Gene Information

Name : fliI (YPDSF_1297)
Accession : YP_001162661.1
Strain : Yersinia pestis Pestoides F
Genome accession: NC_009381
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1462491 - 1463993 bp
Length : 1503 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGCTGGCGGCTGTAAAGTCAGCGCGGAAGAAGGCGATTTGGATGCCAGTCTGGCGACCCGTTGGCATGAACTGTGCCGT
CTGGCCGCGCCGGGGGAACTGTGATGCCCCCCGCCTCAGCCGCTGGCTTACCTCTTTAGATAAATTCGAAGAGCGTATCA
GCCAAACGACAACAATCCGCCGTTATGGCCGCTTGACCCGCGCCACCGGTTTAGTGCTGGAAGCCACTGGTCTGCAATTG
CCGTTAGGGGCGACCTGTCTGATTGAGCGCCATAATGGCGGTGAAGTGCAGGAAGTCGAAAGCGAAGTGGTTGGTTTTAA
CGGTCAGCATCTGTTTCTTATGCCTTTGGAAGATGTGGAAGGTATCGTCCCCGGTGCCAGAGTGTATGCCCGAGTCACCA
CCAGCGGCACGTCTGCCAGTAAACAGTCAATTTCTAGTAAACAATCATTCGCCAGTAAACAATTACCCCTTGGCCCCGAG
TTATTGGGCCGGGTATTGGATGGCAGTGCCAAACCGCTTGATGGCTTACCGGCACCTGAAACCGGTTATCGTGCACCACT
GATTACACCACCGATAAACCCTTTGCAACGCACCGCCATTGTCCAAGTCTTGGATGTGGGCGTGCGTACCATTAACGCCT
TGTTGACGGTCGGGCGCGGCCAGCGGATGGGGCTGTTTGCTGGCTCTGGGGTTGGCAAAAGCGTACTGCTCGGCATGATG
GCCCGTTACACACAGGCTGACGTGATCGTGGTTGGGCTGATTGGTGAGCGTGGCCGTGAAGTCAAAGATTTTATCGAAAA
TATTCTCGGGGCTGAAGGCCGTGCCCGTTCGGTGGTTATCGCCGCGCCAGCCGATGTGTCACCGTTGCTGCGTATGCAAG
GTGCCGCCTATGCCACCCGTATTGCCGAAGATTTCCGCGATCGTGGTCAGCATGTGTTGCTAATTATGGACTCCCTAACC
CGCTATGCCATGGCGCAACGTGAAATCGCGCTGGCTATCGGCGAGCCTCCCGCGACCAAAGGTTATCCGCCCTCCGTCTT
CGCCAAATTACCGGCACTGGTTGAACGGGCGGGTAACGGTGTTTCAGGCGGCGGCTCCATTACCGCATTTTATACCGTCC
TCACCGAAGGTGATGATCAGCAAGATCCTATTGCTGACTCTGCGCGCGCCATCCTCGATGGCCATGTGGTGCTATCTCGC
CGTTTGGCTGAATCCGGTCACTATCCGGCTATCGATATCGAAGCCTCTATCAGCCGTGCCATGACCTCATTAATCGATGA
TGACCATTACAGCCGGGTGCGCCAGTTTAAACAACTGCTTGCCAGTTATCAGCGTAACCGCGATTTGATCAGTGTCGGGG
CTTATGCTGCGGGCAGTGATCCCTTATTGGACAAGGCGATTGCCCTGTACCCACAGATGGAGGCTTTCTTGCAGCAAGGC
ATGTTTGAGCGCAGCAGTTTTGATGATGCCTGCCAGCATTTGAAGGTTTTATTTCCAGGATAA

Protein sequence :
MLAAVKSARKKAIWMPVWRPVGMNCAVWPRRGNCDAPRLSRWLTSLDKFEERISQTTTIRRYGRLTRATGLVLEATGLQL
PLGATCLIERHNGGEVQEVESEVVGFNGQHLFLMPLEDVEGIVPGARVYARVTTSGTSASKQSISSKQSFASKQLPLGPE
LLGRVLDGSAKPLDGLPAPETGYRAPLITPPINPLQRTAIVQVLDVGVRTINALLTVGRGQRMGLFAGSGVGKSVLLGMM
ARYTQADVIVVGLIGERGREVKDFIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLT
RYAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGVSGGGSITAFYTVLTEGDDQQDPIADSARAILDGHVVLSR
RLAESGHYPAIDIEASISRAMTSLIDDDHYSRVRQFKQLLASYQRNRDLISVGAYAAGSDPLLDKAIALYPQMEAFLQQG
MFERSSFDDACQHLKVLFPG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-76 46
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-77 46
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-76 46
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-76 46
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-76 45
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-76 45
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-76 45
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-73 45
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-73 45
lscN AAO18044.1 LscN Virulence TTSS locus Protein 5e-69 44
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-62 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 6e-70 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 9e-67 41
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-65 41
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-69 41
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-65 41
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-65 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_001162661.1 flagellum-specific ATP synthase VFG2331 Protein 0.0 93
fliI YP_001162661.1 flagellum-specific ATP synthase VFG2499 Protein 8e-141 67
fliI YP_001162661.1 flagellum-specific ATP synthase VFG1254 Protein 3e-117 59
fliI YP_001162661.1 flagellum-specific ATP synthase VFG0192 Protein 3e-76 44
fliI YP_001162661.1 flagellum-specific ATP synthase VFG2144 Protein 2e-80 43
fliI YP_001162661.1 flagellum-specific ATP synthase VFG0390 Protein 2e-71 42