Gene Information

Name : hemC (ASA_3875)
Accession : YP_001143577.1
Strain : Aeromonas salmonicida A449
Genome accession: NC_009348
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 4161818 - 4162765 bp
Length : 948 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAAACAACTGATTGATATGGCAGCCCGAACCCTGAAAATTGCCACTCGCAAGAGCCCATTGGCCCTGTGGCAGGCCAA
CTTCGTCAAAGACCGGCTGGAAGCCCTGTACCCCGAGTTGCAGGTCGAGCTGGTGCCCATGAGCACTCAGGGTGACAAGA
TCCTGGATACCCCTCTCGCCAAAGTGGGTGGCAAGGGGTTGTTCGTCAAGGAGCTGGAAACCGCCATGCTGGAGGGCCGC
GCCGACATCGCCGTCCACTCCATGAAGGATGTGCCGGTGGAGTTCCCGGAAGGGCTGGGCCTGCACACCATCTGTGAGCG
CGAAGATCCGCGCGATGCCTTCGTTTCCAACCGTTTCAGCCAGATAGAAGCACTGCCGCAGGGCGCCGTGGTCGGCACCT
CCAGCCTGCGCCGTCAGTGTCAACTGCGGGCCGCCCGCCCGGATCTGGTGATCCGCGACCTGCGTGGCAACGTCAATACC
CGTCTCGCCAAGCTGGATGCCGGTGAATATGACGCCATCATTCTTGCCGCCGCCGGCCTGAAGCGTCTGGAGATGGCACA
TCGCATCACCGCCTTCATCGAGCCGGAGCAGAGCCTGCCTGCCAACGGTCAGGGTGCGGTCGGCATCGAATGCCGCCTCG
ACGATCACGAGCTGCACACCCTGTTGGCACCGCTGGAGCACGCCGAGACCCGGATACGGGTGCTGACCGAGCGAGCCATG
AACCGCGCCCTGCAAGGGGGCTGTCAGGTCCCTATTGGCGCCTACGCTCTGGTACAGGGGGATGAGGTCTGGTTGCGCGG
TCTGGTGGGCAGCCCGGATGGCAGTCAGGTGATCCACGACGAGATCCGCGGTCCGCTGGCAGACGGTGAGGCCCTCGGTC
ACACCCTGGCCCAGCGTCTGCTGGCGGCTGGTGCCGACGTTATCCTGGCCGAGGTCTACCGGGCATGA

Protein sequence :
MKQLIDMAARTLKIATRKSPLALWQANFVKDRLEALYPELQVELVPMSTQGDKILDTPLAKVGGKGLFVKELETAMLEGR
ADIAVHSMKDVPVEFPEGLGLHTICEREDPRDAFVSNRFSQIEALPQGAVVGTSSLRRQCQLRAARPDLVIRDLRGNVNT
RLAKLDAGEYDAIILAAAGLKRLEMAHRITAFIEPEQSLPANGQGAVGIECRLDDHELHTLLAPLEHAETRIRVLTERAM
NRALQGGCQVPIGAYALVQGDEVWLRGLVGSPDGSQVIHDEIRGPLADGEALGHTLAQRLLAAGADVILAEVYRA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-85 63
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-85 63