Gene Information

Name : guaA (Strop_3833)
Accession : YP_001160641.1
Strain : Salinispora tropica CNB-440
Genome accession: NC_009380
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 4390324 - 4391877 bp
Length : 1554 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCACCCCGCGCCCCGTCCTGGTGGTGGACTTCGGAGCCCAGTACGCCCAGCTCATCGCACGCCGGGTACGGGAGGC
CCGGGTCTACTCGGAGATCGTTCCGCACACGTTGTCGGCGGCCGAGATGCTGGCGAAGGACCCGGCAGCGATCATTCTCT
CGGGCGGCCCGTCCAGCGTCTACGCGCCCGACGCGCCAGGTGTCGACCCCGGGGTGTTCGAGGTCGGGGTGCCGGTCTTC
GGCATCTGTTACGGCTTCCAGGCGATGGCTCAGGCGCTCGGGGGCACGGTCGCGAAGACCGGCAACGGCGAGTACGGCGG
CACTGTGCTGCGCCCGCGGTCGGAATGCGGGGTGCTGCTGCGTGATCTCCCTGGTGATCTTCCGGTCTGGATGAGCCACG
GCGACTGTGTGACGGAGGCGCCGGCTGGCTTCGCGGTGACCGCCGAGTCAGCGGGCGCCCCGGTGGCGGCCTTCGAGGAT
CGGGCCGGGCGACGGGCCGGGGTGCAGTTCCACCCGGAGGTCGGGCACACGGCGCATGGCCAGGAGATGTTGACCCGTTT
CCTCTACGACATCGCCGGCATCGAGCCCACCTGGACGCCGGAGAACATCATCGACGAGCAGGTGGCCCGGATCCGCGAGC
AGGTCGGCACCAAGGAGGTCATCTGCGGTCTCAGCGGCGGCGTTGACTCCGCGGTCGCCGCGGCGCTGGTGCACCGGGCT
GTTGGCGACCAGTTGACCTGTGTCTTCGTTGACCATGGTCTGCTTCGGGCGGGCGAGGCCGAGCAGGTGGAGAAGGACTA
CGTCGCCGCCACCGGAATCAAGCTGCGGGTGGTCGACGCGGCGGACCAGTTCCTGACCGCGTTGGCCGGGGTGACCGATC
CGGAACGCAAGCGCAAGATCATTGGCCGCGAGTTCATTCGGACGTTCGAGGCCGCTGCCCGGGACATCGCCGCCCACGGC
GACGTGGAGTTCCTGGTACAGGGCACCCTCTACCCGGACGTGGTGGAGTCCGGCGGTGGCGCGGGTACGGCCAGTATCAA
GAGCCATCACAACGTCGGCGGGCTTCCCGAAGATCTTGGATTCTCCCTGGTCGAGCCGCTGCGTACGCTCTTCAAGGACG
AGGTCCGGGCACTCGGCCTCCAGCTCGGCCTGCCAGAGGCGATGGTCTGGCGGCATCCGTTCCCCGGGCCGGGGCTCGCG
ATCCGGATCATCGGTGCGGTCGACCAGGAACGGCTCGACGTGCTCCGCCGGGCCGATTTCATCGCCCGACAGGAGCTCAG
CGCTGCTGGCCTGGACCGGGGCGTGTGGCAGTTCCCGGTGGTTCTCCTGGCCGACGTACGCAGTGTGGGCGTGCAGGGAG
ACGGACGCAGCTACGGGCACCCTGTGGTGCTGCGCCCGGTCTCCAGCGAGGACGCGATGACGGCCGACTGGTCGCGGCTG
CCGTATGACCTGATCGCCCGGATCTCCACCCGGATCACCAACGAGGTCGCCGAGGTGAACCGGGTGGCTCTGGATGTCAC
CAGCAAGCCGCCGGGCACCATCGAGTGGGAGTGA

Protein sequence :
MSTPRPVLVVDFGAQYAQLIARRVREARVYSEIVPHTLSAAEMLAKDPAAIILSGGPSSVYAPDAPGVDPGVFEVGVPVF
GICYGFQAMAQALGGTVAKTGNGEYGGTVLRPRSECGVLLRDLPGDLPVWMSHGDCVTEAPAGFAVTAESAGAPVAAFED
RAGRRAGVQFHPEVGHTAHGQEMLTRFLYDIAGIEPTWTPENIIDEQVARIREQVGTKEVICGLSGGVDSAVAAALVHRA
VGDQLTCVFVDHGLLRAGEAEQVEKDYVAATGIKLRVVDAADQFLTALAGVTDPERKRKIIGREFIRTFEAAARDIAAHG
DVEFLVQGTLYPDVVESGGGAGTASIKSHHNVGGLPEDLGFSLVEPLRTLFKDEVRALGLQLGLPEAMVWRHPFPGPGLA
IRIIGAVDQERLDVLRRADFIARQELSAAGLDRGVWQFPVVLLADVRSVGVQGDGRSYGHPVVLRPVSSEDAMTADWSRL
PYDLIARISTRITNEVAEVNRVALDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-164 71
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-129 50
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-128 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-129 50