Gene Information

Name : leuS (cgR_2905)
Accession : YP_001139827.1
Strain : Corynebacterium glutamicum R
Genome accession: NC_009342
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3222788 - 3225646 bp
Length : 2859 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACTAACCCGAGCGAAGGCACCACTCCCCTGGCGTTCCGTTATACCCCGGAACTCGCCAACAAGATCGAAGGTGAGTG
GCAGAATTACTGGACTGACAACGGCACATTCAACGCACCCAACCCAGTGGGTGATTTAGCGCCTGCGGACGGTAAAGCAC
TTCCTGAGGACAAGCTCTTTGTCCAGGATATGTTCCCGTACCCATCCGGAGCTGGCCTGCACGTAGGCCACCCACTCGGT
TACATCGCAACGGATGTTTTCGCCCGCTACAACCGCATGCTGGGCAAGAACGTTCTGCACACCTTGGGCTATGACGCCTT
CGGACTGCCAGCAGAGCAGTACGCGATCCAAACCGGTACACACCCACGCACCACCACCATGGCCAACATTGAGAACATGA
AGCGCCAGCTCGGTGCGCTGGGTCTTGGCCATGATTCCCGTCGTGCGGTGGCCACCACGGATCCTGAGTTCTACAAGTGG
ACTCAGTGGATCTTCCTGCAGATTTTCAATTCGTGGTTCGATGCAGAGCAGCAGAAGGCACGTCCCATCAGTGAGCTGAT
TCCGTTGCTGGAGTCCGGCGAGCTGAAGACTAAGGACGGGGCGGATTACAACGCGCTGGGAGACGTCGAAAAGCAAAAAG
CGGTGGATGACTACCGCCTTGTTTATCGCTCGAACTCCACCGTGAACTGGTGCCCAGGCTTGGGCACCGTGTTGGCAAAC
GAGGAAGTGACCGCGGACGGCCGTTCCGAGCGTGGCAATTTCCCCGTTTTCCGTAAGAATTTGTCCCAGTGGATGATGCG
CATTACCGCGTACTCGGATCGTCTGATCGATGATCTGGAGCTGCTCGATTGGACTGAGAAGGTCAAGTCCATGCAGCGTA
ATTGGATTGGCCGTTCCCGCGGCGCTGAAGTTGATTTCAGTGCAGAGGGCGAAACCGTCACCGTGTTTACCACCCGCCCA
GATACCCTGTTCGGCGCGACCTACATGGTTCTTGCACCTGAGCATGAGCTGGTCGACGTGCTGCTGGAGAAGGCTGGTTC
CTACGAGGGCGTTGATGCCCGTTGGACCAATGGCCAGGCGAGCCCTGCGGAAGCTGTCGCTGCATACCGCGCCTCCATCG
CCGCGAAGTCCGACCTGGAGCGTCAGGAAAACAAGGAAAAGACCGGCGTCTTCCTGGGCGTTTACGCGACCAACCCAGTC
AACGGCGATCAGATCCCAGTGTTCATCGCTGACTACGTTCTGACCGGCTACGGCACCGGCGCCATCATGGCGGTTCCTGC
TCACGACGAGCGCGACTACGAATTCGCCACCGTTTTGGGTCTGCCTATCAAGGAAGTTGTCGCAGGTGGCAACATCGAAG
AGGCTGCTTTCACCGAATCTGGCGAAGCAGTCAACTCTGCCAACGACAACGGCCTGGACATCAACGGCCTTGCCAAGGAT
GAGGCAGTTGCAAAGACCATCGAATGGTTGGAAGAAAAGGAACTTGGCCGCGGCACCATCCAGTACAAGCTGCGCGACTG
GCTGTTCGCCCGCCAGCGTTACTGGGGCGAGCCTTTCCCAATCGTCTACGACGAAAACGGCCAGGCACACGCTCTGCCAG
ACTCCATGCTTCCAGTCGAGCTGCCAGAGGTAGAGGACTACAAGCCTGTCTCCTTCGACCCTGAAGACGCAGACTCCGAG
CCTTCCCCACCACTGGCTAAGGCCCGCGAATGGGTTGAGGTGGAACTCGATCTCGGCGACGGCAAGAAGAAGTACACCCG
CGACACCAACGTCATGCCACAGTGGGCAGGTTCCTCCTGGTACCAGCTGCGCTACGTCGATCCAAGCAACGATGAGCAGT
TCTGCAACATCGAAAACGAACGCTACTGGACCGGCCCACGCCCAGAAACCCACGGACCAAATGATCCAGGTGGCGTAGAC
CTCTACGTCGGCGGTGTTGAGCACGCAGTTCTCCACCTGCTCTACGCACGTTTCTGGCACAAGGTCCTCTTCGACCTGGG
CCACGTCTCCTCCAAGGAGCCATACCGTCGCCTGTACAACCAGGGCTACATCCAGGCCTTCGCCTACACCGATTCCCGTG
GCGTCTACGTGCCTGCCGATGATGTCGAAGAGAAGGACGGAAAGTTCTTCTACCAGGGCGAAGAAGTCAACCAGGAATAC
GGAAAGATGGGCAAGTCCCTGAAGAACGCCGTTGCCCCAGACGATATCTGCAACAACTTCGGTGCTGACACCCTGCGCGT
TTATGAGATGGCCATGGGACCTTTGGACACCTCCCGTCCATGGGCAACCAAGGACGTCGTCGGTGCGCAGCGCTTCCTCC
AGCGTCTGTGGCGTCTCGTCGTCGATGAAAACACCGGCGAAGTGCTCACTCGCGATGAAGTCCTCACCGACGATGACAAC
AAGCAACTGCACCGCACCATCGCAGGCGTCCGCGACGACTACACCAACTTGCGCGTTAACACCGTGGTTGCCAAGCTCAT
CGAATACGTCAACTACCTGACCAAGACATACCCAGACACCATCCCAGCTGGCGCAGTCCTGCCACTGATCGTCATGGTCT
CCCCTGTCGCACCACACATCGCGGAGGAACTCTGGAAGAAGCTCGGCCACGACGACACCGTCACCTACGAACCATTCCCC
ACCTTTGAGGAAAAATGGCTCACCGACGATGAAATCGAACTGCCAGTCCAGGTCAACGGCAAGGTCCGCGGTCGCATCAC
CGTTGCAGCCGACGCCAGCCAGGAGCAGGTCATCGAGGCAGCGCTTGCCGACGAGAAGGTGCAGGAGCAAATCTCCGGCA
AGAACCTGATCAAGCAGATCGTTGTCCCTGGCCGCATGGTCAACCTTGTGGTGAAGTAA

Protein sequence :
MTNPSEGTTPLAFRYTPELANKIEGEWQNYWTDNGTFNAPNPVGDLAPADGKALPEDKLFVQDMFPYPSGAGLHVGHPLG
YIATDVFARYNRMLGKNVLHTLGYDAFGLPAEQYAIQTGTHPRTTTMANIENMKRQLGALGLGHDSRRAVATTDPEFYKW
TQWIFLQIFNSWFDAEQQKARPISELIPLLESGELKTKDGADYNALGDVEKQKAVDDYRLVYRSNSTVNWCPGLGTVLAN
EEVTADGRSERGNFPVFRKNLSQWMMRITAYSDRLIDDLELLDWTEKVKSMQRNWIGRSRGAEVDFSAEGETVTVFTTRP
DTLFGATYMVLAPEHELVDVLLEKAGSYEGVDARWTNGQASPAEAVAAYRASIAAKSDLERQENKEKTGVFLGVYATNPV
NGDQIPVFIADYVLTGYGTGAIMAVPAHDERDYEFATVLGLPIKEVVAGGNIEEAAFTESGEAVNSANDNGLDINGLAKD
EAVAKTIEWLEEKELGRGTIQYKLRDWLFARQRYWGEPFPIVYDENGQAHALPDSMLPVELPEVEDYKPVSFDPEDADSE
PSPPLAKAREWVEVELDLGDGKKKYTRDTNVMPQWAGSSWYQLRYVDPSNDEQFCNIENERYWTGPRPETHGPNDPGGVD
LYVGGVEHAVLHLLYARFWHKVLFDLGHVSSKEPYRRLYNQGYIQAFAYTDSRGVYVPADDVEEKDGKFFYQGEEVNQEY
GKMGKSLKNAVAPDDICNNFGADTLRVYEMAMGPLDTSRPWATKDVVGAQRFLQRLWRLVVDENTGEVLTRDEVLTDDDN
KQLHRTIAGVRDDYTNLRVNTVVAKLIEYVNYLTKTYPDTIPAGAVLPLIVMVSPVAPHIAEELWKKLGHDDTVTYEPFP
TFEEKWLTDDEIELPVQVNGKVRGRITVAADASQEQVIEAALADEKVQEQISGKNLIKQIVVPGRMVNLVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-158 49