Gene Information

Name : thyA (ASA_0676)
Accession : YP_001140587.1
Strain : Aeromonas salmonicida A449
Genome accession: NC_009348
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 690536 - 691330 bp
Length : 795 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAGGGTTTATCTCGACCTGATGCAGAAGATCCTGGATGAGGGCACCGTCAAGTCCGATAGGACTGGTACTGGTACCGT
CTCCCTGTTCGGCCATCAGATGCGCTTCAATCTGGCGCAGGGTTTCCCGCTGGTCACCACCAAGAAATGTCACCTGCGTT
CCATCATTCACGAGCTGCTCTGGTTCCTCAATGGCGACACCAATACCGCCTATCTGAAAGAGCAGGGTGTCAGCATCTGG
GATGAGTGGGCAGACGAGAATGGCGATCTGGGTCCGGTTTATGGCGCTCAGTGGCGCTCCTGGCCGGCGGCCGATGGTGC
TGTCATCGATCAGATCCAGCGTGCTGTGGATGACATCAAGCACAATCCGGATTCGCGCCGCATCATAGTCTCAGCCTGGA
ACGTAGGTGAACTGGACAAAATGGCGCTGGCTCCCTGCCACGCCTTCTTCCAGTTCTACGTGGCAGATGGAAAGCTCTCG
TGTCAGCTCTACCAGCGCAGCTGTGATGTCTTCCTCGGCCTGCCGTTCAATATCGCCAGCTATGCTCTGCTAACTCACAT
GATGGCTCAGCAGTGTGATCTGGAAGTGGGCGACTTCGTCTGGACCGGGGGTGATGTGCACCTCTACTCCAACCATATGG
AGCAGACTGCGCTGCAGCTCTCTCGTGAGCCGAGGCCCTTGCCTCAGCTGGCGATCAAGCGAAAGCCCGATTCCATCTTC
GACTATCGGTTCGAGGATTTCGAAATCCTGGGGTATGACCCTCATCCCGGTATCAAGGCGCCCGTCGCCATCTGA

Protein sequence :
MRVYLDLMQKILDEGTVKSDRTGTGTVSLFGHQMRFNLAQGFPLVTTKKCHLRSIIHELLWFLNGDTNTAYLKEQGVSIW
DEWADENGDLGPVYGAQWRSWPAADGAVIDQIQRAVDDIKHNPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLTHMMAQQCDLEVGDFVWTGGDVHLYSNHMEQTALQLSREPRPLPQLAIKRKPDSIF
DYRFEDFEILGYDPHPGIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-88 68