Gene Information

Name : cadB (ASA_3142)
Accession : YP_001142884.1
Strain : Aeromonas salmonicida A449
Genome accession: NC_009348
Putative virulence/resistance : Virulence
Product : lysine/cadaverine antiporter
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0531
EC number : -
Position : 3399594 - 3400928 bp
Length : 1335 bp
Strand : -
Note : antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein

DNA sequence :
ATGTCCCTAGATACGAGCAAGAAGATTGGCCTTATCGCCTGTACTGGTGTGGTGGCCGGCAACATGATGGGGAGCGGCAT
AGCGCTGCTGCCTTCGGCACTGGCTACCATAGGTTCCATTTCCATTTTCAGCTGGGCTATCTGTCTGGTGGGTGCCATGG
GCCTGGCCTTCGTGTTTGCCCGTCTCGCCACCAAGAACCCGCAAGAGGGTGGCCCCATTGCGTACGCTGGCGAGATCTCC
CCCGTGTTCGGTTTCCAGACCGGTGTGCTCTATTACCATGCCAACTGGATCGGCAACCTGGCCATCGCCATTACCGGCGT
CTCCTACCTGTCGGTCTTCTTCCCCATTCTCAACAACCCTATCCCGGCGGCCATCGCCACCATAGCTGCGGTCTGGATCT
TCACCTTCGTCAACCTGCTCGGCGGTAGCTGGGTGAGCCGACTCTGTACTCTGGGTCTGGTGCTGATCCTGCTGCCTGTG
GTGGGTACTGCCGTGATGGGGTGGGGGCATTTTGATACCAGCGTCTACAGCCAGAACTGGAACACCACCAGCGGCAGCGA
CCTGCATGCGGTCATCAGTGCCGTGCTCATCTGTCTCTGGTCTTTCGTCGGCGTGGAATCCGCCGCCGTCTCTTCCGGCA
TGGTGAAGAACCCCAAGCGCACCGTCCCCCTCGCTACCATGCTGGGCACAGGTATCGCGGGTGTTATCTACATCCTCTCT
ACCCAGGTGATCAGCGGCATGTTCCCGGCCGGTGAAGTGGCGGCCTCCGGCGCACCGTTTGCCATGGCCTCCTCCGCCAT
CTTTGGCAACTGGTCTGCGCCGTTCGTCTCTGCCTTTACCGCTTTGGCCTGTTTCACCTCGCTGGGCTCCTGGATGATGC
TGGTGGGCGAGGCGGGCAAGCGTGCCGCCAACGACGGCAACTTCCCGAAAATCTACGGTGAGCTGGACAAGAACGGTGTG
GCCAAGAAGGGCCTGATCCTCGGCTCTCTCAAGATGACTGCGCTGATGATTGGCCTGACCGCCTTTACCTCCCGGTCCGC
TCACGCTGCCGATCTGTTCAACGTGCTGACCACGGATGCTGTGCTGCTGACCATGCTGCCCTACTTCTACTCCAGCATTA
ACCTCATTCGCTTCGAGGGCATGACCTCCCGCAGCATAGGCACCATGATTTTCTCCGGCGTCGCCTGTGTCTTCTGTCTG
GTGGCCCTGATGGGCGCCAAGGGGTCAAACCTCACTGCCACCTTCGTGGTGTCGCTCATCATTCTGATGTTCTACGCCAA
AAAACAGGGGCTGCGTCAACACGACGCCCTGCTCAAAGAGCAAGCCAGCCACTAA

Protein sequence :
MSLDTSKKIGLIACTGVVAGNMMGSGIALLPSALATIGSISIFSWAICLVGAMGLAFVFARLATKNPQEGGPIAYAGEIS
PVFGFQTGVLYYHANWIGNLAIAITGVSYLSVFFPILNNPIPAAIATIAAVWIFTFVNLLGGSWVSRLCTLGLVLILLPV
VGTAVMGWGHFDTSVYSQNWNTTSGSDLHAVISAVLICLWSFVGVESAAVSSGMVKNPKRTVPLATMLGTGIAGVIYILS
TQVISGMFPAGEVAASGAPFAMASSAIFGNWSAPFVSAFTALACFTSLGSWMMLVGEAGKRAANDGNFPKIYGELDKNGV
AKKGLILGSLKMTALMIGLTAFTSRSAHAADLFNVLTTDAVLLTMLPYFYSSINLIRFEGMTSRSIGTMIFSGVACVFCL
VALMGAKGSNLTATFVVSLIILMFYAKKQGLRQHDALLKEQASH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadB AAL67382.1 cadaverine/lysine antiporter Not tested PAI II CFT073 Protein 3e-131 69
cadB NP_756989.1 lysine/cadaverine antiporter Not tested PAI II CFT073 Protein 4e-131 69
unnamed CAD66196.1 putative lysin/cadaverin transporter Virulence PAI III 536 Protein 1e-125 65

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadB YP_001142884.1 lysine/cadaverine antiporter VFG1671 Protein 8e-126 65