Gene Information

Name : SpyM50140 (SpyM50140)
Accession : YP_001127736.1
Strain : Streptococcus pyogenes Manfredo
Genome accession: NC_009332
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 157606 - 158745 bp
Length : 1140 bp
Strand : +
Note : -

DNA sequence :
ATGAGAGAAAATACGACCTTATTACATGGCTATACGGTTATTGATGAGTTTACAGGAGCAGCTTCAGTTCCCATCTATCA
GACTTCGACGTTCCACAATTCAGAACTGTATTGTCCTAGTCAAAAACATTTGTACACACGCTTTTCAAACCCAACGACTG
AAGCTTTAGAAGACGGGTTAGCCTGTTTAGAAAAAGCGACTTATGCGGTGGCTTATGCATCTGGTATGGCTGCTATTTCA
ACTGTTTTGATGCTCTTAAAAGCTGGAGATCATGTGATTTTCCCATTGGAGGTCTATGGAGGGACTTGTCAATTTGCGAC
AGCTATTTTACCCAATTATCAGATTGAAACAAGCTTTGTAGATATGGCTGATTTAGCAACAGTAAAAGCAAGTATCAGGC
CTAATACGCGTATGATTTATCTAGAGACACCGTCAAATCCGCTCTTGAAAATTTGTGATATTTCAGAGCTTGTGCAACTC
GCCAAAGCTTATGGTGTGCTAACTGTGGCTGATAATACCTTTATGACAAGTTTGTATCAAGAACCCTTAGCTATGGGTGT
GGATATTGTGGTAGAAAGTGTGACCAAATTTATCAATGGTCATAGTGATGTGGTAGCTGGTTTAGCTGCTACCAATAATG
AAGCTATCTACAACCAGCTCAAGCTTTTTCAAAAAAACTTTGGAGCAATTGTTGGGGTCGAAGACGCTTGGCTGATTCTT
CGTGGCATGAAAACTATGGGGATCCGTATGGAACAAGCGGTAAAAAATGCTCAGCAGCTCGCTAACTATTTAGCGAAGCA
CCCCAAAGTTCTTAAGGTACATTACCCTGGCTTAGACAGTCATCCTAATCACGATACCCACCTGCAACAAGCTAAGAATG
GTGGTGCTGTTTTATCCTTTGAGTTGGCTTCTAAGGAGGAGCTGATGACCTTTACCCATCGTATTCAGTTGCCGATTTTA
GCCGTTAGTCTAGGTGGAGTAGAGTCCATTTTGTCACATCCAGCAACGATGTCTCATGCTTGTTTATCGTCACAAGCGCG
GTTGGAACAAGGGGTTGTTGATGGTTTGCTGCGCTTGTCTTGTGGTGTTGAAAATATCGAAGACTTATTGGCCGATTTTG
AGCAAGCACTTGCTTTTTAA

Protein sequence :
MRENTTLLHGYTVIDEFTGAASVPIYQTSTFHNSELYCPSQKHLYTRFSNPTTEALEDGLACLEKATYAVAYASGMAAIS
TVLMLLKAGDHVIFPLEVYGGTCQFATAILPNYQIETSFVDMADLATVKASIRPNTRMIYLETPSNPLLKICDISELVQL
AKAYGVLTVADNTFMTSLYQEPLAMGVDIVVESVTKFINGHSDVVAGLAATNNEAIYNQLKLFQKNFGAIVGVEDAWLIL
RGMKTMGIRMEQAVKNAQQLANYLAKHPKVLKVHYPGLDSHPNHDTHLQQAKNGGAVLSFELASKEELMTFTHRIQLPIL
AVSLGGVESILSHPATMSHACLSSQARLEQGVVDGLLRLSCGVENIEDLLADFEQALAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-178 99
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-77 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-77 43