Gene Information

Name : smpB (Mflv_4446)
Accession : YP_001135703.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 4733057 - 4733554 bp
Length : 498 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
GTGGCCAAGAAGCCGAAGTCCGTCAAGGACACCAACAACATGGTCGTCGCGTCCAACCGGAAAGCGCGCCACAACTACTC
GATCCTGGAGACCTACGAGGCCGGTGTCGCGCTGGTGGGCACCGAGGTGAAGAGCCTGCGCGACGGCACGGCCTCGCTGG
CCGACGCGTTCGCCACCGTGGACGACGGCGAGATCTGGCTGCGCAACCTGCACATCCCGGAGTATCACCACGGCAGCTGG
ACCAACCACGCGCCACGGCGCAACCGGAAACTGCTGATGCACCGCAGGGAGATCGACAACCTGGTCGGCAAGATCCGCGA
CGGAAACCTGACGCTTGTGCCGCTGTCGCTGTACTTCACCGGCGGCAAGGTCAAGGTGGAACTGGCCCTCGCGCGAGGCA
AGCAGGCACATGACAAACGTCAGGACATGGCGCGCCGCGACGCCCAGCGGGAGGTAACCCGCGAACTGGGTCGTCGGGTC
AAAGGCATGACGAACTGA

Protein sequence :
MAKKPKSVKDTNNMVVASNRKARHNYSILETYEAGVALVGTEVKSLRDGTASLADAFATVDDGEIWLRNLHIPEYHHGSW
TNHAPRRNRKLLMHRREIDNLVGKIRDGNLTLVPLSLYFTGGKVKVELALARGKQAHDKRQDMARRDAQREVTRELGRRV
KGMTN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 7e-53 66
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 9e-32 49
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 6e-24 42