Gene Information

Name : Mflv_3692 (Mflv_3692)
Accession : YP_001134954.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 3938035 - 3940128 bp
Length : 2094 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGACCACGATCGAAGAGATCAACTCCCTCACCCGGCCCAACCACCCGGACGACTGGACGGACCTCGATTCGCGGGCCGT
CGACACCGTCCGGATTCTGGCCGCCGACGCCGTCCAGAAGGTCGGCAACGGACACCCAGGCACGGCGATGAGCCTCGCTC
CGCTGGCCTACACGTTGTTCCAGCGGCAGATGCGGCACGATCCGAGCGACGTGCACTGGCTGGGGCGCGACCGTTTCGTG
CTGTCGTGTGGCCACTCCAGCCTCACTCTCTACATCCAGCTCTACCTCGGCGGGTTCGGTCTGGAGCTCTCCGACATCGA
GGCCCTGCGCACCTTCAAGTCCAAGACGCCCGGCCATCCGGAGTTCCGCCACACCCCGGGGGTCGAGATCACCACCGGCC
CGCTCGGACAGGGTCTGGCCTCCGCGGTCGGTATGGCGATGGCGGCGCGCTACGAGCGCGGGCTGTTCGACCCGGACACC
GCGCCCGGTGAGAGCCCGTTCGACCACCACATCTTCGTCATCGCCTCCGACGGCGACATCGAGGAGGGCGTCACCAGCGA
GGCCTCGTCGCTGGCGGGAACCCAGCAGCTGGGCAACCTGATCGTTTTCTACGACAAGAACCACATCTCGATCGAGCACG
ACACCGACATCGCACTGTCGGAGGACGTCGCAGCCCGGTACCGCGCCTACGGCTGGCACGTCCAGGAGGTCGAGGGCGGC
GAGAACGTCGTCGGCATAGAAGAAGCGGTGCAGGCAGCGAAAGCCGTCACCGACAAGCCGTCGCTGATCTCGGTGCGCAC
GATCATCGGCTATCCGGCGCCGAACAAGATGAACACCGGCGGCGTGCACGGATCGGCACTCGGTGACGACGAGGTGGCCG
AGGTCAAGAAGATCCTGGGCTTCGACCCCGACAAGACGTTCGAGGTCAGCGAGGACGTCATCACCCACACCCGCGGCCTG
GTCGCCCGCGGCAAGGAGGCCCACGAGGCCTGGCAGCAGGAATTCGATGCATGGGCGCAGCGCGAGCCCGAGCGCAAGAA
GCTGCTCGACCGGCTGACCGCCGAGGAGCTGCCCGACGGCTGGGATGCCGACATCACCTACTGGGAGCCGGGTTCCAAGG
CGGTCGCGACGCGCGCCGCGTTCGGTCAGGTACTCAACGACGTCGCACCGAAGTTGCCCGAGCTGTGGGGCGGCTCGGCC
GATCTCGCGGGCAGCAACAACACCACCATCAAGGGCGTGAAATCCTTTGGCCCGCCGTCGATCTCGACCGACGACTTCAG
CGCCGACTGGTACGGCCGGGTGCTGCACTTCGGCATCCGCGAGCACGCGATGGGCTCGATCCTGTCGGGTATCGTGCTGC
ACGGCCCCACCCGGGCGTTCGGCGGCACGTTCCTGCAGTTCTCCGACTACATGCGGCCGGCGGTGCGTCTGGCCTCGTTG
ATGGACATCGACACCATCTACATCTGGACGCACGACTCGATCGGCCTGGGCGAGGACGGACCCACGCATCAGCCGATCGA
GCATCTGGCCGCGTTGCGGGCGATCCCGAACCTGTCGGTGGTGCGGCCCGGCGATCCGAACGAGACCGCCTACGCGTGGA
AGAGCATCATCGCCCGCGGCAACGGGAGCGGCCCGGTCGGTTTCATCCTGACGAGGCAAGGTATCCCCGTGTTGGAGGGC
ACGGACGCCGAGGGAGTGAGCCGCGGCGGTTACGTGCTCGGCGGCGGAAATCCCGCCGATGATGCCGACGTCATCCTGAT
TGCGACCGGTTCTGAACTGCAGCTGGCCGTCGAGGCGAAGAAACTCCTGGCCGACAAGGACATCAACGCAGCCGTGGTCT
CGATGCCGTGCGTCGAGTGGTTCGAGTCGCAGCCCAAGGAGTACCGCGACAGCGTGCTACCGCCGGGTGTGTCGGCCCGG
GTCGCGATCGAGGCCGGCGTGGCGCAGAGTTGGTACAAGCTCGTCGGCGACACCGGCGAGATCATCTCGATCGAGCACTA
CGGCGAGTCCGCGGACGACAAGACGTTGTTCCGCGAGTTCGGTTTCACCCCGGAGGCAGTGGTGGCCGCGGCAGAACGCA
CGATTGAAAATTGA

Protein sequence :
MTTIEEINSLTRPNHPDDWTDLDSRAVDTVRILAADAVQKVGNGHPGTAMSLAPLAYTLFQRQMRHDPSDVHWLGRDRFV
LSCGHSSLTLYIQLYLGGFGLELSDIEALRTFKSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAMAARYERGLFDPDT
APGESPFDHHIFVIASDGDIEEGVTSEASSLAGTQQLGNLIVFYDKNHISIEHDTDIALSEDVAARYRAYGWHVQEVEGG
ENVVGIEEAVQAAKAVTDKPSLISVRTIIGYPAPNKMNTGGVHGSALGDDEVAEVKKILGFDPDKTFEVSEDVITHTRGL
VARGKEAHEAWQQEFDAWAQREPERKKLLDRLTAEELPDGWDADITYWEPGSKAVATRAAFGQVLNDVAPKLPELWGGSA
DLAGSNNTTIKGVKSFGPPSISTDDFSADWYGRVLHFGIREHAMGSILSGIVLHGPTRAFGGTFLQFSDYMRPAVRLASL
MDIDTIYIWTHDSIGLGEDGPTHQPIEHLAALRAIPNLSVVRPGDPNETAYAWKSIIARGNGSGPVGFILTRQGIPVLEG
TDAEGVSRGGYVLGGGNPADDADVILIATGSELQLAVEAKKLLADKDINAAVVSMPCVEWFESQPKEYRDSVLPPGVSAR
VAIEAGVAQSWYKLVGDTGEIISIEHYGESADDKTLFREFGFTPEAVVAAAERTIEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 4e-119 43
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-117 42