Gene Information

Name : Mflv_1150 (Mflv_1150)
Accession : YP_001132420.1
Strain : Mycobacterium gilvum PYR-GCK
Genome accession: NC_009338
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1191211 - 1192548 bp
Length : 1338 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGACAGGCGTGTCGGGTGCTGTGCCGGTACCTCAGCGAATGTGCAGGCAGGGCGGCCGACCCCGTAGGGTTGGCCCGGT
GATCGACCCGAAGGTGCTGCGAGAAAACCCCGACGCCGTCCGCGCATCACAACAGGCCAGGGGCGAGGATCCCAGTCTGG
TCGACGCGCTCGCCGAGGCCGACTCCGCCCGGCGTGCCGCGATCTCGGCCGCCGACAATCTGCGCGCGGAACAGAAGTCG
GCCAGCAAGGCGATCGGCAAGGCGTCGCCCGACGAACGGCCCGCGCTGCTGGCCGCCGCGAAGGAGCTCTCCGAGAAGGT
CAAGGCCGCCGAGGCCGACCAGGCGGCCGCCGAGGCCGCCTACACCGCGGCGCACATGGCGATCTCGAACGTGATCATCG
ACGGGGTGCCCGCCGGCGGTGAGGACGATTTCGTGGTGCTCGACACCGTCGGTGAACCACGGGTCATCCCCGACGCCAAG
GACCATCTCGAGCTCGGCGAGGCACTGGGGTTGATCGACATGGAGCGCGGGGCCAAGGTGTCGGGGTCGCGCTTCTACTT
CCTCACCGGGTTCGGCGCGCTGCTGCAGCTCGGTCTGTTCCAGCTGGCGGTGCGCACCGCCACCGAGAACGGCTTCACAC
TGATGATCCCGCCGGTGCTGGTCCGGCCGGAGATCATGCGCGGCACCGGGTTCCTGGGCGCACACGCCGACGAGATCTAC
CACCTCGCCGAGGACGATCTGTATCTGGTCGGGACGTCGGAGGTGCCGCTGGCCGGCTACCACTCCGACGAGATCCTCGA
CCTGTCGGGTGGCCCGCTGAGGTACGCCGGCTGGTCGTCGTGCTTCCGGCGCGAGGCGGGTAGCTACGGCAAGGACACCC
GCGGCATCATCCGGGTGCACCAGTTCGACAAGGTCGAGGGCTTCGTCTACTGCCGGCCCGAAGAGGCCGAGGCCGAGCAC
GATCGACTGCTCGGCTGGCAGCGTCAGTTGCTGGCGGCCATCGAGGTGCCCTACCGGGTGATCGACATCGCCGCGGGAGA
TCTGGGGTCGTCGGCGGCACGCAAGTACGACTGCGAGGCGTGGGTGCCGACGCAGCAGACCTACCGCGAGCTGACCTCGA
CGTCGAACTGCACCACGTTCCAGGCGCGGCGACTGGCCGTGCGCTACCGCGATGAGAACGGCAGGCCCCAGACCGCGGCG
ACGCTGAACGGGACGCTGGCCACCACGCGCTGGCTGGTCGCGATCCTGGAGAACCATCAGCAGCCCGACGGCAGCGTGCG
GATCCCCGAGGCGCTGGTGCCCCACGTCGGCACAAACGTGCTCAGACCCAAGAAGTAG

Protein sequence :
MTGVSGAVPVPQRMCRQGGRPRRVGPVIDPKVLRENPDAVRASQQARGEDPSLVDALAEADSARRAAISAADNLRAEQKS
ASKAIGKASPDERPALLAAAKELSEKVKAAEADQAAAEAAYTAAHMAISNVIIDGVPAGGEDDFVVLDTVGEPRVIPDAK
DHLELGEALGLIDMERGAKVSGSRFYFLTGFGALLQLGLFQLAVRTATENGFTLMIPPVLVRPEIMRGTGFLGAHADEIY
HLAEDDLYLVGTSEVPLAGYHSDEILDLSGGPLRYAGWSSCFRREAGSYGKDTRGIIRVHQFDKVEGFVYCRPEEAEAEH
DRLLGWQRQLLAAIEVPYRVIDIAAGDLGSSAARKYDCEAWVPTQQTYRELTSTSNCTTFQARRLAVRYRDENGRPQTAA
TLNGTLATTRWLVAILENHQQPDGSVRIPEALVPHVGTNVLRPKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-46 42