Gene Information

Name : Strop_2803 (Strop_2803)
Accession : YP_001159622.1
Strain : Salinispora tropica CNB-440
Genome accession: NC_009380
Putative virulence/resistance : Virulence
Product : AMP-dependent synthetase and ligase
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 3203139 - 3204737 bp
Length : 1599 bp
Strand : +
Note : PFAM: AMP-dependent synthetase and ligase

DNA sequence :
ATGCTGACCGGATGCGTCCCCTGGCCCGATGAGTTCGCGCAGCGCTACCGGCGCGACGGCATCTGGCGCGGCGAGGTACT
GGGAGACCTGCTCCGCCCCGAGGCGGCCGACGACCCTGACCGGATCGCCGTGGTCACCCGCCACGGTCGGCACAGCTACG
CCGAACTCGACCGGCGCGCCGACCGGCTGGCGGCCGGACTGGTCGGACTGGGTATCCGGGCCGACGACCGGGTCGTCGTC
CAGCTGCCGAACACGCCGGACTTCGTCGTGACGTGTGTGGCGCTTTTTCGGATCGGTGCCCTGCCGGTGCTCGCGCTGCC
CGCCCACCGCCGCTCCGAGCTGGTCTACCTCGCCGAGTACTCCGGTGCCGTCGCCCTGGTGGTGCCGGACCTGCTGGCGG
GCACCGACCACCGCACGTTGGCCCGCGCCGTGCGGGCGGCGGTGCCGAGCGTCGCACACCTCCTCGTCGCCGGCGAGGCG
CAGGAGCTGACCCCGCTGGCCGGCATTGACGCCAGCCCGCTGGACCTGCCCACCCCCGACCCGTCCGCGGTGGCGTTCTT
CCTGCTCTCCGGCGGCACCACCGGCCTGCCCAAGTTGATCCCGCGGACCCACGACGACTACACCTTCCAGCTACGGGCCA
CTGCCGAAGCGATGAGGTTCGACGAGAACGGCGCCTACCTGGCTGCCCTGCCGGTGGCGCACAACGCGGCGCTGGGCTGC
CCCGGGGTGCTGGGAGCGCTGCGCGCGGGTGGGCGCGCCGTACTCGCCGCCAGCCCGGCCCCGGACGAGGTTTTCCCACT
CGTCTCAACCGAGTCGGTCACCCTGACCACGCTGATGCCGGCGCTGCTGCCGGTCTGGATGGAAACCGCCGGGATCTTCG
GCGTCGACCTGTCCCAGCTGGTCATCGAGGTCGGCGGCGCCACGCTCAGTCCCGACGTGGCCCGTCAGGTCCGCCCCACC
ACCGGCGCGACCCTGACCCACTGGTTCGGCATGGCCGAGGGTGTCCTCTCCTTCACCCGCCCGGACGACGACGACGAGGT
CACCGCGACCACTCAGGGCACCCCGCTCAGCCCCGCCGACGAGCTGCGGGTCGTCGACGACACCGACCAGGACGTCGCTG
CCGGCGAAGTCGGCGAGCTCCTGGCCCGCGGCCCGTGCACGCTGCGCGGCTACTACGCGGTGCCCGAACACAACCGAACG
GTGTTCACCCCCGACGGCTTCCTCCGCACCGGCGACCTGGTCCGCCGCGACGCCGAGGGACGGCTGGTGGTGGTCGGCCG
AATCAAGGACGTGATCAACCGCGGCGGGGAGAAAGTCTCCGTCGACGAGGTCGAGGCGCACCTGCTGGCCCATCCGGCGG
TCCGGTCGGCGGCCGTCGTACCGGTGCCGGACTCCCGCCTGGGTGAGAAGACGTGCGCCGTGGTCGTCGCCCAGGACGAC
CCGCCCAGCCTGGCCGAGGTACGCGCCTTCCTGAGCGACAGAGGACTGGCCGAGTTCAAACTGCCGGACCGGTTGCACCT
GACGGCGGCCTTGCCGTACACGCCGGTAGGCAAGATCGACCGTCGGGCGTTAGCCCGCGACCACGCCGGTACGGCATGA

Protein sequence :
MLTGCVPWPDEFAQRYRRDGIWRGEVLGDLLRPEAADDPDRIAVVTRHGRHSYAELDRRADRLAAGLVGLGIRADDRVVV
QLPNTPDFVVTCVALFRIGALPVLALPAHRRSELVYLAEYSGAVALVVPDLLAGTDHRTLARAVRAAVPSVAHLLVAGEA
QELTPLAGIDASPLDLPTPDPSAVAFFLLSGGTTGLPKLIPRTHDDYTFQLRATAEAMRFDENGAYLAALPVAHNAALGC
PGVLGALRAGGRAVLAASPAPDEVFPLVSTESVTLTTLMPALLPVWMETAGIFGVDLSQLVIEVGGATLSPDVARQVRPT
TGATLTHWFGMAEGVLSFTRPDDDDEVTATTQGTPLSPADELRVVDDTDQDVAAGEVGELLARGPCTLRGYYAVPEHNRT
VFTPDGFLRTGDLVRRDAEGRLVVVGRIKDVINRGGEKVSVDEVEAHLLAHPAVRSAAVVPVPDSRLGEKTCAVVVAQDD
PPSLAEVRAFLSDRGLAEFKLPDRLHLTAALPYTPVGKIDRRALARDHAGTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE CAA21394.1 - Virulence HPI Protein 3e-77 47
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-77 47
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 5e-77 47
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 2e-77 47
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 7e-77 47
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-77 47
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 3e-77 47
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-77 47
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 3e-77 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Strop_2803 YP_001159622.1 AMP-dependent synthetase and ligase VFG1817 Protein 8e-86 48
Strop_2803 YP_001159622.1 AMP-dependent synthetase and ligase VFG0168 Protein 6e-86 46
Strop_2803 YP_001159622.1 AMP-dependent synthetase and ligase VFG0932 Protein 5e-75 42