Gene Information

Name : leuS (Strop_3225)
Accession : YP_001160037.1
Strain : Salinispora tropica CNB-440
Genome accession: NC_009380
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3694890 - 3697754 bp
Length : 2865 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACTGAGGCAGCCGCACCGGCCAGCGACATTCCCCCCTTCCGCTACACCGCGGACCTGGCCGACGAGATCGAGCGCCG
TTGGCAGGACACCTGGGAACGCGAGGGCACCTTCCACGCTCCCAACCCGACCGGCCCGCTGGCCGACCCCGAGCATCCGC
GGGCGGGAGCGGAGAAGCTGTACGTACTGGACATGTTCCCGTACCCGTCGGGCGCTGGCCTGCACGTCGGCCACCCGCTG
GGCTACATCGGCACCGACTGCTTCGCCCGCTATCAGCGGATGGCCGGGCGGAACGTGCTGCACGCGATGGGCTTCGACGC
CTTCGGGCTCCCCGCTGAGCAGTACGCGGTGCAGACCGGCACCCACCCGCGTACCACCACCGAGGCGAACATCGCCCGGT
ACAAGGCACAGCTGCGCCGGCTGGGGCTGGCCCACGACGAACGCCGCTCGGTGGCCACCATCGACGCCGACTTCTACCGC
TGGACCCAGTGGGTCTTCCTGCAGATCTACAACGCCTGGTATGACAGCTCGGCGAAGCGGGCCCGCCCGATCGCCGAACT
GGTCGCCGAGTTCTCCGGTGGTTCCCGGCGCACCCCGGACGGGCGACCGTGGGGCGAGCTGACCGACGCCGAGCGGCGGG
CCGTTGTTGACCAGCACCGGCTGGCGTACGTCTCGCAGGCACCGGTCAACTGGTGCCCGGGACTGGGCACGGTGCTGGCC
AACGAGGAGGTCACCGCCGACGGCCGCTCCGAGCGGGGGAACTTCCCGGTCTTCAAGCGGAACCTGAAGCAGTGGATGAT
GCGGATCACCGCGTACGGTGACCGGCTGCTGGACGACCTGGAGAAGCTGGACTGGCCCGAGCCGATCAAGCTGATGCAGC
GGAACTGGATCGGCCGCTCCACCGGCGCGCACATCGAGTTCCCCACCTCGGCCCCGGATTCGGATGCGGAGGGCGAGCCG
CGGATCAGCGTCTTCACCACCCGGCCGGACACGATCTTCGGCGCCACCTACCTGGTGCTGGCGCCCGAGCATGACCTGGT
CGACACCCTGGTACCGACGGCCTGGCCGGCGGGGGTTCCCCAGGCCTGGACCGGCGGGCAGGCCAGTCCACGGGAGGCGG
TGGCGGGCTACCGCAAGGTGGCCGCGGCGAAGACCGACCTCGAGCGGCAGGCCGAGACGAAGGAGAAGACCGGCGTCTTC
ATCGGGTCGTACGCCACCAACCCGGTCACCGGGGCCCAGATTCCGATCTTCATCGCCGACTACGTGCTGGCTGGCTACGG
GACCGGCGCGATCATGGCGGTGCCTGGTCAGGACGAGCGGGACTGGGCCTTCGCCGAGGTGTTCGACCTGCCCATCGTCC
GCACCGTCCAGCCGGCGGAGGGCTTTGCCGGTAAGGCGTACACCGGTGACGGCCTGGCCATCAACAGCGCCACGCCCGAA
CGCGGCCTGGACCTGAACGGCCTGGGCGTCGCCGAGGCCAAGGCCCGGACCATCGCCTGGCTGGAGGCGGGCGGCCACGG
CTCGGGCGCGGTGACCTACCGGCTGCGGGACTGGCTGTTCAGCCGGCAGCGGTACTGGGGTGAGCCGTTCCCGATCGTGT
ACGACGAGACCGGCGCCGCCATCGCCCTGCCGGAGGAACTGCTGCCGGTCGAGCTGCCCGAGGTGGATGACTTCGCGCCC
CGCACCTTCGATCCCTCGGACGCGGAGTCGAACCCGGAGACCCCGCTGTCGCGACGGCGGGACTGGGTCGAGGTGGAGCT
GGACCTGGGCGACGGTCCGAAGCGCTACACCCGGGAGACCAACGTGATGCCGCAGTGGGCCGGCTCCTGCTGGTACGAGC
TGCGGTACCTGGATCCGACCAACGGCGACCGCTTCGTCGACCCGGAGGCCGAGCGGTACTGGATGGGCCCACGCGGCGAG
GGCGACTGCGGGGGCACCGACCTGTACGTCGGCGGTGCCGAGCATGCCGTACTGCACCTGCTCTATGCGCGGTTCTGGCA
CAAGGTGCTGTACGACCTGGGGCACGTGTCGAGCTTCGAGCCGTTCCGCAAGCTGTTCAACCAGGGCTACATCCAGGCAT
ACGCGTACACCGACGCGCGCGGGGCATACGTGCCGGCGGAGGAGGTCGTCGAGCGCTCCGGCACCTACTACCTGGGTGAT
GTCCAGGTCAACCGCGAGTACGGCAAGATGGGCAAGTCCCTGCGGAACGTGGTGACACCGGACGAGATGTGCGCCGCGTA
CGGGGCGGACACGTTCCGGGTGTACGAGATGTCGATGGGCCCGCTGGAGGTCTCCCGTCCCTGGGAGACGCGGGCGGTGG
TGGGATCGTTCCGGTTCCTGCAGCGGGTCTGGCGGGCGATCGTGGACGAACGCAGCGGCGCGTCCCGCGTGGTGGACGTG
CCGGCCGACGAGGCGACCCGCCGACTGCTGCACCGGATCGTGGACGGGGTCCGGGGCGACATGGAAGCGATGCGGTTCAA
CACCACGATCGCGAAGCTGATCGAGCTGACCAACGCACTGACCCGGCTGCCGGAGACGCCGCGTGAGGTGGCCGAACCGC
TGGTGCTGATGCTGGCGCCGTTCGCTCCGCACGTCGCCGAGGAGCTGTGGCGCCGGATGGGCCACGAGACGTCGTTGACC
TACGCGGACTTCCCGGTCGCGGACCCGGCCCTGCTGGTGGCCGAGTCGGTGACCTACCCGGTGCAGGTCAACGGCAAGGT
GCGGGGTCGGATCGAGGTGCCGGCCGACGCTGGGCAGGAGACCGTCCGCGCGGCGGCGCTGGAGGCGGTCGCCGCCTCGC
TGGCCGGCAAGGAACCCCGCAAGGTCATCGTGGTCCCCGGCCGAATGGTCTCCGTGGTGGCCTGA

Protein sequence :
MTEAAAPASDIPPFRYTADLADEIERRWQDTWEREGTFHAPNPTGPLADPEHPRAGAEKLYVLDMFPYPSGAGLHVGHPL
GYIGTDCFARYQRMAGRNVLHAMGFDAFGLPAEQYAVQTGTHPRTTTEANIARYKAQLRRLGLAHDERRSVATIDADFYR
WTQWVFLQIYNAWYDSSAKRARPIAELVAEFSGGSRRTPDGRPWGELTDAERRAVVDQHRLAYVSQAPVNWCPGLGTVLA
NEEVTADGRSERGNFPVFKRNLKQWMMRITAYGDRLLDDLEKLDWPEPIKLMQRNWIGRSTGAHIEFPTSAPDSDAEGEP
RISVFTTRPDTIFGATYLVLAPEHDLVDTLVPTAWPAGVPQAWTGGQASPREAVAGYRKVAAAKTDLERQAETKEKTGVF
IGSYATNPVTGAQIPIFIADYVLAGYGTGAIMAVPGQDERDWAFAEVFDLPIVRTVQPAEGFAGKAYTGDGLAINSATPE
RGLDLNGLGVAEAKARTIAWLEAGGHGSGAVTYRLRDWLFSRQRYWGEPFPIVYDETGAAIALPEELLPVELPEVDDFAP
RTFDPSDAESNPETPLSRRRDWVEVELDLGDGPKRYTRETNVMPQWAGSCWYELRYLDPTNGDRFVDPEAERYWMGPRGE
GDCGGTDLYVGGAEHAVLHLLYARFWHKVLYDLGHVSSFEPFRKLFNQGYIQAYAYTDARGAYVPAEEVVERSGTYYLGD
VQVNREYGKMGKSLRNVVTPDEMCAAYGADTFRVYEMSMGPLEVSRPWETRAVVGSFRFLQRVWRAIVDERSGASRVVDV
PADEATRRLLHRIVDGVRGDMEAMRFNTTIAKLIELTNALTRLPETPREVAEPLVLMLAPFAPHVAEELWRRMGHETSLT
YADFPVADPALLVAESVTYPVQVNGKVRGRIEVPADAGQETVRAAALEAVAASLAGKEPRKVIVVPGRMVSVVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-146 47