Gene Information

Name : SpyM50332 (SpyM50332)
Accession : YP_001127924.1
Strain : Streptococcus pyogenes Manfredo
Genome accession: NC_009332
Putative virulence/resistance : Unknown
Product : aminotransferase AlaT
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0436
EC number : 2.6.1.2
Position : 369606 - 370820 bp
Length : 1215 bp
Strand : +
Note : broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor

DNA sequence :
ATGAAAATTATTGAAAAATCATCAAAATTAGAACATGTTGCCTATGATATTCGAGGGCCTGTTTTGGATGAAGCTAATCG
CATGATTGCGAGTGGTGAAAAAATTCTGCGTTTAAATACTGGCAATCCTGCTGCCTTTGGTTTTGAAGCACCAGATGAAG
TGATTCGTGATTTAATTGTCAACGCGAGGCTAAGTGAGGGCTATTCTGACAGTAAAGGGATTTTTTCAGCGCGTAAGGCT
ATCATGCAATATTGCCAACTCAAGGGCTTCCCAGATGTTGACATTGAAGATATTTATTTGGGAAATGGCGTGTCAGAGTT
GATATCCATGTCCCTTCAAGCTTTGCTAGATAATGGCGATGAAGTTTTAGTACCAATGCCGGATTATCCTTTATGGACGG
CTTGTGTGAGTCTTGGTGGAGGAAAAGCGGTCCATTATCTTTGTGATGAAGAAGCTGGTTGGTATCCTGATATTGCTGAT
ATCAAATCAAAAATCACGAGTCGTACCAAAGCTATTGTGGTCATCAATCCTAATAACCCAACAGGAGCTCTTTATCCTAA
GGAGATTTTAGAAGACATTGTTGCTTTGGCAAGAGAACACCAGCTGATTATTTTTGCCGATGAAATCTATGATCGTTTGG
TGATGGATGGTAAAGAGCATATTGCTATTGCAAGCTTGGCACCTGATGTTTTTTGTGTATCTATGAATGGCCTTTCCAAA
TCTCATCGTATTGCTGGTTTTCGTGTTGGATGGATGGTCTTATCAGGTCCTAAAGACCATGTTAAAGGTTACATTGAAGG
GTTGAACATGCTTGCCAATATGCGGTTATGCTCCAATGTTTTAGCCCAACAAGTTGTTCAAACTTCCTTAGGAGGCCATC
AATCAGTTGATGCACTGTTACTGCCAGGAGGGCGTATTTTTGAGCAACGTAATTTTATTTATGAAGCTATTAATGCTATC
CCTGGCTTATCGGCAGTTAAACCTGAAGCAGGTCTTTATTTATTTCCGAAAATTGATCGTCAGATGTATCGTATTGATGA
TGATGAAGAATTTGTCTTACAGTTATTAAAGCAAGAAAAAGTGATGTTGGTACATGGACGTGGTTTTAACTGGAAAGATC
CAGATCACTTCCGTATTGTTTACCTACCAAGTGTAGAAGAATTAGAAGATGTTCAAGAAAAGATTACACGTGTCTTATAC
CAGTATAGACGTTAA

Protein sequence :
MKIIEKSSKLEHVAYDIRGPVLDEANRMIASGEKILRLNTGNPAAFGFEAPDEVIRDLIVNARLSEGYSDSKGIFSARKA
IMQYCQLKGFPDVDIEDIYLGNGVSELISMSLQALLDNGDEVLVPMPDYPLWTACVSLGGGKAVHYLCDEEAGWYPDIAD
IKSKITSRTKAIVVINPNNPTGALYPKEILEDIVALAREHQLIIFADEIYDRLVMDGKEHIAIASLAPDVFCVSMNGLSK
SHRIAGFRVGWMVLSGPKDHVKGYIEGLNMLANMRLCSNVLAQQVVQTSLGGHQSVDALLLPGGRIFEQRNFIYEAINAI
PGLSAVKPEAGLYLFPKIDRQMYRIDDDEEFVLQLLKQEKVMLVHGRGFNWKDPDHFRIVYLPSVEELEDVQEKITRVLY
QYRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aspC YP_005682179.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-117 57
aspC YP_005684271.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-117 57
aspC YP_003784329.1 aspartate aminotransferase Not tested PiCp 7 Protein 2e-117 57
aspC YP_005686363.1 Aminotransferase AlaT Not tested PiCp 7 Protein 2e-117 57