Gene Information

Name : YPDSF_3977 (YPDSF_3977)
Accession : YP_001154606.1
Strain :
Genome accession: NC_009377
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 31329 - 32648 bp
Length : 1320 bp
Strand : -
Note : TIGRFAM: ATPase FliI/YscN: (4.1e-213); SMART: ATPase (9.2e-10)

DNA sequence :
ATGCTCTCACTAGATCAGATACCTCATCATATTCGTCATGGCATTGTAGGTAGCCGCCTAATCCAAATTAGAGGACGTGT
CACTCAAGTGACAGGAACGTTATTAAAAGCGGTAGTGCCAGGTGTGCGCATCGGTGAGTTATGTTACTTACGTAACCCTG
ACAACAGCCTGTCTTTACAGGCTGAAGTCATAGGTTTTGCCCAACATCAAGCATTACTTATTCCACTTGGTGAAATGTAC
GGGATATCTTCTAATACTGAAGTTAGCCCGACAGGGACAATGCATCAGGTTGGGGTGGGTGAACATCTGCTGGGACAGGT
GTTGGATGGTTTAGGGCAGCCTTTCGATGGGGGGCATCTCCCTGAACCGGCGGCTTGGTACCCAGTTTATCAGGATGCCC
CAGCGCCGATGAGCCGAAAACTTATTACCACACCACTTTCTTTGGGGATCCGGGTTATTGACGGTTTGCTTACCTGTGGC
GAGGGGCAAAGAATGGGCATCTTCGCGGCCGCCGGGGGGGGGAAAAGTACACTGCTTGCTTCGCTTATTCGTAGTGCTGA
AGTAGACGTAACCGTGCTGGCGCTTATTGGTGAGCGTGGACGCGAAGTGCGTGAGTTTATTGAGTCTGATTTAGGCGAAG
AGGGGTTACGCAAAGCGGTTCTCGTGGTGGCCACCTCGGATCGGCCCTCACTGGAAAGAGCCAAAGCTGGATTCGTGGCG
ACATCTATTGCTGAATATTTTCGCGATCAAGGGAAACGCGTATTGTTACTTATGGACTCTGTAACACGGTTTGCTCGTGC
TCAGCGTGAAATAGGCTTAGCTGCGGGAGAACCACCGACTCGCCGCGGTTATCCTCCGTCAGTATTTGCCGCTTTACCCC
GTTTGATGGAAAGGGCTGGTCAGTCCAGCAAAGGGTCAATTACGGCTCTCTATACCGTACTGGTCGAAGGGGACGATATG
ACCGAACCCGTGGCCGACGAAACACGTTCGATACTTGATGGTCATATTATTCTGTCACGGAAATTAGCGGCAGCTAATCA
TTATCCTGCCATTGACGTATTACGTTCAGCGAGCAGGGTGATGAATCAAATTGTCAGCAAGGAGCACAAAACCTGGGCGG
GGGACTTACGCCGTTTATTGGCCAAATATGAAGAAGTGGAATTGCTGTTGCAAATCGGGGAGTACCAGAAAGGGCAAGAC
AAAGAGGCCGATCAAGCGATTGAACGCATGGGGGCGATTCGAGGATGGCTCTGCCAGGGGACGCACGAGTTAAGCCATTT
CAATGAGACGCTGAACTTATTGGAGACGCTGACCCAATGA

Protein sequence :
MLSLDQIPHHIRHGIVGSRLIQIRGRVTQVTGTLLKAVVPGVRIGELCYLRNPDNSLSLQAEVIGFAQHQALLIPLGEMY
GISSNTEVSPTGTMHQVGVGEHLLGQVLDGLGQPFDGGHLPEPAAWYPVYQDAPAPMSRKLITTPLSLGIRVIDGLLTCG
EGQRMGIFAAAGGGKSTLLASLIRSAEVDVTVLALIGERGREVREFIESDLGEEGLRKAVLVVATSDRPSLERAKAGFVA
TSIAEYFRDQGKRVLLLMDSVTRFARAQREIGLAAGEPPTRRGYPPSVFAALPRLMERAGQSSKGSITALYTVLVEGDDM
TEPVADETRSILDGHIILSRKLAAANHYPAIDVLRSASRVMNQIVSKEHKTWAGDLRRLLAKYEEVELLLQIGEYQKGQD
KEADQAIERMGAIRGWLCQGTHELSHFNETLNLLETLTQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-175 88
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 4e-115 61
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 4e-115 61
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-114 61
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-114 61
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-114 61
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-114 61
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-115 61
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-114 61
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 1e-114 61
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 9e-101 57
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-100 57
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-100 57
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-100 57
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 9e-101 57
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-100 57
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-92 54
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 5e-86 53
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-88 53
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 1e-91 53
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-91 53
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 2e-91 53
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-93 52
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-93 52
unnamed AAL06369.1 EscN Virulence LEE Protein 3e-96 52
ECs4568 NP_312595.1 EscN Virulence LEE Protein 3e-96 52
escN AAK26715.1 EscN Virulence LEE Protein 9e-97 52
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-96 52
escN AAL57542.1 EscN Virulence LEE Protein 9e-97 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-97 52
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-97 52
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-97 52
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-97 52
escN AAC38383.1 EscN Virulence LEE Protein 3e-96 52
escN AAC31513.1 L0034 Virulence LEE Protein 3e-96 52
escN NP_290268.1 hypothetical protein Virulence LEE Protein 3e-96 52
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-96 52
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-87 52
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-87 52
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 5e-97 52
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 6e-88 51
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 6e-84 51
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 6e-84 51
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 2e-78 48
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-84 47
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-84 47
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-84 47
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-84 47
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-82 47
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-82 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG0390 Protein 0.0 99
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG0192 Protein 1e-168 84
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG0048 Protein 2e-137 68
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG0515 Protein 9e-101 57
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG2144 Protein 9e-110 56
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG0812 Protein 1e-96 52
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG0730 Protein 2e-96 52
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG0555 Protein 6e-85 47
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG1254 Protein 3e-83 47
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG2459 Protein 1e-84 46
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG2331 Protein 3e-74 45
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG1008 Protein 1e-78 45
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG1778 Protein 5e-83 45
YPDSF_3977 YP_001154606.1 type III secretion system ATPase VFG2499 Protein 1e-75 45