Gene Information

Name : fliI (ASA_1340)
Accession : YP_001141190.1
Strain : Aeromonas salmonicida A449
Genome accession: NC_009348
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 1397366 - 1398697 bp
Length : 1332 bp
Strand : +
Note : involved in type III protein export during flagellum assembly

DNA sequence :
ATGAGCGGCTCGTTACTCACTCGGTTGCAAGGGTATCGGGTCCGCGATACCGCGCCCAAGCCGCCCGTCGCCGGTAAATT
GACCCGGGTGGTGGGACTCACGCTGGAGGCCATTGGCTGCCGCGCGGCCATCGGTGCCCTCTGTCGCATCGATACCCAGG
ATGGCGAGTTGGAGGCCGAGGTGGTGGGCTTTTCTGGTGATCGCCTGTTCCTGATGCCAAGTGAACAGCTCAAGGGGGTC
ATTCCTGGTGCCCGTGTGGTGCCCATGACCGAAGAGCACGGCATTCCGGTCGGCATGAATCTGCTTGGGCGGGTCATCGA
CGGCATAGGCCAGCCGCTGGACGGGCTTGGTCCCATCCTCTCGTCCCAGACGGTGCAATTTGCCCAGCACCGTATCAACC
CGCTCTCCCGTCGCCCCATCCATCAGCCGATGGACGTAGGGGTGCGCGCCATCAATGCCGTGCTGACGGTAGGGCAGGGC
CAGCGGATGGGACTGTTTGCCGGTTCCGGCGTCGGCAAATCCGTGTTGCTCGGCATGATGACACGCGGCTCGGTGGCGGA
TGTGGTGGTGGTGGGCCTCATCGGTGAACGGGGCCGGGAAGTGAAAGAGTTTATCGAGGACATATTGGGGGAGGAGGGGC
GAGCCCGCTCCGTGGTGGTGGCGGCACCGGCCGATGCCTCACCCCTGATGCGTCTCAAGGGGTGCGAGACGGCGCTCGCC
ATCGCCGAGTATTTTCGCGATCAGGGCCTCAATGTGCTGCTGCTGATGGACTCCCTTACCCGCTATGCCCAGGCCCAGCG
GGAAATCGCACTGGCGGTGGGTGAGCCGCCGGCGACCAAGGGCTATCCGCCGTCGGTCTTTGCCAAATTACCGGCGCTGG
TGGAGCGAGCAGGCAACGGTAGCGATGGTCAGGGCTCCATTACGGCGTTTTTCACCGTCTTGACCGAGGGGGATGACTTG
CAGGATCCCATCGCCGATGCGGCGCGGGCCATCCTCGACGGCCACATAGTCCTGTCGCGGGAGCTGGCCGATGCAGGCCA
CTATCCGGCCATCGATATCGAAAAATCCATCAGTCGTGTCATGCCCATGGTCACCTCACCCGAACACATGGATTTGGCGC
GCACCCTAAAGCAGTTTTACTCCCTCTATCAGCAGAACCGGGATCTCATTACCATAGGCGCTTACAGTCAGGGGTCTGAC
CCTCGCATCGACCGTGCCATCGTTCACAAACCTTATCTGGATCAGTTCTTGCAACAGGGTATGCGCGAGGTCATTCACTA
TGATGAGGGCCTGCAATCCCTGCAACTGGTGGCCATGCCACTGATGCGTTGA

Protein sequence :
MSGSLLTRLQGYRVRDTAPKPPVAGKLTRVVGLTLEAIGCRAAIGALCRIDTQDGELEAEVVGFSGDRLFLMPSEQLKGV
IPGARVVPMTEEHGIPVGMNLLGRVIDGIGQPLDGLGPILSSQTVQFAQHRINPLSRRPIHQPMDVGVRAINAVLTVGQG
QRMGLFAGSGVGKSVLLGMMTRGSVADVVVVGLIGERGREVKEFIEDILGEEGRARSVVVAAPADASPLMRLKGCETALA
IAEYFRDQGLNVLLLMDSLTRYAQAQREIALAVGEPPATKGYPPSVFAKLPALVERAGNGSDGQGSITAFFTVLTEGDDL
QDPIADAARAILDGHIVLSRELADAGHYPAIDIEKSISRVMPMVTSPEHMDLARTLKQFYSLYQQNRDLITIGAYSQGSD
PRIDRAIVHKPYLDQFLQQGMREVIHYDEGLQSLQLVAMPLMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 8e-86 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 9e-87 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-87 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-87 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-85 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-86 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-87 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-85 50
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 8e-85 50
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 4e-85 50
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-75 50
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 5e-75 50
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-75 50
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 2e-75 50
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-75 50
lscN AAO18044.1 LscN Virulence TTSS locus Protein 2e-81 48
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-77 48
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 7e-77 48
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-66 47
escN AAK26715.1 EscN Virulence LEE Protein 6e-79 47
ECs4568 NP_312595.1 EscN Virulence LEE Protein 2e-79 47
escN AAL57542.1 EscN Virulence LEE Protein 6e-79 47
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-79 47
escN CAC81862.1 EscN protein Virulence LEE II Protein 3e-79 47
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-79 47
escN AAC31513.1 L0034 Virulence LEE Protein 1e-79 47
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-79 47
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 4e-79 47
escN AAC38383.1 EscN Virulence LEE Protein 6e-80 47
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-79 47
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-77 47
escN NP_290268.1 hypothetical protein Virulence LEE Protein 2e-79 47
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-68 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 1e-68 46
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-66 45
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-67 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 1e-72 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-64 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-64 45
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 6e-70 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-70 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-70 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 7e-70 44
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 5e-59 41
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-58 41
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-58 41
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-58 41
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-58 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_001141190.1 flagellum-specific ATP synthase VFG1254 Protein 7e-119 64
fliI YP_001141190.1 flagellum-specific ATP synthase VFG2331 Protein 9e-107 63
fliI YP_001141190.1 flagellum-specific ATP synthase VFG2499 Protein 1e-119 63
fliI YP_001141190.1 flagellum-specific ATP synthase VFG0515 Protein 1e-75 50
fliI YP_001141190.1 flagellum-specific ATP synthase VFG0192 Protein 2e-84 49
fliI YP_001141190.1 flagellum-specific ATP synthase VFG0048 Protein 1e-84 49
fliI YP_001141190.1 flagellum-specific ATP synthase VFG0390 Protein 5e-84 48
fliI YP_001141190.1 flagellum-specific ATP synthase VFG0812 Protein 8e-80 47
fliI YP_001141190.1 flagellum-specific ATP synthase VFG0730 Protein 4e-80 47
fliI YP_001141190.1 flagellum-specific ATP synthase VFG2144 Protein 8e-80 46
fliI YP_001141190.1 flagellum-specific ATP synthase VFG2459 Protein 1e-62 42
fliI YP_001141190.1 flagellum-specific ATP synthase VFG1778 Protein 6e-62 42
fliI YP_001141190.1 flagellum-specific ATP synthase VFG0555 Protein 6e-59 41