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Name : leuS (Mflv_0853) Accession : YP_001132125.1 Strain : Mycobacterium gilvum PYR-GCK Genome accession: NC_009338 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 886011 - 888860 bp Length : 2850 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGACTGAAACGCCGATCGCACCGCTGGACGACACCCCCCGGTTCCGCTACACCGCGGTGCTCGCCGGCGAGATCGAGCG CGCGTGGCAGCAGCAGTGGGCGGATTCGGGCACGTTCCACGTCGACAACCCGGTCGGCTCTCTCGCCCCGGCCGACGGCA GCGCGGTGCCCGCCGACAAGATGTTCGTGCAGGACATGTTCCCGTACCCGTCGGGGGAGGGCCTGCACGTCGGTCATCCG CTCGGTTACATCGCGACGGACGTCTACGCCCGCTACTACCGGATGACCGGCCGTAATGTGTTGCACGCGTTGGGTTTCGA TGCCTTCGGCCTGCCCGCCGAGCAGTATGCGATCCAGACCGGCACCCATCCGCGCACGCGGACCGAGGCCAACATCGTCA ACTTCCGCCGTCAGCTGGGCCGGCTCGGTCTGGGACACGACTCCCGCCGGAGCTTCGCGACGACCGACGTCGACTACTAC AAGTGGACACAGTGGATCTTCCTGCAGATCTTCAACGCGTGGTTCGACACCGACCAGAACAGGGCCCGCCCGATCCGCGA GCTGATCGCCGAGTTCGAGGCCGGCACCCGACAGGTCGGGGACGGCCGGTCCTGGGCGGACCTCGACGCCGGTGCCCGCG CAGATCTGGTCGACGCCCACCGGTTGGTGTATCTGGCGGATTCCGTGGTGAATTGGTGTCCAGGGCTGGGCACCGTGCTG GCCAACGAGGAGGTCACCGCCGACGGCCGTAGCGAACGCGGCAACTTCCCCGTGTTCCGGAAACGGCTGCGGCAGTGGAT GATGCGCATCACCGCGTACTCCGACCGGCTGCTCGAAGACCTCGATGTGCTGGACTGGCCGGACAAGGTCAAGACCATGC AGCGCAACTGGATCGGCCGTTCGACCGGTGCCGAGGTCCAGTTCTCCACCGCCGCAGGCGATATCGAGGTCTTCACTACC CGGCCCGACACGCTGTTCGGGGCGACGTACATGGTGCTCGCACCCGAGCACGACCTCGTCGACCGCCTGGTCGCTTCGGC GTGGCCCGACGGCACCGACGCGCGCTGGACGTTCGGCGCGGCCACCCCGGCCGAGGCGGTGGCCGCCTACCGCGCCGGTA TCGCGGCCAAATCCGACCTGGAGCGCCAGGAGAACAAGACCAAGACCGGCGTCTTCCTCGGCGCCTATGCGACGAATCCG GCCAACGGGCAGCAGGTTCCGGTGTTCATCGCCGACTACGTGCTGGCCGGCTACGGCACCGGAGCGATCATGGCGGTGCC CAGCGGAGACCAGCGCGACTGGGATTTCGCGACCGAGTTCGGGCTGCCGATCGTCGAGGTCGTCGCCGGCGGCGACGTCA CGGTCGAGGCGTATTCCGGCGACGGCACGATGGTGAACTCCGGCTTCCTCGACGGGATGGACGTCGCGACGGCCAAGCAG GCGATGACCGAGCGGTTGGTCGCCGACGGTCGCGGCCGGGCCCGTGTCGAGTACAAGCTGCGGGACTGGCTCTTCGCCCG GCAGCGCTACTGGGGTGAGCCGTTCCCCGTCGTCTACGACAGCGAGGGGCGCGCCCACGGCCTGCCCGAGGGCATGCTGC CGGTGGAACTGCCTGATGTGCCGGACTATTCGCCGGTGTCGTTCGACCCCGACGACGCCGGCAGCGAACCCTCCCCCCCG CTGGGCAAGGTCACCGACTGGGTGAACGTCGACCTCGACCTCGGTGACGGCCTGAAGCCCTACACCCGCGACACCAACGT GATGCCGCAGTGGGCCGGCAGCTCCTGGTACGAGCTGCGCTACACCGACCCGTACAATTCGGAAGCCCTGTGCGCCAAGG AGAACGAGGCGTACTGGATGGGACCGCGGCCCGCCGAGCACGGGCCCGACGATCCGGGCGGGGTCGACCTGTACGTCGGC GGCGTCGAGCACGCGGTGCTGCACCTGCTGTATTCGCGGTTCTGGCACAAGGTGCTGTACGACCTCGGCCATGTCAGCTC CCGCGAGCCCTACCGGCGGCTGGTGAACCAGGGCTACATCCAGGCGTTCGCGTACACCGACTCCCGTGGGTCCTACGTGC CCGCGGCCGAGGTGATCGAGCGGGACGGGAAGTTCGTCTGGCCGGGCCCCGACGGAGAGACAGAGGTCAACCAGGAGTTC GGCAAGATCGGCAAGAGCCTGAAGAACTCGGTGTCCCCCGACGAGATCTGCGACAACTACGGCGCGGACACCCTGCGGGT CTACGAGATGTCGATGGGTCCGCTGGAGGCGTCGCGACCGTGGGCGACCAAGGACGTCGTCGGCGCCTACCGATTCCTGC AGCGGGTGTGGCGCCTGGTGGTCGACGAGAACACCGGGGAGACCCTCGCGACCGAGGACGCGCTCGACGACGACACGCTG CGGTTGCTGCACCGCACGATCGCGGGCACGGCCGATGATTACGCGTCGCTGCGCAACAACACCGCCGCCGCGAAGCTGAT CGAGTACACCAACCACCTGACCAAGCAGTCGGTGACCGCGCGGGCGGCGTTGGAGCCGTTGGTCCTGATGGTCGCGCCGT TGGCGCCGCACCTGGCCGAGGAGCTGTGGAAGCGGCTCGGCCACGAGGGTTCGCTCGCCCACGGCCCGTTCCCGCTGGCC GACGAGCGGTATCTGGTGGAGGACACCGTCGAGTATCCGGTGCAGGTCAACGGCAAGGTCCGCGGCCGCGTCACGGTGCC GGCGGATGCGCCCGCCGACGCGGTCGAGGCTGCCGCGCTGGCCGAGGAGAAGGTCGTCGCGTTCCTCGACGGCCGGACCC CGAAGAAGGTGATCGTCGTCGCGGGCCGCCTGGTCAACGTCGTCGTCTGA Protein sequence : MTETPIAPLDDTPRFRYTAVLAGEIERAWQQQWADSGTFHVDNPVGSLAPADGSAVPADKMFVQDMFPYPSGEGLHVGHP LGYIATDVYARYYRMTGRNVLHALGFDAFGLPAEQYAIQTGTHPRTRTEANIVNFRRQLGRLGLGHDSRRSFATTDVDYY KWTQWIFLQIFNAWFDTDQNRARPIRELIAEFEAGTRQVGDGRSWADLDAGARADLVDAHRLVYLADSVVNWCPGLGTVL ANEEVTADGRSERGNFPVFRKRLRQWMMRITAYSDRLLEDLDVLDWPDKVKTMQRNWIGRSTGAEVQFSTAAGDIEVFTT RPDTLFGATYMVLAPEHDLVDRLVASAWPDGTDARWTFGAATPAEAVAAYRAGIAAKSDLERQENKTKTGVFLGAYATNP ANGQQVPVFIADYVLAGYGTGAIMAVPSGDQRDWDFATEFGLPIVEVVAGGDVTVEAYSGDGTMVNSGFLDGMDVATAKQ AMTERLVADGRGRARVEYKLRDWLFARQRYWGEPFPVVYDSEGRAHGLPEGMLPVELPDVPDYSPVSFDPDDAGSEPSPP LGKVTDWVNVDLDLGDGLKPYTRDTNVMPQWAGSSWYELRYTDPYNSEALCAKENEAYWMGPRPAEHGPDDPGGVDLYVG GVEHAVLHLLYSRFWHKVLYDLGHVSSREPYRRLVNQGYIQAFAYTDSRGSYVPAAEVIERDGKFVWPGPDGETEVNQEF GKIGKSLKNSVSPDEICDNYGADTLRVYEMSMGPLEASRPWATKDVVGAYRFLQRVWRLVVDENTGETLATEDALDDDTL RLLHRTIAGTADDYASLRNNTAAAKLIEYTNHLTKQSVTARAALEPLVLMVAPLAPHLAEELWKRLGHEGSLAHGPFPLA DERYLVEDTVEYPVQVNGKVRGRVTVPADAPADAVEAAALAEEKVVAFLDGRTPKKVIVVAGRLVNVVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 2e-145 | 48 |
