Gene Information

Name : Mflv_0246 (Mflv_0246)
Accession : YP_001131528.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 231581 - 234127 bp
Length : 2547 bp
Strand : -
Note : PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: mva:Mvan_0659 ATPase AAA-2 domain protein

DNA sequence :
GTGGACTCGTTCAATCCGACGACCAAGACCCAGGCGGCCCTGACTTCGGCGCTGCAGGCGGCGACAGCCGCGGGCAACCC
GCAGATCACTCCCGCCCACCTGTTGATGGCATTGCTCACCCAGAACGATGGCATTGCCGCACCTCTGCTCGAGGCCGTCG
GTGTCGAACCCGCGACCATCCGCGCCGAGACGCAGCGATTGCTCGACCGGCTGCCCAGCGCAACCGGATCGGCGTCGCAA
CCCCAGCTGTCCCCGCCGGCGATCGCCGCGATCACCGCGGCGACGCATCTGGCCACCGAGATGGACGACGAGTACGTCTC
CACCGAACACCTGTTGGTCGGCCTCGCCACCGGTGACAGCGACGTCGCCAAGGTGCTCACCGGGCACGGCGCCTCACCGC
AGGCGCTGCGGGAGGCGTTCGTCAAGGTCCGCGGCAGCGCCCGGGTCACCAACCCCGATCCCGAGGGCACCTATCAGGCG
CTGGAGAAGTACTCCACCGACCTGACCGCGCGCGCCAGGGAAGGCAAGCTCGACCCGGTCATCGGCCGCGACCACGAGAT
CCGTCGTGTCGTGCAGGTCCTGAGCCGCCGCACCAAGAACAACCCGGTGCTCATCGGCGAACCCGGTGTCGGCAAGACCG
CGATCGTGGAGGGCCTGGCCCAGCGCATCGTCGCCGGCGACGTCCCCGAGAGCCTGCGCGACAAGACCGTCGTCTCGCTC
GACATGGGCTCGATGGTGGCCGGCGCGAAGTACCGCGGTGAGTTCGAGGAGCGGCTCAAGGCCGTCCTCGACGACATCAA
GAACTCGGCCGGACAGATCATCACCTTCATCGACGAGTTGCACACCATCGTCGGCGCCGGTGCCACCGGCGAATCGGCGA
TGGACGCCGGCAACATGATCAAGCCGATGCTGGCCCGCGGCGAGCTGCGGCTGGTGGGCGCGACCACCCTCGACGAGTAC
CGCAAGTACATCGAGAAGGACGCCGCGCTGGAACGACGTTTCCAGCAGGTGCTGGTCGGCGAACCGTCCGTCGAGGACAC
CGTCGGCATCCTGCGCGGGCTCAAGGACCGCTACGAGGTGCACCACGGTGTGCGCATCACCGACTCCTCGCTGGTCGCGG
CGGCCACCCTCAGTGACCGCTACATCACGTCGCGCTTCCTGCCCGACAAGGCCATCGACCTGGTCGACGAGGCGGCGTCG
CGGCTGCGGATGGAGATCGACTCCCGGCCCGTCGAGATCGACGAGGTCGAGCGGCTGGTCCGTCGCCTCGAGATCGAGGA
GATGGCACTCGCCAAGGAGGAAGACGCCGCGTCGAAGGACCGCCTGGAGAAGCTGCGCGCCGAGCTGGCCGACAAGAAGG
AACAACTGGCCGAGCTGACCACGCGCTGGCAGAACGAGAAGAGCGCCATCGACGTCGTCCGCGAACTCAAGGAACAGCTG
GAATCGCTGCGCGGCGAGGCCGACCGGGCCGAGCGTGACGGCGATCTGGCCAAGGCCGCCGAGCTCCGCTACGGACGCAT
CCCCGAGGTCGAGAAGAAGCTCGACGCGGCGCTGCCCCACGCGGAGGCACGCGAGAACGTGATGCTCAAGGAGGAGGTCG
GTCCCGACGACATCGCCGAGGTGGTCGAGGCGTGGACCGGCATCCCGGCCGGCCGCATGCTCGAAGGCGAGACCGCCAAG
CTGCTCCGGATGGAGGAGGAGCTGGGCAAGCGGGTGGTCGGCCAGCGCAAGGCCGTCACCGCGGTCTCCGATGCGGTGCG
CCGGTCGCGGGCCGGTGTCGCCGACCCGAACCGGCCGACGGGCTCGTTCATGTTCCTCGGCCCGACCGGTGTCGGTAAGA
CCGAGCTGGCCAAGGCACTCGCCGAGTTCCTGTTCGACGACGAGCGCGCGATGGTCCGCATCGACATGAGCGAGTACGGC
GAGAAGCACTCGGTGGCTCGCCTGGTCGGTGCGCCTCCCGGCTACGTCGGCTATGACCAGGGCGGTCAGCTGACCGAGGC
GGTGCGGCGGCGTCCGTACACGGTGATCCTGTTCGACGAGATCGAGAAGGCCCACCCGGACGTGTTCGACGTGCTGCTGC
AGGTCCTCGACGAGGGCAGGCTGACCGACGGTCAGGGACGCACGGTCGACTTCCGCAACACCATCCTGATCCTGACGTCC
AACCTCGGCGCCGGCGGTTCCGAGGAGCAGGTGATGGCCGCGGTGCGGGCGGCGTTCAAGCCGGAGTTCATCAACCGGCT
CGACGACGTGATCATGTTCGACGCGCTCGATCCCGAGCAGCTGGTGTCGATCGTCGACATCCAGCTCGAGCAGCTCGCCA
AGCGGCTGGCTCAGCGCAGGCTGACGCTGGAGGTGTCGCTGCCCGCCAAGAAGTGGCTGGCCGAGCGTGGGTTCGACCCG
CTCTACGGCGCGCGGCCGCTGCGGCGGCTGGTGCAGCAGGCCATCGGCGACCAGCTGGCCAGGATGCTGCTGTCGGGTCA
GGTGCACGACGGCGACGTGGTGCCGGTGAACCTCAGTGCGGACGGGGACTCCCTGGTTCTGGGATGA

Protein sequence :
MDSFNPTTKTQAALTSALQAATAAGNPQITPAHLLMALLTQNDGIAAPLLEAVGVEPATIRAETQRLLDRLPSATGSASQ
PQLSPPAIAAITAATHLATEMDDEYVSTEHLLVGLATGDSDVAKVLTGHGASPQALREAFVKVRGSARVTNPDPEGTYQA
LEKYSTDLTARAREGKLDPVIGRDHEIRRVVQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVAGDVPESLRDKTVVSL
DMGSMVAGAKYRGEFEERLKAVLDDIKNSAGQIITFIDELHTIVGAGATGESAMDAGNMIKPMLARGELRLVGATTLDEY
RKYIEKDAALERRFQQVLVGEPSVEDTVGILRGLKDRYEVHHGVRITDSSLVAAATLSDRYITSRFLPDKAIDLVDEAAS
RLRMEIDSRPVEIDEVERLVRRLEIEEMALAKEEDAASKDRLEKLRAELADKKEQLAELTTRWQNEKSAIDVVRELKEQL
ESLRGEADRAERDGDLAKAAELRYGRIPEVEKKLDAALPHAEARENVMLKEEVGPDDIAEVVEAWTGIPAGRMLEGETAK
LLRMEEELGKRVVGQRKAVTAVSDAVRRSRAGVADPNRPTGSFMFLGPTGVGKTELAKALAEFLFDDERAMVRIDMSEYG
EKHSVARLVGAPPGYVGYDQGGQLTEAVRRRPYTVILFDEIEKAHPDVFDVLLQVLDEGRLTDGQGRTVDFRNTILILTS
NLGAGGSEEQVMAAVRAAFKPEFINRLDDVIMFDALDPEQLVSIVDIQLEQLAKRLAQRRLTLEVSLPAKKWLAERGFDP
LYGARPLRRLVQQAIGDQLARMLLSGQVHDGDVVPVNLSADGDSLVLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-107 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mflv_0246 YP_001131528.1 ATPase VFG2076 Protein 1e-111 43
Mflv_0246 YP_001131528.1 ATPase VFG2084 Protein 1e-111 41