Gene Information

Name : nrdF (Mflv_4286)
Accession : YP_001135543.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 4552350 - 4553312 bp
Length : 963 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAACTGATCGACCGTGTCTCGGCCATCAACTGGAACCGCCTGCAGGACGACAAGGACGCCGAGGTGTGGGATCGCCT
CACCGGCAACTTCTGGCTGCCCGAGAAGGTCCCGGTGTCGAACGACATCCCGTCGTGGAACACGCTGACCGCCCACGAGA
AGCAGCTCACGATGCGCGTCTTCACGGGTCTGACGCTGCTCGACACGATCCAGGGCACCGTCGGTGCTGTCAGCCTGATC
CCGGACGCGCTGACCCCCCACGAGGAGGCGGTGTACACCAACATCGCGTTCATGGAGTCGGTGCACGCGCGCAGCTACTC
CAACATCTTCTCGACGCTGTGCTCGACGTCGGAGATCGACGACGCGTTCCGCTGGTCGGAGGAGAACCCGAACCTTCAGC
GCAAGGCCGAGATCGTCATGCAGTACTACAAGGGTGACGAGCCGCTCAAGCGCAAGGTGGCCTCGACGCTGCTGGAGAGC
TTCCTGTTCTACTCGGGCTTCTATCTGCCGATGTACTGGAGCAGCCGGGCCAAGCTGACCAACACCGCCGACATGATCCG
GCTGATCATCCGCGACGAGGCCGTGCACGGTTACTACATCGGCTACAAGTTCCAGAAGGGCTTGGCTCTGGCCGACGATG
CGACCCGCCAGGAGCTCAAGGACTACACCTACGAGTTGCTGTTCGAGCTCTACGACAACGAGGTCGAGTACACCCAGGAT
CTCTACGACGAGGTCGGCCTCACCGAAGACGTCAAGAAGTTCCTGCGCTACAACGCGAACAAGGCGTTGATGAACCTCGG
CTACGAGGCGCTGTTCCCGCGCGACGAGACCGACGTCAACCCGGCGATCCTGTCGGCGCTGAGCCCCAACGCCGACGAGA
ATCACGACTTCTTCTCGGGTTCCGGGTCGAGCTACGTGATCGGCAAGGCCGTCATCACCGAAGACGAGGACTGGGACTTC
TAA

Protein sequence :
MKLIDRVSAINWNRLQDDKDAEVWDRLTGNFWLPEKVPVSNDIPSWNTLTAHEKQLTMRVFTGLTLLDTIQGTVGAVSLI
PDALTPHEEAVYTNIAFMESVHARSYSNIFSTLCSTSEIDDAFRWSEENPNLQRKAEIVMQYYKGDEPLKRKVASTLLES
FLFYSGFYLPMYWSSRAKLTNTADMIRLIIRDEAVHGYYIGYKFQKGLALADDATRQELKDYTYELLFELYDNEVEYTQD
LYDEVGLTEDVKKFLRYNANKALMNLGYEALFPRDETDVNPAILSALSPNADENHDFFSGSGSSYVIGKAVITEDEDWDF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-112 74