 44