Gene Information

Name : Mflv_3214 (Mflv_3214)
Accession : YP_001134479.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Resistance
Product : alkylmercury lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.99.1.2
Position : 3411779 - 3412420 bp
Length : 642 bp
Strand : +
Note : cleaves the carbon-mercury bond of organomercuric compounds

DNA sequence : 
ATGCCCAATTTCCTTGACCGCCTGACCATTCCGGAAGAGTCCGGGCTCGACCCGACGATGCTGGTGCCGTTGCTGCGGCT
GCTCGCCGCCGGCGAGCCGGTCACCGTGGAGGCGCTCGCCGCGGCCGTCGGCCTCCCGGTTGACGAGGTGACCCGGCGTC
TGGCCGCGGTACCCGACACCGAATACGACGAGCAGGGCCGCATCGTCGGCCAGGGCCTGACCCTGCGCCCGACCCGCCAC
CGATTCACCGTGGCCGGCCAAGAGCTCTACACCTGGTGCGCCCTGGACACCCTCATCTTTCCCACCATCCTGGACCGGCC
CGCCAGCATCGAATCCGAATCACCCGTCAGCGGGCACCCGATCAGGGTCTCGGTCGGCGAAAACGGTGTCACCAGCGTGC
AGCCCGAGACCGCGGTGGTCTCGCTGGTCAACCCCGACGACCTCACCTCGATCCGGTCCTCATTCTGCAACCAGGTGCAC
TACTTCACCTGCGCGCAGGACGCCGCGCCGTGGCTCGCCGAGCACCCCGAAGGTCAGATCGTCAGCGTCGCTGAGGCCCA
CCAACTCGGCGCAGCCCTGACCACACAAATCCTTACCCAGCTCCATACCCCGCCAACTGCCCACCCCGGCTGCTGCAGCT
GA

Protein sequence : 
MPNFLDRLTIPEESGLDPTMLVPLLRLLAAGEPVTVEALAAAVGLPVDEVTRRLAAVPDTEYDEQGRIVGQGLTLRPTRH
RFTVAGQELYTWCALDTLIFPTILDRPASIESESPVSGHPIRVSVGENGVTSVQPETAVVSLVNPDDLTSIRSSFCNQVH
YFTCAQDAAPWLAEHPEGQIVSVAEAHQLGAALTTQILTQLHTPPTAHPGCCS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0086 NP_763641.1 alkylmercury lyase Not tested SCCpbp4 Protein 1e-45 46
merB BAB47641.1 organomercurial lyase Not tested Type-III SCCmec Protein 1e-45 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mflv_3214 YP_001134479.1 alkylmercury lyase BAC0663 Protein 8e-49 49
Mflv_3214 YP_001134479.1 alkylmercury lyase BAC0654 Protein 8e-49 49
Mflv_3214 YP_001134479.1 alkylmercury lyase BAC0658 Protein 5e-46 46
Mflv_3214 YP_001134479.1 alkylmercury lyase BAC0657 Protein 1e-36 43