Gene Information

Name : Cvib_0404 (Cvib_0404)
Accession : YP_001129928.1
Strain : Chlorobium phaeovibrioides DSM 265
Genome accession: NC_009337
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 413671 - 414414 bp
Length : 744 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAGGCAGTCATTCTTATACCCGCCAGGCTTGAGTCAAGCCGTCTTGAGCGGAAAATGCTTGCTGATCTTGAGGGGGA
GCCCCTCATTGTGCGCACATGGCGTCAGGCGATGCGTTCCACGCTTGCTGAACGGGTGGTTGTGGCTACCGACAGCCGCG
ACATAGCCTCGGTACTTGAAGAGCGGGGTGCCGAAGTTGTGATGACCTCTCCCTCTGCAAGCTGCGGCACGGAGAGGATT
GCCGAGGCGGCACGGAACATTGAAGGAGATGTGTTCGTGAACCTGCAGGGCGATGAACCCCTCATCAGTCCCGATACCAT
TGATCTGGTTCTGAGTCCCTTTTTTGCTGCCGACCCTCCTGACTGTTCCACGCTTGTTTTTGCCCTGCGCCCGGATGAAC
GGGAGCAGATTGAGGATCCGCATATCGTTAAAGCTCTGCTTGACAGGAAAGGCAACGCGCTTTATTTTTCGCGCAGTCCG
GTTCCCTTTATGCGCAACAATACCCCTTCTCTTGTGTTCTACCGTCATGTGGGGATGTACGCGTTTGGACGGGATGTTCT
GCAGCAATTTGCGGCACTGCCTGTATCGATGCTTGAGGCGGCGGAGTCGCTTGAGCAGCTCCGGCTGCTGGAGAACGGGT
TCAGCATTCGCTGTGTGATTACCACTCTTGACCAGCCAGGCGTCAACACCGCTGAGGATCTTGAGCTGGTGCGTTCCATT
CTCAGGAAGGAGTCCCGCTCCTGA

Protein sequence :
MKAVILIPARLESSRLERKMLADLEGEPLIVRTWRQAMRSTLAERVVVATDSRDIASVLEERGAEVVMTSPSASCGTERI
AEAARNIEGDVFVNLQGDEPLISPDTIDLVLSPFFAADPPDCSTLVFALRPDEREQIEDPHIVKALLDRKGNALYFSRSP
VPFMRNNTPSLVFYRHVGMYAFGRDVLQQFAALPVSMLEAAESLEQLRLLENGFSIRCVITTLDQPGVNTAEDLELVRSI
LRKESRS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-37 41
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-37 41