Gene Information

Name : Mflv_1654 (Mflv_1654)
Accession : YP_001132924.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Resistance
Product : arsenite-activated ATPase ArsA
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0003
EC number : 3.6.3.16
Position : 1720670 - 1722439 bp
Length : 1770 bp
Strand : -
Note : KEGG: mfa:Mfla_1491 arsenite-activated ATPase (ArsA); TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; SMART: AAA ATPase

DNA sequence : 
GTGAAGTTCCTGGAGGCGCCACCGCGGTTCTTGTTCTTCACCGGCAAAGGCGGGGTGGGCAAGACCTCGATCGCGTGCGC
CGCCGCAATCCACTTGGCCGGCTCTGGCAAGCGGGTCCTGCTGGTCAGCACTGACCCGGCATCGAACGTGGGCCAGGTGC
TCGGTCTGACGATCGGTAACACGATCACCCGGGTTCCTGCCGTGGACGGCCTATCTGCCTTGGAGATCGATCCCGATCAG
GCGGCTGAGGCGTACCGCGAACGCATCATCGGCCCGGTGCGGGGCCTGCTGCCCGCCCCGGAATTGCAGTCGATCACTGA
GCAGCTCTCCGGCTCGTGCACCACCGAGATCGCGTCATTCAACGAATTCACCGAATTGCTCACTGATTCGGATGGTCCCG
TCAAGCAGTTCGACCACGTGCTGTTCGACACCGCCCCAACCGGCCACACCATCCGGCTCCTTCAGCTTCCCGGGTCGTGG
ACCGACTTCCTCGATGCCGGTAAGGGCGACGCATCGTGTCTGGGACCACTGTCCGGGCTCGGAAAGCAGCGGGCTCTCTA
TGCCGGGGCCGTGGACGCACTGGCCGATCCGCAGCGCACCCGCATGGTGCTTGTGGCCCGCGCGCAGCGGTCGGCGCTGA
CCGAAATCGCCCGCACACACGGTGAACTCGCCGCGATCGGTCTCACCCACCAGCACGTCGTGATCAACGGCGTCTTGCCT
GCCTGTGCTGGATCCGGCGATCCACTGGCTGCTGCGATCTATGCGCGCGAACGGGACGCCATCGCCACCATGCCCGACGA
ATTACGGGCGCTCCCACTCGATCAGGTTGACCTCAAGCAGGTCAACATCGTCGGCCTGGAGGCACTCACGACACTTTTCG
AGCCGGACGCGGTGACCCCCGGCACCGACCGGGAAGTGGATTTCGCCGTGGCGGACGCACCGCTGGCGAAGCTGGTCGAC
GAACTCGCCACCAGCGAACACGGTTTGATCATGTGTATGGGTAAGGGCGGCGTGGGCAAGACCACGATCGCCGCTGCGAT
CGCCGTCGCACTCGCAGACCGTGGTCATCCTGTACACCTGACCACGACCGACCCCGCCGGCCACCTCACCGACATGCTGC
ACGGCACCATGGAGAATCTGCACGTCTCGCGTATCGATCCGGCTGAGGCCACCCGCGCTTACCGAGACCATGTGCTTGCC
ACCAAGGGTGCCGCCCTCGACGACCAGGGCCGAGTGATGCTCGAAGAGGATCTCCGCTCGCCGTGCACCGAGGAAGTCGC
TGTGTTCCAAGCATTCTCGCGGGTTATCGCTGAATCGCGACGCAAGTTCGTTGTTGTCGATACCGCACCCACCGGACACA
CATTGTTGCTACTGGATGCCACCGGCTCCTACCACCGCGAGGTGGCGAGGCAGCTGGGCGACCGGCACTTCACCACGCCG
CTGATGCGCCTGCAGGATCCCGATCTCACCAAGGTCATCATCGTCACGCTGGCCGAGACCACCCCGGTTCTCGAAGCGGC
GGGGCTCGAGAGTGATCTCGAGCGCGCGCAGATCCACCCCTGGGCCTGGGTGGTCAACAACTCGACCTCCGCCGCACACC
CCACCGCACCACTGCTGCGCCACCGCGCGGTCGCTGAGCTACCCGAGATCGACAAAGTACGAACCCGGCACGCGGATCGA
CTCGCGGTGGTGCCGCTCCTCGCCGCCGAACCCGTCGGCATTCGAGCCCTGGAGGCACTGACCGGGTCATCGAAGTCCGC
AATGCAGTGA

Protein sequence : 
MKFLEAPPRFLFFTGKGGVGKTSIACAAAIHLAGSGKRVLLVSTDPASNVGQVLGLTIGNTITRVPAVDGLSALEIDPDQ
AAEAYRERIIGPVRGLLPAPELQSITEQLSGSCTTEIASFNEFTELLTDSDGPVKQFDHVLFDTAPTGHTIRLLQLPGSW
TDFLDAGKGDASCLGPLSGLGKQRALYAGAVDALADPQRTRMVLVARAQRSALTEIARTHGELAAIGLTHQHVVINGVLP
ACAGSGDPLAAAIYARERDAIATMPDELRALPLDQVDLKQVNIVGLEALTTLFEPDAVTPGTDREVDFAVADAPLAKLVD
ELATSEHGLIMCMGKGGVGKTTIAAAIAVALADRGHPVHLTTTDPAGHLTDMLHGTMENLHVSRIDPAEATRAYRDHVLA
TKGAALDDQGRVMLEEDLRSPCTEEVAVFQAFSRVIAESRRKFVVVDTAPTGHTLLLLDATGSYHREVARQLGDRHFTTP
LMRLQDPDLTKVIIVTLAETTPVLEAAGLESDLERAQIHPWAWVVNNSTSAAHPTAPLLRHRAVAELPEIDKVRTRHADR
LAVVPLLAAEPVGIRALEALTGSSKSAMQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsA2 YP_001007632.1 arsenical pump-driving ATPase Not tested YAPI Protein 2e-175 64
SH0111 YP_252026.1 arsenical pump-driving ATPase Not tested SCCmec Protein 4e-91 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mflv_1654 YP_001132924.1 arsenite-activated ATPase ArsA BAC0572 Protein 1e-173 63
Mflv_1654 YP_001132924.1 arsenite-activated ATPase ArsA BAC0571 Protein 8e-174 63
Mflv_1654 YP_001132924.1 arsenite-activated ATPase ArsA BAC0030 Protein 8e-174 63