Gene Information

Name : tpx (cgR_1169)
Accession : YP_001138049.1
Strain : Corynebacterium glutamicum R
Genome accession: NC_009342
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 1277028 - 1277525 bp
Length : 498 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCTAAAACACATTTTCAAGGCAACGAAACTGCTACCTCCGGCGAACTGCCACAGGTCGGCGACAACCTCGCAGAGTT
CAACCTCGTCAACACCGAACTGGGCGAGGTCTCCTCAAAGGACTTCCAGGGCCGCAAGCTTGTCCTGAACATCTTCCCAT
CCGTTGACACCGGCGTTTGTGCAACATCAGTCCGCAAGTTCAACGAGGCAGCAGCAAGCCTGGAAAACACCACCGTGCTG
TGCATCTCCAAGGATCTTCCATTCGCACTGGGCCGTTTCTGCTCCGCAGAAGGCATCGAGAACGTCACCCCAGTATCCGC
ATTCCGTTCCACCTTCGGTGAAGACAACGGCATCGTGCTCGAAGGCTCACCACTTAAGGGGCTTCTTGCACGCAGCGTCA
TCGTCGTCGATGAAAACGGCAAGGTTGCTTACACCCAGTTGGTTGATGAGATCTCCACTGAACCTGATTACGACGCTGCA
CTTGCTGCGCTGAACTAA

Protein sequence : 
MAKTHFQGNETATSGELPQVGDNLAEFNLVNTELGEVSSKDFQGRKLVLNIFPSVDTGVCATSVRKFNEAAASLENTTVL
CISKDLPFALGRFCSAEGIENVTPVSAFRSTFGEDNGIVLEGSPLKGLLARSVIVVDENGKVAYTQLVDEISTEPDYDAA
LAALN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 5e-36 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 4e-36 47
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 1e-35 46
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 7e-36 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001138049.1 thiol peroxidase VFG0087 Protein 1e-36 47