Gene Information

Name : Mflv_0754 (Mflv_0754)
Accession : YP_001132027.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 774742 - 776328 bp
Length : 1587 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACTGCTGTGTCCGACACCGTTTCCGTCACCACCGGCCCTATCACGGGCAGTTCGAAGGTTTATCGCGAGTTGTCCGA
CGGCGGTCGAGTGCCGTTTCGGCGGGTGCACCTGACCACCGGTGATCACCTCGACCTGTACGACACATCGGGTCCGTACA
CCGACGATACCGCGGTGATCGACCTCGCCGCCGGCCTGCCTGAGCGGTCCGGTGTCGTGCGCGACAGCGGCACTCAGTTG
ATGCGCGCGCGCAAAGGCGAGATCACCGCCGAGATGGCCTTCATCGCAGAGCGCGAGGGGTTGCCCGTCGAGCTGGTCCG
CGACGAGGTAGCCCGAGGCCGAGCTGTAATCCCGGCCAACCACAACCATCCCGAGAGCGAGCCGATGATCATCGGCAAGG
CGTTCGCGGTGAAGGTCAACGCCAACATCGGCAACTCGGCGGTCACGTCCTCGGTGGCCGAGGAGGTCGACAAGATGGTG
TGGGCCACCCGTTGGGGCGCCGATACGATCATGGACCTGTCCACCGGCGCCGACATCCACCTCACTCGCGAGTGGATCCT
GCGTAACTCGCCGGTCCCAGTCGGCACCGTCCCGATCTACCAGGCGCTGGAAAAGGTCGACGGCGATCCCACCCAACTGA
CGTGGAAGGTGTACCGCGACACTGTGATCGAGCAGTGCGAGCAAGGCGTGGACTACATGACCGTCCACGCCGGGGTGCTG
CTGCGCTACATCCCGCTCACCGTGAATCGGGTCACCGGCATTGTGTCGCGCGGCGGGTCGATCATGGCCGCCTGGATGCT
CGCCCATCACACCGAGTCATTCCTCTACACCCACTTCGCCGAACTCTGCGAAATCCTGGCCCGCTACGACGTCACCTTCT
CCCTCGGCGACGGACTGCGTCCGGGGTCGATTGCCGACGCCAACGACGAGGCTCAGTTCGCCGAACTGCGCACCCTCGGT
GAGCTGACCAAAATCGCAAAAGCCCATGGCGTGCAGGTGATGATCGAGGGGCCCGGCCACGTCCCGATGCATAAGATCGT
CGAGAACGTGCGCCTCGAGGAAGAGCTTTGCGAGGAAGCACCGTTCTACACTCTGGGGCCCCTGACCACCGACATCGCAC
CGGCATATGACCACATCACGTCCGCGATCGGCGCGGCGATCATCGCGCAGGCCGGCACTGCGATGCTCTGCTACGTCACG
CCCAAGGAACACCTCGGTCTACCCGACCGCAGCGACGTCAAAACGGGCGTCATCACCTACAAGATCGCCGCGCATGCCGC
CGATCTCGCCAAGGCCCACCCGCGCGCCCAGGAACGGGACGACGCACTGTCCACCGCACGCTTCGAGTTCCGCTGGAATG
ACCAGTTCGCGCTGTCCTTAGATCCCGATAGCGCCTGTGGGTTTCACGACGAGACGCTGCCCGCCGTACCGGCGAAGACT
GCCCACTTCTGTTCCATGTGCGGCCCGAAGTTCTGCTCTATGCGCATCAGCCGCGACGTCCGCGACGCCTACGAAAAGGG
GATGACGGACAAATCGCAAGAGTTTGCCAAGCACGGCAATCGCATCTACCTACCGTTGCATCCGTGA

Protein sequence :
MTAVSDTVSVTTGPITGSSKVYRELSDGGRVPFRRVHLTTGDHLDLYDTSGPYTDDTAVIDLAAGLPERSGVVRDSGTQL
MRARKGEITAEMAFIAEREGLPVELVRDEVARGRAVIPANHNHPESEPMIIGKAFAVKVNANIGNSAVTSSVAEEVDKMV
WATRWGADTIMDLSTGADIHLTREWILRNSPVPVGTVPIYQALEKVDGDPTQLTWKVYRDTVIEQCEQGVDYMTVHAGVL
LRYIPLTVNRVTGIVSRGGSIMAAWMLAHHTESFLYTHFAELCEILARYDVTFSLGDGLRPGSIADANDEAQFAELRTLG
ELTKIAKAHGVQVMIEGPGHVPMHKIVENVRLEEELCEEAPFYTLGPLTTDIAPAYDHITSAIGAAIIAQAGTAMLCYVT
PKEHLGLPDRSDVKTGVITYKIAAHAADLAKAHPRAQERDDALSTARFEFRWNDQFALSLDPDSACGFHDETLPAVPAKT
AHFCSMCGPKFCSMRISRDVRDAYEKGMTDKSQEFAKHGNRIYLPLHP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 9e-139 69
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 6e-139 68
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 6e-139 68