Gene Information

Name : hasC1 (SpyM51826)
Accession : YP_001129338.1
Strain : Streptococcus pyogenes Manfredo
Genome accession: NC_009332
Putative virulence/resistance : Virulence
Product : UTP--glucose-1-phosphate uridylyltransferase 1
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1210
EC number : 2.7.7.9
Position : 1823999 - 1824913 bp
Length : 915 bp
Strand : +
Note : Similar to SpyM50172, 90.268% identity (90.268% ungapped) in 298 aa overlap

DNA sequence : 
ATGACCAAAGTCAGAAAAGCCATTATTCCTGCTGCAGGTCTAGGAACACGTTTTTTACCTGCTACCAAAGCTCTTGCCAA
AGAGATGTTGCCCATCGTTGATAAACCAACCATCCAGTTTATCGTCGAAGAAGCGCTAAAATCTGGCATCGAGGAAATCC
TTGTGGTGACCGGAAAAGCTAAACGCTCTATCGAGGACCATTTTGATTCAAACTTTGAATTAGAGTACAACCTCCAAGCT
AAGGGGAAAAATGAACTGTTGAAATTAGTGGATGAAACCACTGCCATTAACCTTCATTTTATCCGTCAAAGCCACCCAAG
AGGACTGGGAGATGCTGTCTTACAAGCCAAAGCCTTTGTGGGCAATGAACCCTTTGTGGTCATGCTTGGAGATGACTTAA
TGGACATTACAAATGCATCCGCTAAACCTCTCACCAAACAACTCATGGAGGACTATGACAAGATGCATGCATCCACTATC
GCTGTGATGAAAGTTCCTCATGAAGATGTGTCTAGCTATGGGGTTATCGCCCCTCAAGGCAAGGCTGTCAAGGGCCTTTA
CAGTGTAGACACCTTTGTTGAAAAACCACAACCAGAAGATGCGCCTAGTGATTTGGCTATTATTGGTCGTTACCTCCTAA
CCCCTGAAATTTTTGATATTTTGGAAAGACAGGTCCCTGGAGCAGGTAACGAAGTGCAACTCACAGATGCTATCGATACC
CTCAATAAAACTCAGCGTGTCTTTGCACGAGAATTTAAAGGCAATCGTTACGATGTTGGGGATAAATTTGGATTCATGAA
AACATCTATCGACTATGCCTTAGAACACCCACAGGTCAAAGAGGACTTGAAAAATTACATTATCAAACTAGGAAAAGCTT
TGGAAAAAAGTAAAGTACCAACACATTCAAAGTAA

Protein sequence : 
MTKVRKAIIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVEEALKSGIEEILVVTGKAKRSIEDHFDSNFELEYNLQA
KGKNELLKLVDETTAINLHFIRQSHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITNASAKPLTKQLMEDYDKMHASTI
AVMKVPHEDVSSYGVIAPQGKAVKGLYSVDTFVEKPQPEDAPSDLAIIGRYLLTPEIFDILERQVPGAGNEVQLTDAIDT
LNKTQRVFAREFKGNRYDVGDKFGFMKTSIDYALEHPQVKEDLKNYIIKLGKALEKSKVPTHSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0059 YP_300149.1 UTP-glucose-1-phosphate uridylyltransferase Not tested SCC15305cap Protein 2e-74 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
hasC1 YP_001129338.1 UTP--glucose-1-phosphate uridylyltransferase 1 VFG0964 Protein 9e-142 99