Gene Information

Name : cgR_2348 (cgR_2348)
Accession : YP_001139255.1
Strain : Corynebacterium glutamicum R
Genome accession: NC_009342
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2584309 - 2585469 bp
Length : 1161 bp
Strand : -
Note : catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine

DNA sequence :
TTGTCTTTTGACCCACACACCCAGGGTTTCTCCACCGCATCCATTCACGCTGGGTATGAGCCAGACGACTACTACGGTTC
GATCAACATGCCGATCTACGCCTCCACCACCTTCGCACAGAACGCTCCCAACGATCTGCGCCGCGGCTTTGAATACACTC
GCGTGGGCAACCCCACTATCGTGTCCTTGGAAAAGGCCGTCGCAGCGTTGGAAGGTGCAGAGTATGGTCGTGCATTCTCC
TCCGGCATGGCTGCCACTGACATCCTCTTCCGCGTTCTACTCAAGCCAGGTGACCATATTGTGCTCGGAAACGACGCATA
CGGCGGAACCTTCCGCTTGATCGATACCGTGTTCACCGCGTGGGGAATCACCTACACCGTGGTCGACACCTCTGTGGTTG
ACGAAGTCAAGAATGCCATCCAAGACAATACCAAGCTGATCTGGGTGGAAACCCCCACCAACCCAGCACTGGGGATCACC
GATATCGACGCTGTAGCTAAGCTCACTGAAGGCACCAACGCGAAGCTCGTCGTGGACAACACCTTCGCCTCCCCATACCT
GCAGCAGCCACTGGCTCTCGGCGCACATGCTGTCCTGCACTCCACCACCAAGTACATCGGTGGCCACTCTGACGTCGTAG
GTGGACTCGTAGTCACCAACGATCCGGCTCTCGACGAAGAACTGCTGTTCATGCAGGGCGGCGTTGGCCCAATTCCATCT
GTCTTCGATGCTTACCTCACTGCTCGTGGCTTAAAGACCCTGGCTGTGCGCATGGATCGCCACTGTGACAACGCAGAAAA
GGTGGCAGAATTCTTAGATTCCCGTGACGAGGTTTCCGTAGTTCTCTATCCAGGACTGAAGAACCACCCAGGTCACGAGG
TTGCAGCGAAGCAGATGAAGCGCTTCGGCGGCATGATCTCCGTCCGTTTCGCAGGCGGCGAAGAAGCAGCTAAGAAGTTC
TGTACCTCTACCAAGCTGATCTGTCTGGCCGAGTCCCTCGGTGGCGTGGAATCCCTCCTGGAGCACCCAGCAACCATGAC
CCACCAGTCAGCTGCCGGCTCTCAGCTCGAGGTTCCCCGCGACCTCGTGCGCATCTCCATTGGTATTGAAGACATTGAAG
ACCTGCTCGCAGATGTCGAGCAGGCCCTCAATAACCTTTAG

Protein sequence :
MSFDPHTQGFSTASIHAGYEPDDYYGSINMPIYASTTFAQNAPNDLRRGFEYTRVGNPTIVSLEKAVAALEGAEYGRAFS
SGMAATDILFRVLLKPGDHIVLGNDAYGGTFRLIDTVFTAWGITYTVVDTSVVDEVKNAIQDNTKLIWVETPTNPALGIT
DIDAVAKLTEGTNAKLVVDNTFASPYLQQPLALGAHAVLHSTTKYIGGHSDVVGGLVVTNDPALDEELLFMQGGVGPIPS
VFDAYLTARGLKTLAVRMDRHCDNAEKVAEFLDSRDEVSVVLYPGLKNHPGHEVAAKQMKRFGGMISVRFAGGEEAAKKF
CTSTKLICLAESLGGVESLLEHPATMTHQSAAGSQLEVPRDLVRISIGIEDIEDLLADVEQALNNL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-69 45
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-68 44
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 5e-57 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cgR_2348 YP_001139255.1 cystathionine gamma-synthase BAC0207 Protein 1e-65 42