Gene Information

Name : hemC (Cvib_1245)
Accession : YP_001130759.1
Strain : Chlorobium phaeovibrioides DSM 265
Genome accession: NC_009337
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1398025 - 1398966 bp
Length : 942 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGAAAAAACAGCTTATCATCGGTACCCGCTCCAGCCCGCTCGCCCTCTGGCAGGCAGAATACACCAAGGCTGAGCTTTC
CAGACACTTTCCAGACCTTGACATCACCCTCAAACTTGTCAAAACAACCGGTGATGTACTGCTGGACTCCCCGCTCTCCA
AAATTGGAGACATGGGGCTCTTCACCAAAGACATCGAGAAATTCCTGATTGCCAAAGAGATTGATCTTGCTGTCCACAGC
CTGAAGGATGTTCCAACTGCCACTCCCGAAGGGCTGATCATCAGTGCCTTCACTGAGCGGGAAGACACCCGTGATGTCAT
CATCTCGAAAAACGGTGTCAAAATGCTTGACCTGCCCAAGAACGCAAAAGTAGCAACCAGCTCGCTTCGCCGCATGTCGC
AGCTCAAAAGCCTCCGCCCCGATTTTGACATCAAAGACATCCGCGGCAACCTCAACACCCGTTTCCAGAAATTTGACGAA
GGTGAATTTGACGCCATGATGCTTGCCTACGCCGGCGTCTACCGCCTCAACTTCAGCGACCGCATTTCCGAAATCCTTCC
GCATGAAATCATGCTGCCGGCTGTCGGACAGGGAGCACTGGGCATTGAAACCCGTGTTGACGACGAACAGACAAGGGAAA
TCGTGAAGGTGATGAACCACAGCAACACCGAGTACTGCTGCAAAGCTGAACGCTCGCTGCTCCGCCACCTTCAGGGCGGC
TGCCAGATTCCCATCGGCTCCTACGCCTCGTTCAAGAACGGAACACTGCACCTGCTCGCATTTGTCGGTTCAGTGGACGG
AACCAAGGGCATCCGCAACGAAATCACCAAAACCGGACTCACTTCTCCTGCACAGGCTGAAGCCGCCGGCATTGAACTTG
CTGAAGAGCTGCTGAAACAGGGCGCAGAGGAAATCCTTTCGGAAATCCGCAAAACCTGCTGA

Protein sequence :
MKKQLIIGTRSSPLALWQAEYTKAELSRHFPDLDITLKLVKTTGDVLLDSPLSKIGDMGLFTKDIEKFLIAKEIDLAVHS
LKDVPTATPEGLIISAFTEREDTRDVIISKNGVKMLDLPKNAKVATSSLRRMSQLKSLRPDFDIKDIRGNLNTRFQKFDE
GEFDAMMLAYAGVYRLNFSDRISEILPHEIMLPAVGQGALGIETRVDDEQTREIVKVMNHSNTEYCCKAERSLLRHLQGG
CQIPIGSYASFKNGTLHLLAFVGSVDGTKGIRNEITKTGLTSPAQAEAAGIELAEELLKQGAEEILSEIRKTC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-58 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-58 49