Gene Information

Name : topB (ASA_0267)
Accession : YP_001140206.1
Strain : Aeromonas salmonicida A449
Genome accession: NC_009348
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 283967 - 285937 bp
Length : 1971 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGACTCTTTATCGCCGAGAAGCCCAGTCTTGGCCGAGCCATTGCCGATGTGTTGCCCAAGCCCCACAAGAAGGGGGA
CGGTTTCATCGAAACTGCCGCGGGGGATGTGGTGACCTGGTGCATCGGCCACCTGCTGGAGCAGGCCGAGCCCGATGCCT
ACGACGCCGCCTTCAAGCAGTGGCGCATGGAGCAACTGCCCATCATCCCCGCCCAGTGGCAGCTGGTGGCCAAGCCCAAG
ACCAAGACCCAGCTCACCGTCATCAAGCGGCTGATCAAGCTGGCCGACTGCGTGGTGAATGCCGGTGACCCGGACAGGGA
AGGGCAACTGCTGGTGGACGAGGTGATCGACTTTCTCGGTTACCCCAAGACCAGACCGGTGCAGCGCTGCCTTATCAGCG
ATCTCAATCCGCCGGCGGTGCGCCGTGCCCTCGACAAGCTCAGAGACAACAAGGAGTTCGTGCCGCTGGCGGTATCGGCA
CTGGCCCGCAGCCGTGCCGACTGGCTCTATGGCATCAACATGACCCGGGCTTACACCCTGCTAGGTCGCAAGGGCGGTTG
CAGCGAACTGCTGTCGGTCGGTCGGGTACAGACCCCGCTGTTGGGGCTGGTGGTGCGGCGGGATCTGGAGATAGAGGCCT
TCGTACCCAAGCCCTTCTATGAGGTGCTGGCCCATCTGGTGACCGACGGCAACGAGCGCTTCAGCGCCAAGTGGCTGCCC
TCCGAGGCCTGCCTGCCCTGGCAGGATGAGGAGGGGCGGGTGCTCAACCGGGCGCTGGCGGAGAAAGTGGTCAGTCGCAT
CAATGGCCAACCAGCATCGGTAGAAGAGGTAGAGGAGCAGGCCCGCAAGCAGGCAGCACCGCTGCCCTACAACCTCTCCA
GTTTGCAGATCGATGCTGCCAAGCGCTTTGGCATGGATGCCAAGCGAGTGCTGGATGTGTGTCAGGGGCTCTACGAGCGC
CACAAGCTCATCACTTATCCCAGATCCGACAGCCGTCACCTGCCCAGCGAACACTTCAATCGGGCTGCCCAGGTACGGGA
GGCCATCGCCGCCACTGCGCCGGCACTCGCCAGGGCGGTGAGCGAGGCGGACGGCAAGATCCGTAGCAAGGCGTGGAATG
ACAGCAAGGTGGATGCCCACCACGCCATCATCCCCACCGAGAAGCGTGGCAACGAGAGCAGCCTCAGCGGCGATGAGGCC
AAAATCTACGGTCTGGTGGCGCGCCAATACCTGCTGCAGTTCTACCCGCCGTTCGAGTACAACGACAGCAAGGTGCTGCT
GCGTATCGCGGGTGGCCTGTTCCAGGCCAAGGCGCGGCGGATCCTCAAGGCAGGCTGGAAGGCGCTGCTGGGGGTCGAAG
AAGATGACGACGAAGAGAAAGCCGGTACCCTGCCCGCCCTGAAAGAGGGAGAGCAACTGCTGTGCGAGCGCGGTGAGCTG
CTGGAGAAGATGACCCAGGCGCCCAAGTCGTTCACCGACGCCACCCTGCTGGCCGCCATGACCGGCATAGCCCGCTACGT
GCAGGATCCCGAGATCCGCAAGACCCTGCGCGAAACGGACGGTCTTGGCACCGAGGCGACCCGGGCCGGCATCATAGACC
TGCTGTTCAGGCGTCGTTTTCTGGTGCGCCAGGGCAAGAGCATCAAGGGCACGCCCACTGGACGGGCACTGATCCTGGCT
CTGCCCACCACCGCCACCACGCCGGACATGACGGCTCTGTGGGAGCAGAGCCTGGGCCAGATTGCCGAGCGGCACGCCAG
CTATCAGCAATTTATGGGGCCACTGACAGATCAGTTGAACGCCTTGATTGAGGGAGCCCGGCAGGATTCCGGTGCCAGCT
TCAGCGCCCTGCCCAAGGCGGTGCCGGGGGCCGGCAAGCCGCATTTTACCCGTCGCAAGAGCAGTGCAGGCACCACTGGC
ACTCCTCGCAAGAGTGCCGGCAAGCGCCCGGCCAAGAGCAAGGCGACCTGA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHKKGDGFIETAAGDVVTWCIGHLLEQAEPDAYDAAFKQWRMEQLPIIPAQWQLVAKPK
TKTQLTVIKRLIKLADCVVNAGDPDREGQLLVDEVIDFLGYPKTRPVQRCLISDLNPPAVRRALDKLRDNKEFVPLAVSA
LARSRADWLYGINMTRAYTLLGRKGGCSELLSVGRVQTPLLGLVVRRDLEIEAFVPKPFYEVLAHLVTDGNERFSAKWLP
SEACLPWQDEEGRVLNRALAEKVVSRINGQPASVEEVEEQARKQAAPLPYNLSSLQIDAAKRFGMDAKRVLDVCQGLYER
HKLITYPRSDSRHLPSEHFNRAAQVREAIAATAPALARAVSEADGKIRSKAWNDSKVDAHHAIIPTEKRGNESSLSGDEA
KIYGLVARQYLLQFYPPFEYNDSKVLLRIAGGLFQAKARRILKAGWKALLGVEEDDDEEKAGTLPALKEGEQLLCERGEL
LEKMTQAPKSFTDATLLAAMTGIARYVQDPEIRKTLRETDGLGTEATRAGIIDLLFRRRFLVRQGKSIKGTPTGRALILA
LPTTATTPDMTALWEQSLGQIAERHASYQQFMGPLTDQLNALIEGARQDSGASFSALPKAVPGAGKPHFTRRKSSAGTTG
TPRKSAGKRPAKSKAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-109 43
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-109 43
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-109 43
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 2e-103 42
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 7e-102 42
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 4e-92 41
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 1e-103 41