Gene Information

Name : YPDSF_2126 (YPDSF_2126)
Accession : YP_001163478.1
Strain : Yersinia pestis Pestoides F
Genome accession: NC_009381
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : 2.7.1.60
Position : 2399558 - 2400430 bp
Length : 873 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGGGAAAAGGGTTAGCACTGGATATCGGTGGAACAAAAATTGCCGTCGCGGTGGTCACTGAGAGTGGCATGTTGATTGG
CCGCCAGCAAATAGCAACACCACGAGGCGGTGCCGGACAACTGGCTGCCGCACTGGAAACACTGATAGCGCCTTACCGCC
ATCAGGTTGATTTTATTGCTGTTGCGTCAACGGGCATTATCAGCGGGGGCCGTCTGACGGCGCTCAATCCGGCCAATTTG
GGCGGTCTGGCTGACTTCCCATTGTACGACTGTATTCGCTCTATCAGTGATCTGCCTTGTGTCCTGCTGAACGACGGTCA
GGCTGCGGCATGGGCTGAATACCAGGCGCTGGGTGATAAAAATGACAATATGATGTTTGTGACCGTTTCCACTGGTGTGG
GCGGCGGCATCATTTTGAATAAAAAACTGTTGGTCGGGCAACGTGGGCTGGCAGGGCATATCGGCCATACGCTGTCTGAT
CCTCATGGTGTTTTGTGTGGTTGCGGTCGCCGGGGATGTGTCGAGAGCGTGGCATCAGGCACGGCTATTGGGGCAGAAAC
CTTGGGGTGGAAGCAACCGGTATCGGCTGCCACGGTGTTTGACATGGCGCAGCAAGGGGATGCGCAGGCGGGAAAAGTCA
TTAACCGTTCTGCCGCAGCCATTGCTCAGATGTTGGCCGACATGAAGATGGCGCTGGATCTGGAGGTGGTTATTCTGGGG
GGCAGTGTCGGGTTGGCGGTTGGCTACCTGGAGAGGGTGGTTGCCGCCCAGAAGACATTACCGGGTATTTACCGCGTCCC
CGTACAAGAGGCACATCACCGTCAGGATAGTGGATTACTCGGGGCGGCACTGTGGGCCAGAACGTCGTTGTGA

Protein sequence : 
MGKGLALDIGGTKIAVAVVTESGMLIGRQQIATPRGGAGQLAAALETLIAPYRHQVDFIAVASTGIISGGRLTALNPANL
GGLADFPLYDCIRSISDLPCVLLNDGQAAAWAEYQALGDKNDNMMFVTVSTGVGGGIILNKKLLVGQRGLAGHIGHTLSD
PHGVLCGCGRRGCVESVASGTAIGAETLGWKQPVSAATVFDMAQQGDAQAGKVINRSAAAIAQMLADMKMALDLEVVILG
GSVGLAVGYLERVVAAQKTLPGIYRVPVQEAHHRQDSGLLGAALWARTSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 4e-38 46
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 8e-32 45
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 8e-32 45
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 4e-31 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPDSF_2126 YP_001163478.1 N-acetylmannosamine kinase VFG1115 Protein 3e-32 45