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Name : lysS (Mflv_3544) Accession : YP_001134806.1 Strain : Mycobacterium gilvum PYR-GCK Genome accession: NC_009338 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 3776598 - 3779903 bp Length : 3306 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : ATGACCGCAACCCGCCTCGTCAGGGCGCATCCCGAGTCCAGTCACCGGTGGGTGCCCGCGGCGGCCGGCTGGATCGTGGG TGTGATCGCCACGTTGTCCCTGCTGGCGAGCGTGTCACCGCTGGTCCGCTCGATCATCCGCGTTCCCCGCGAGTTCGTCG ACGACTACATCTTCAACTTCCCGGACACGAGCTTCGCGTGGGCGTTCGTGCTGGCGCTGCTCGCGGCCGCGCTCGCTGCC CGCAAACGCATCGCCTGGTGGATCCTGACCGGCTACATGGTGGCCGCGGCCGTCTGGAACGTCACCGGACTGCTCGACGG TGACCGGTGGTTCGAGGACGTCGGCGAGATCATCGGCCTGGGCTTCCACCTTGCCGCCATCGCGTCGCTGCTGTTGGCCC GCAGGGAATTCTGGGCCCGGGTGCGCCCGGGCGCGCTCGTCAAGGCGGCAGTCACCCTGGTCGCGGGCCTGGGCGTCGGC ACGCTGATCGGCTGGGGTCTGCTCGAACTGTTCCCCGGCACCCTGGCCCGGCCTGATCGCTTCTGGTACGCGCTCAACCG GGTCGGCGCCTTCGCGGGGGCGGATGCCGGCGCGTTCTCTGGCCACCCGCACGTGCTGGTCAACGCCCTCCTCGGCCTGT TCGGCGCGATGGCCCTGATGATCGCGGCGGTCGTGCTGTTCCAGTCACAGCGTGCGGACAACGCGCTGACCGGTGAGGAC GAATCCGCCATCCGGGGTCTGCTGGAGCTGTACGGGAAGAACGATTCGCTGGGCTATTTCGCGACGCGTCGCGACAAGGC GGTGGTCTTCGCTCCGAACGGACGGGCCGCGATCACCTACCGGGTCGAGGTCGGCGTGTGCCTGGCCAGCGGCGACCCGG TCGGCGACCCGAAGGCGTGGCCGCAGGCCATCGAGGCGTGGCTGACGTTGTGTGAGACCTACGGGTGGGCGCCGGGTGTC ATGGGCGCCAGCGCGACCGGCGCACAGGCGTTCCGCCAGGCGGGCCTGCACGCGCTGCAACTCGGCGACGAAGCGATCCT GCATCCGGACGATTTCCGTCTCTCCGGACCCGAGATGCGCGCGGTGCGCCAAGCCGTCACCCGCGCTCGACGCGCCGGCG TCGCCGTGCGCTTCCGCAGACACCGCGAGTTGTCACCCGACGAGATGGCCGAGGTGATCGCGCACGCCGACGCCTGGCGT GACACCGAGGACGAGCGCGGATTCTCGATGGCGCTGGGCCGGCTCGGTGACCCCGCCGACGCCGACTGCCTCCTGGTGGA GGCCGTACAGAACGGGACCCAGGTCGTCGCGATGCTGTCGCTGGTGCCGTGGGGCAGCAACGGTGTGTCACTGGACCTGA TGCGGCGTGCCCCCCAATCCCCCAACGGCACCATCGAATTGATGGTCAGCGAGCTGTGCCTGCAGTCCGAGAGCATCGGC ATCAGCCGGATCTCGCTGAACTTCGCGATGTTCCGCTCGGCGTTCGAGCAGGGCGCACAGCTCGGGGCCGGCCCGGTGGC CCGGCTGTGGCGGTGGCTGCTCGTCTTCTTCTCCCGCTGGTGGCAGCTGGAGACGCTGTACCGCTCCAACATGAAGTACC AGCCCGAGTGGGTGCCCCGCTATGCGTGTTACGAGGACGCCCGGCTGGTGCCCAGGGTCGGGGTCGCCTCGGTCATCGCC GAAGGCTTTCTGGTGCTTCCCTTCTCGCGGCGCCACGATCAACCCCACACGGGGCACCACATCGCCGCACCGGGCGACCT GATCGCCACCGGACGCCTGCACAGCGACGGAACGGCACCCGACCGCATCGGGCCCGTGGGCGACGGGGCCGACGACGACG CCGCCCCGCGCCTGCCCGAGCAGGTCCGGGTGCGGATGGCGAAGCTCAGCGCCCTGCAGGACCGGGGCGTCGACGCCTAC CCCGTGGGCAGCCCGCCCAGCCACACCATCGCCGAGGCGATCGCCGCCGAGGAAGGCACCGAGGTCACGGTGTCCGGCCG GGTTCTGCGGGCCCGCGACTACGGTGGTGTGCTCTTCGGTCAGCTACGCGACTGGTCCGCCGAAACCCAGGTGGCGCTGG ACAATTCGGCGCTGCTCGACGGAACCACCACCGACTTCACCCGCACCGTCGACCTCGGCGACCTGATCGAGGTGACCGGC ACGATGGGCCACACCCGGTCGGGTTCGTGGTCGGTGCTGGTGACCCGGTGGCGGTTGATCGGCAAGTGCCTGCGGCCGCT GCCCGACAAGTGGAAGGGGTTGACCGACCAGGAGGCGCGGGTGCGCGCCCGCTACGTCGACCTCGCGGTCAACACCGACG CCCGCGAACTCATCAAGGCCCGCAGCGCCATTCTGCACGCCATCCGCGAAACCCTGGTCGGCAAAGGCTTTCTCGAGGTC GAGACGCCGATCCTGCAGCAGATCCACGGCGGCGCCAACGCGCGTCCGTTCCTGACCCACATCAACGCCTACGACCTGGA CCTGTATCTGCGGATCGCACCCGAGTTGTATCTGAAGAGGCTCTGTGTCGGGGGCGTCGAGCGGGTCTTCGAGCTGGGCC GGGCGTTCCGGAACGAGGGGGTCGACTTCAGCCACAATCCCGAATTCACCCTGCTGGAGGCCTACCAGGCGCACGCGGAC TACACCGTGTGGATCGACGGGTGCCGCGAGCTGATCCAGAACGCGGCCATGGCCGCCAACGGCTCCCACGTGTTCTTCCG TCCGCGCGAGGACGGGGTCCTCGAACCGGTCGACATCTCCGGCCGATGGGCGGTCAAGACGGTTCACGGCGCGGTGTCGG AGGCACTCGGCGAGCACATCGACGTCGACACCGACCTGGCGACGCTGCGCCGCCTCTGCGACAAGGCCGGCATCCCCTAC CTGACGCACTGGGACGCCGGCGCGGTGGTCCTCGAGATGTACGAGCACCTCGTCGAGGACCAGACCACCGAACCCACCTT CTACAAGGACTTCCCGACGTCCGTGTCGCCGCTGACCCGGCCGCACCGCAGCATCCCGGGGGTCGCCGAACGCTGGGACC TCGTCGCGTGGGGGGTCGAGCTCGGCACCGCCTACAGCGAACTGACCGACCCTGTGGAGCAGCGCCGCAGGTTGCAGGAG CAGTCGCTGCTGGCCGCAGGCGGCGACCCGGAGGCGATGGAGCTCGACGAGGACTTCCTGCAGGCGATGGAGTACGCGAT GCCTCCGACCGGAGGCCTCGGAATGGGTGTCGATCGGGTGGTCATGCTGATCACCGGGCGCAGCATCCGCGAGACGCTGC CGTTCCCGCTCGCGAAACCGAGGTAG Protein sequence : MTATRLVRAHPESSHRWVPAAAGWIVGVIATLSLLASVSPLVRSIIRVPREFVDDYIFNFPDTSFAWAFVLALLAAALAA RKRIAWWILTGYMVAAAVWNVTGLLDGDRWFEDVGEIIGLGFHLAAIASLLLARREFWARVRPGALVKAAVTLVAGLGVG TLIGWGLLELFPGTLARPDRFWYALNRVGAFAGADAGAFSGHPHVLVNALLGLFGAMALMIAAVVLFQSQRADNALTGED ESAIRGLLELYGKNDSLGYFATRRDKAVVFAPNGRAAITYRVEVGVCLASGDPVGDPKAWPQAIEAWLTLCETYGWAPGV MGASATGAQAFRQAGLHALQLGDEAILHPDDFRLSGPEMRAVRQAVTRARRAGVAVRFRRHRELSPDEMAEVIAHADAWR DTEDERGFSMALGRLGDPADADCLLVEAVQNGTQVVAMLSLVPWGSNGVSLDLMRRAPQSPNGTIELMVSELCLQSESIG ISRISLNFAMFRSAFEQGAQLGAGPVARLWRWLLVFFSRWWQLETLYRSNMKYQPEWVPRYACYEDARLVPRVGVASVIA EGFLVLPFSRRHDQPHTGHHIAAPGDLIATGRLHSDGTAPDRIGPVGDGADDDAAPRLPEQVRVRMAKLSALQDRGVDAY PVGSPPSHTIAEAIAAEEGTEVTVSGRVLRARDYGGVLFGQLRDWSAETQVALDNSALLDGTTTDFTRTVDLGDLIEVTG TMGHTRSGSWSVLVTRWRLIGKCLRPLPDKWKGLTDQEARVRARYVDLAVNTDARELIKARSAILHAIRETLVGKGFLEV ETPILQQIHGGANARPFLTHINAYDLDLYLRIAPELYLKRLCVGGVERVFELGRAFRNEGVDFSHNPEFTLLEAYQAHAD YTVWIDGCRELIQNAAMAANGSHVFFRPREDGVLEPVDISGRWAVKTVHGAVSEALGEHIDVDTDLATLRRLCDKAGIPY LTHWDAGAVVLEMYEHLVEDQTTEPTFYKDFPTSVSPLTRPHRSIPGVAERWDLVAWGVELGTAYSELTDPVEQRRRLQE QSLLAAGGDPEAMELDEDFLQAMEYAMPPTGGLGMGVDRVVMLITGRSIRETLPFPLAKPR |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 3e-153 | 42 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 3e-153 | 42 |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 9e-153 | 42 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 3e-153 | 42 |
