Name : thyA (Mflv_4007) Accession : YP_001135265.1 Strain : Mycobacterium gilvum PYR-GCK Genome accession: NC_009338 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 4262227 - 4263027 bp Length : 801 bp Strand : - Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : GTGCCGACCGCCACCCCGTACGAGGATCTGTTGCGCCTGGTGCTCGACACCGGGACCCCGAAGTCCGACCGCACGGGAAC CGGCACCCGCAGTCTGTTCGGGCACCAGATGCGGTACGACCTGAACGCGGGTTTTCCGCTGATCACCACCAAGAAGGTGC ACACCAAGTCGATCGTGTACGAGCTGCTGTGGTTCCTGCGCGGCGATTCCAACGTCCGGTGGCTGCAGGAACGCGGTGTC ACCATCTGGGATGAATGGGCTTCTCCGACAGGCGATCTCGGGCCGGTGTACGGCGTGCAGTGGCGATCCTGGCCGACGCC GTCGGGGGAGCACATCGATCAGATCAGCGCCGCGCTGGACCTCCTCAAGCGTGACCCGGACTCGCGACGCAACATCGTCT CGGCGTGGAACGTGGGCGAGATCCCGCAGATGGCGCTGCCGCCGTGCCACGCGTTCTTTCAGTTCTACGTCGCCGACGGC CGGCTGAGCTGCCAGCTGTACCAGCGCAGCGCCGACCTGTTCCTCGGCGTTCCGTTCAACATCGCCAGCTATGCGCTGCT GACGCACATGATGGCCGCGCAGGCCGGCCTCGGCGTCGGTGAGTTCATCTGGACCGGCGGGGACTGTCACATCTACGACA ACCACGTCGAGCAGGTCACCGAGCAGCTCTCCCGTGATCCGCGTCCCTACCCGGAACTCGTTCTCGCGCCGCGGGATTCG ATCTTCGACTACACCTATGAGGACGTCGTCATCAAGAACTATGAACCGCACCCGGCCATCAAAGCGCCCGTCGCGATATG A Protein sequence : MPTATPYEDLLRLVLDTGTPKSDRTGTGTRSLFGHQMRYDLNAGFPLITTKKVHTKSIVYELLWFLRGDSNVRWLQERGV TIWDEWASPTGDLGPVYGVQWRSWPTPSGEHIDQISAALDLLKRDPDSRRNIVSAWNVGEIPQMALPPCHAFFQFYVADG RLSCQLYQRSADLFLGVPFNIASYALLTHMMAAQAGLGVGEFIWTGGDCHIYDNHVEQVTEQLSRDPRPYPELVLAPRDS IFDYTYEDVVIKNYEPHPAIKAPVAI |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 6e-97 | 72 |