Gene Information

Name : lysS (Cvib_0698)
Accession : YP_001130215.1
Strain : Chlorobium phaeovibrioides DSM 265
Genome accession: NC_009337
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 796910 - 798418 bp
Length : 1509 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGCAGCAAGAACACGAACAGCAAATCTCCCTCAACGACCAGATGCAGCGCCGTCTGGACGAACGCACGCACCTTATGGA
ATCGGGCATCAACCCCTATCCATGCGAATTCGCCGTCACCGCCCACTCCCGTGACATCATTGAAACATTTCAGGAGGAGG
CCAAAACCCCCGTATCAGTTGCGGGGCGCATTATGGCCATCAGAAAAATGGGCAAAGCCTCATTTTTCCACATTCAGGAC
GCCAAAGGCAGAATACAGGTCTACCTGAAAAAAGACGAAGTCGGAGAAACCTCATACAACACATTCAAACTGCTCGACAT
CGGCGACATTGCGGGCGTGAAAGGATACACATTCAAAACCCGGACCGGTGAAATATCAGTCCACGCCGAAGATTTCACAC
TCCTCTCCAAATCACTGCGTCCCATACCCGTCGCCAAAGAAAAAGAGGTAGAGGGCGAGAAAGTGGTCTTCGACGCCTTC
TCCGACCGTGAGCTCCGATACCGCCAGCGCTATGTTGACCTCATCGTCAACCCCGAAGTCCGCGAAACCTTCATCAAAAG
AAGCGCCATCGTCTCACACATGCGCAGCTTCTTCACAGCCAAAGGGTGGCTTGAGGTTGAAACCCCGATCCTGCAGCCCA
TCTACGGAGGAGCTGCCGCACGCCCCTTCACCACGCACCACAATGCGCTGGACATGGAGCTCTACCTCCGCATTGCCAAC
GAGCTCTACCTCAAACGCCTCATTGTAGGCGGGTTTGAAGGAGTGTTTGAGTTCGCCAAAGATTTCCGCAACGAAGGCAT
TGACCGCTTCCACAACCCCGAATTCACCCAGGTGGAACTCTATGTGGCCTACAAAGACTATAACTGGATGATGGAGCTTG
TCGAACAGCTCTTCCACCAGACCGCCCTTGCCGTCAACGGGAGCGACACCACATCATTTCTGGGCAATGAAATCAGCCTC
AAGCCACCCTTCAGGCGCATCACCATTGCCGATTCAATCAAAGAATACACCGGCGCGGATATTGAAGGAAAAAGCGAGCA
GGAACTCCGCAACACGGCAAAGGACCTCGGCCTGGAACTCGACCCGAAAATCGGCCCCGGCAAAATCATTGATGAAATTT
TCGGTGAGTTTGTTGAACCCAAACTGATTCAGCCAACCTTCATCACCGACTACCCGACAGAAATGTCGCCCCTGGCCAAA
CCACACCGCGAAAAAGAAGGTCTGGTAGAGCGCTTCGAGCTGATTGCAGGCGGCAAAGAGATATGCAACTCCTTCTCCGA
ACTCAACGACCCGGTCGTGCAGCGCCAGCGGCTTGAAGAGCAGGCCGGCCTCCGCCAGCGCGGAGACGATGAGGCCATGA
TTGTTGACGAAGACTTCCTCAGAGCCCTTGAATACGGCATGCCCCCTACGGCAGGCCTCGGCATCGGCGTCGACCGCCTC
GTCATGCTGCTCACAGGAGAAGACTCAATCCGCGATGTCATCTTCTTCCCGCACATGAAGCCGGAATAA

Protein sequence :
MQQEHEQQISLNDQMQRRLDERTHLMESGINPYPCEFAVTAHSRDIIETFQEEAKTPVSVAGRIMAIRKMGKASFFHIQD
AKGRIQVYLKKDEVGETSYNTFKLLDIGDIAGVKGYTFKTRTGEISVHAEDFTLLSKSLRPIPVAKEKEVEGEKVVFDAF
SDRELRYRQRYVDLIVNPEVRETFIKRSAIVSHMRSFFTAKGWLEVETPILQPIYGGAAARPFTTHHNALDMELYLRIAN
ELYLKRLIVGGFEGVFEFAKDFRNEGIDRFHNPEFTQVELYVAYKDYNWMMELVEQLFHQTALAVNGSDTTSFLGNEISL
KPPFRRITIADSIKEYTGADIEGKSEQELRNTAKDLGLELDPKIGPGKIIDEIFGEFVEPKLIQPTFITDYPTEMSPLAK
PHREKEGLVERFELIAGGKEICNSFSELNDPVVQRQRLEEQAGLRQRGDDEAMIVDEDFLRALEYGMPPTAGLGIGVDRL
VMLLTGEDSIRDVIFFPHMKPE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-101 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001130215.1 lysyl-tRNA synthetase VFG1668 Protein 6e-102 46