Gene Information

Name : tpx (Cvib_1103)
Accession : YP_001130619.1
Strain : Chlorobium phaeovibrioides DSM 265
Genome accession: NC_009337
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : 1.11.1.5
Position : 1244163 - 1244663 bp
Length : 501 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCAACGATTACTCTTAAAGGAAACACAATCCAGACTGTTGGAACCCTTCCTGCCGTCGGCAGCGAAGCTCCTTTTTT
CTGCCTCGTCAAAACCGATCTTTCTGAAGCGGGCCCTGCGGATTTTGCGGGAAAAAGAATGGTGCTGAACATTTTTCCGA
GTCTCGATACTGCAGTATGTGCGGCATCGGTGAGGCGATTCAACAAGGAGGCATCTTCTTTTGACAATACCGTGGTGCTT
TGTATTTCTGCCGATCTTCCCTTCGCACACAAGCGCTTCTGTGAGGTTGAGGGTCTTGACGATGTGATCTCTCTTTCAGT
ATTCCGCTCGCCAGCCTTCGGCAGTGATTATGGGGTGAGCATAGCTGATGGTCCTCTCAGAGGGCTTCTGTCGCGTGCAG
TGGTCATTGTTGATGCGGACGGTCGCATTGCATATACCGAGCAGGTTCCGGAAATTGTTGAGGAGCCTGATTATGATGCT
GCTCTTGCAGCCCTTGCATAA

Protein sequence : 
MATITLKGNTIQTVGTLPAVGSEAPFFCLVKTDLSEAGPADFAGKRMVLNIFPSLDTAVCAASVRRFNKEASSFDNTVVL
CISADLPFAHKRFCEVEGLDDVISLSVFRSPAFGSDYGVSIADGPLRGLLSRAVVIVDADGRIAYTEQVPEIVEEPDYDA
ALAALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 5e-32 45
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 3e-32 45
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 4e-32 45
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 2e-32 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001130619.1 thiol peroxidase VFG0087 Protein 8e-33 45