Gene Information

Name : guaA (Cvib_1589)
Accession : YP_001131101.1
Strain : Chlorobium phaeovibrioides DSM 265
Genome accession: NC_009337
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1766844 - 1768385 bp
Length : 1542 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAATCTGTCCTGGTACTGGATTTCGGATCACAATACACACAGCTGATAGCCCGCCGCATACGCGAACTCGGCATCTA
TTCCGAAATCCTCCCCTACAGCACCACACCTGAAACCATTCGCGAGCACAACCCGAGAGCAATCATCCTTTCGGGAGGAC
CCACAAGCGTCTATGGTGATTCAGCCATTCTACCCCACCCCGGAATCTTCTCTCTCGGCCTCCCTATCCTCGGTATCTGC
TACGGCCTGCAGGCCATCGCAAACCATTTCGGCGGTGCAGTTGAAAGCTCCTCCAAGCAGGAGTTCGGCAGGGCTAAAAT
TCTGGTGGACCGTAGCGCAGATCATGAAAGCCTGCTCTTTGAGGGCTTTCCGGATTCCGATGTATGGATGAGCCACGGCG
ACAAGGTAACCCGCATGCCCGAAGGATTCCGCGTCACCGCAAGCAGCGGAAACTCTGAAATGTGCGCCATCGAGAGCTAT
GGAAGCAAAGCCGCCCTTAAAATATACGGACTCCAGTTCCACCCCGAGGTACAGCACTCCCTGTACGGAAAACAGCTGCT
CGGGAACTTCCTGTTGAACATTGCCGGAATCACTCCCGACTGGTCGTCAAAAAGCTTTATCGACCACCAGATAGAGGATA
TTCGCGAACGGGCAGGAAACAATACGGTCATCTGCGGCATCAGCGGCGGGGTCGACTCTACCGTGGCCGCAGTTCTCGTC
AGTAAAGCCATCGGCAAACAGCTGCACTGCGTTTTTGTTGATAACGGCCTCCTCCGCAAGAATGAAGCAGAAAAAGTCAT
GCAGTTCCTCAAGCCGCTGGGCCTGAAAGTGACCCTTGCCGATTCGCGCGACCTTTTCCTCACGCGGCTGAAAGGTGTAG
CCTCCCCTGAAAAAAAACGCAAGATCATAGGCCGCACTTTCATCCGTGTCTTTGAAGAGCACATCCACGAAGAGAAGTTT
CTCGTGCAGGGCACCCTCTACCCCGATGTGATTGAGAGCGTCAGCGTCAAAGGGCCGTCGGAAACAATCAAATCGCACCA
CAATGTTGGCGGACTGCCCAAGCGCATGAAGCTGAAGCTCATTGAGCCGCTGCGCGAACTGTTCAAAGACGAGGTCCGCG
CTGTAGGCCGCGAACTTGGCATAGCTGAAGATATTCTCATGCGCCACCCTTTCCCCGGCCCCGGCCTTGCGGTCAGGGTG
CTCGGATCGGTGAACCCCGAACGGGTTGAAATTCTGCAGAACGCTGACGAAATTTTTATTGAAGAGCTGAAGTCAAGTGG
CCTCTACCAGCAGGTATGGCAGGCCTTCTCAGTGCTTCTTCCTGTGCAGTCGGTTGGAGTGATGGGCGACAAACGCACCT
ATGAGAATGTGCTTGCGCTCCGCGCTGTAGAATCAACAGACGGCATGACTGCCGACTGGGCCCACCTGCCGCACGACTTC
CTTGCGAAGGTATCGAACCGCATCATCAACGAAGTCCGCGGCATCAACCGTGTTGCCTACGACATATCATCAAAGCCACC
GGCTACTATAGAGTGGGAATAG

Protein sequence :
MQSVLVLDFGSQYTQLIARRIRELGIYSEILPYSTTPETIREHNPRAIILSGGPTSVYGDSAILPHPGIFSLGLPILGIC
YGLQAIANHFGGAVESSSKQEFGRAKILVDRSADHESLLFEGFPDSDVWMSHGDKVTRMPEGFRVTASSGNSEMCAIESY
GSKAALKIYGLQFHPEVQHSLYGKQLLGNFLLNIAGITPDWSSKSFIDHQIEDIRERAGNNTVICGISGGVDSTVAAVLV
SKAIGKQLHCVFVDNGLLRKNEAEKVMQFLKPLGLKVTLADSRDLFLTRLKGVASPEKKRKIIGRTFIRVFEEHIHEEKF
LVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIAEDILMRHPFPGPGLAVRV
LGSVNPERVEILQNADEIFIEELKSSGLYQQVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESTDGMTADWAHLPHDF
LAKVSNRIINEVRGINRVAYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-132 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-132 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-132 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-125 51