Gene Information

Name : Mflv_4305 (Mflv_4305)
Accession : YP_001135562.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 4574894 - 4576999 bp
Length : 2106 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGGACTACCACGCGCTGAACGCGATGCTGAATCTGTATGACGCAGACGGCAAGATCCAGTTCGAGAAGGACGTGCAGGC
GGCGCGGGAGTACTTCCTGCAGCACGTCAACCAGAACACGGTGTTCTTCCACAGCCAGGACGAGAAGCTCGACTACCTGA
TCGAGAAGAACTACTACGAGCGCGAGGTGCTCGACCAGTATTCGCGCAACTTCGTCAAGGGGCTGCTCGACCGCGCGTAC
GCAAAGAAGTTCCGCTTCCCGACGTTCGTCGGCGCGTTCAAGTACTACACGTCCTACACGCTGAAGACCTTCGACGGGAA
GCGTTACCTGGAGCGCTTCGAGGACCGCGTGGTGATGGTCTCGCTGACTTTGGCTTCCGGTGACACCACGCTCGCCGAGA
AGCTGGTCGACGAGATCATGGACGGCCGGTTCCAGCCGGCCACGCCGACCTTCCTCAACTCGGGCAAGAAGCAGCGCGGC
GAACCGGTGTCGTGCTTCCTGCTGCGCATCGAGGACAACATGGAGTCCATCGGGCGCTCCATCAACTCGGCGCTGCAGCT
GTCCAAGCGCGGCGGCGGAGTCGCGTTGCTGCTGACCAACATTCGCGAGCACGGCGCCCCGATCAAGAACATCGAGAACC
AGAGTTCCGGTGTCATCCCGATCATGAAGCTGCTGGAGGACTCGTTCTCCTACGCCAACCAGCTCGGCGCACGTCAGGGT
GCCGGCGCGGTGTACCTGCATGCGCACCACCCCGACATCTTCCGGTTCCTCGACACCAAGCGCGAGAACGCCGACGAGAA
GATCCGCATCAAGACGCTCTCGCTGGGCGTCGTCATCCCGGACATCACCTTCGAGCTCGCGAAGAAGAACGAGGACATGT
ACCTGTTCTCGCCGTACGACGTCGAGCGCGTGTACGGGCTCCCGTTCGCCGACATCTCGGTCACCGAGAAGTACTACGAA
ATGGTCGACGACGCGCGGATCCGCAAGACCAAGATCAAGGCCCGCGAGTTCTTCCAGACGCTGGCCGAGTTGCAGTTCGA
GTCGGGTTACCCGTACATCATGTACGAGGACACGGTGAACCGGGCCAATCCCATCGACGGCAAGATCACCCACTCGAACC
TGTGCTCGGAGATCCTGCAGGTCTCCACGCCGTCGCTGTTCAACGAGGACCTGTCGTATGCCAAGGTGGGCAAGGACATC
TCGTGCAACCTCGGCTCGCTCAACATCGCGAAGGCGATGGATTCGCCGGACTTCGCGCAGACCATCGAGGTGTCCATCCG
CGCGCTCACCGCGGTGAGCGATCAGACCCACATCTGGTCGGTGCCGTCGATCGAGCAGGGCAACAACAGCTCCCACGCGA
TCGGTCTCGGCCAGATGAACCTGCACGGTTACCTGGCGCGTGAGCGGATCTTCTACGGCTCCGACGAGGGCGTCGACTTC
ACCAACATCTACTTCTACTGCGTGCTCTACCACGCGCTGCGCGCGTCGAATCGCATTGCGATCGAACGGGGTACGGCGTT
CGGTGGATTCGAGAAGTCGAAGTACAAGTCGGGGGAGTTCTTCGACAAGTACACCGATCAGGTGTGGGAACCCAAGACCG
AGAAGGTGCGCGGGCTCTTCGCCGATGCCGGCATCCGGATTCCCGACCAGGAGGACTGGAAGCAGCTCAAGGCCTCGGTG
CAGGAGCACGGTATCTACAACCAGAACCTGCAGGCCGTGCCGCCGACGGGCTCGATCTCCTACATCAACCACTCGACGAG
CTCGATCCACCCGATCGCCAGCAAGGTCGAGATCCGCAAGGAAGGCAAGATCGGTCGGGTCTACTACCCGGCGCCCTACA
TGACCAACGAGAACCTGGAGTACTACCAGGACGCCTACGAGATCGGCTACGAGAAGGTCATCGACACCTACGCCGCCGCC
ACCCAGCACGTCGACCAAGGGTTGAGCCTGACACTGTTCTTCAAGGACACCGCCACCACCCGCGACGTGAACAAGGCGCA
GATCTACGCGTGGCGTAAGGGCATCAAGACGCTGTACTACATCCGGCTGCGTCAGATGGCCCTGGAGGGCACCGAGGTCG
AGGGCTGCGTCAGCTGCATGCTGTAG

Protein sequence :
MDYHALNAMLNLYDADGKIQFEKDVQAAREYFLQHVNQNTVFFHSQDEKLDYLIEKNYYEREVLDQYSRNFVKGLLDRAY
AKKFRFPTFVGAFKYYTSYTLKTFDGKRYLERFEDRVVMVSLTLASGDTTLAEKLVDEIMDGRFQPATPTFLNSGKKQRG
EPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQSSGVIPIMKLLEDSFSYANQLGARQG
AGAVYLHAHHPDIFRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGLPFADISVTEKYYE
MVDDARIRKTKIKAREFFQTLAELQFESGYPYIMYEDTVNRANPIDGKITHSNLCSEILQVSTPSLFNEDLSYAKVGKDI
SCNLGSLNIAKAMDSPDFAQTIEVSIRALTAVSDQTHIWSVPSIEQGNNSSHAIGLGQMNLHGYLARERIFYGSDEGVDF
TNIYFYCVLYHALRASNRIAIERGTAFGGFEKSKYKSGEFFDKYTDQVWEPKTEKVRGLFADAGIRIPDQEDWKQLKASV
QEHGIYNQNLQAVPPTGSISYINHSTSSIHPIASKVEIRKEGKIGRVYYPAPYMTNENLEYYQDAYEIGYEKVIDTYAAA
TQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 79