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Name : guaA (Pnuc_1422) Accession : YP_001156200.1 Strain : Polynucleobacter necessarius QLW-P1DMWA-1 Genome accession: NC_009379 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 1492495 - 1494102 bp Length : 1608 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : GTGCACGACAAAATACTGATTCTCGACTTTGGTTCGCAAGTTACTCAATTAATTGCAAGACGTGTGCGAGATGCACGCGT GTATTCAGAGATCCATCCCTACGATTGTGATCCAGAGTTCATCCGCAAATTTATTCAGGAACAGGGCGGTAAAGGCATCA TCCTCTCTGGCGGACCTAATTCAGTTACTGAAGATGGCAGTCCTCGTGCCCCTCAAATCGTATTTGAGCTAGGCGTACCC GTTCTCGGCATTTGTTACGGTATGCAAACCATGGCAACCCAGCTAGGTGGCGCTGTCGCTTCGGCGGAGTCTCTTGGTAA AGCTCGCGAATTTGGATATTCGGAAGTTCGTGCTCATGGGCACACTAATTTACTTAAAGGCATCCAGGATTTTTCTACCA GCGAAGGCCATGGCATTCTGAAGGTATGGATGAGTCATGGAGATTCAGTAACCGCATTGCCTCCAGCATTTAAGTTGATG GCTTCAACCGAGTCTTGCCCAATAGCGGGTATGGCCGATGAAGATCGCCGCTTTTATGCATTTCAGTTTCATCCAGAAGT TACGCACACTATTCAAGGCACGGCGATCATTGAACGCTTTGTCCATGAAATTTGCCATTGCAAGCCTGACTGGGTCATGG GTGACTACATTGCTGAAGCGGTAGAGCATATTCGTAAACAAGTCGGAGATGAAGAAGTCATACTCGGTTTATCTGGTGGC GTTGACTCGAGTGTTGCTGCAGCGTTGATCCATCGGGCAATTGGCGATCAACTCACTTGCGTGTTTGTGGATCACGGTTT GCTTCGTCTCAATGAAGGCGACATGGTCATGGAGATGTTTGCACGTAACCTGGGTGTGAAAGTGATACGCGTTGACGCTG CATCTACCTTTATGGGTAAGTTAACTGGTGTTGCTGACCCAGAAGCAAAGCGCAAAATTATTGGTAAAGAATTTGTAGAG ATCTTCCAAAGCGAATCTGGCAAGATTGAGAATGCCAAGTGGCTTGCGCAAGGCACTATTTATCCGGACGTGATTGAGTC TGCTGGTAAGGGTAAGAAGGGCGCACATACTATTAAGAGTCATCACAACGTTGGCGGCTTACCTGAAGATATGCATCTAA AATTGCTTGAGCCATTGCGTGAGCTATTTAAAGATGAGGTGCGTGAATTAGGTGTTGCTTTAGGTCTTCCACGTGAGATG GTTTATCGCCATCCCTTCCCAGGCCCTGGTTTGGGAGTGCGCATCTTGGGTGAAGTGAAAGCAGAATTTGCTAGCCTGCT CCAGCGCGCAGATGCTATCTTTATTGAAGAGCTACGCAATACGATTGATGAAGTGAGCCAAAAATCTTGGTATGACTTAA CAAGTCAAGCATTCGCGGTCTTCTTGCCGGTTAAATCTGTTGGCGTGATGGGTGATGGCAGAACATATGAATATGTCGTT GCACTCAGAGCTGTACAAACGCAAGACTTCATGACAGCGCATTGGGCCCATTTGCCGCATGAGTTGTTGGGCAAAGTTTC TAATCGCATCATCAACGAAGTGCGTGGTATCAATCGAGTTGTTTACGATATCAGCGGAAAACCGCCAGCAACAATCGAGT GGGAATAG Protein sequence : MHDKILILDFGSQVTQLIARRVRDARVYSEIHPYDCDPEFIRKFIQEQGGKGIILSGGPNSVTEDGSPRAPQIVFELGVP VLGICYGMQTMATQLGGAVASAESLGKAREFGYSEVRAHGHTNLLKGIQDFSTSEGHGILKVWMSHGDSVTALPPAFKLM ASTESCPIAGMADEDRRFYAFQFHPEVTHTIQGTAIIERFVHEICHCKPDWVMGDYIAEAVEHIRKQVGDEEVILGLSGG VDSSVAAALIHRAIGDQLTCVFVDHGLLRLNEGDMVMEMFARNLGVKVIRVDAASTFMGKLTGVADPEAKRKIIGKEFVE IFQSESGKIENAKWLAQGTIYPDVIESAGKGKKGAHTIKSHHNVGGLPEDMHLKLLEPLRELFKDEVRELGVALGLPREM VYRHPFPGPGLGVRILGEVKAEFASLLQRADAIFIEELRNTIDEVSQKSWYDLTSQAFAVFLPVKSVGVMGDGRTYEYVV ALRAVQTQDFMTAHWAHLPHELLGKVSNRIINEVRGINRVVYDISGKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 2e-124 | 51 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 9e-125 | 51 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 9e-125 | 51 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 2e-110 | 48 |
