Gene Information

Name : purA (SpyM50131)
Accession : YP_001127727.1
Strain : Streptococcus pyogenes Manfredo
Genome accession: NC_009332
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 148391 - 149683 bp
Length : 1293 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGACATCTGTAGTTGTTGTTGGTACCCAGTGGGGTGACGAAGGTAAAGGTAAAATCACTGATTTCTTGTCAGCGGATGC
AGAAGTAATTGCTCGCTATCAAGGTGGTGATAATGCTGGTCATACGATCGTGATTGATGGTAAGAAGTTTAAACTTCACT
TGATCCCATCAGGAATTTTCTTCCCGCAAAAAATTTCCGTTATTGGTAATGGTGTTGTGGTCAACCCCAAATCTTTGGTC
AAAGAGTTGGCGTACCTGCATGATGAAGGAGTGACGACAGATAACCTTCGCATTTCAGACCGAGCTCATGTCATTTTACC
TTATCATATCCAGCTGGATCAACTGCAAGAAGATGCAAAAGGTGACAATAAAATCGGAACAACTATTAAAGGGATTGGTC
CAGCTTATATGGATAAAGCTGCTCGAGTTGGTATCCGTATCGCAGATTTACTGGATAAGGATATCTTTGCAGAGCGCCTA
CGCATTAATTTAGCTGAGAAAAACCGTTTATTTGAAAAAATGTATGACAGTACACCTCTTGATTTTGATGCTATTTTTGA
AGAATACTATGCTTACGGTCAAGAAATCAAGCAATATGTGACAGATACTTCTGTAATTTTAAATGATGCACTTGATGCCG
GTAAACGTGTTCTTTTTGAAGGTGCACAAGGGGTTATGCTTGATATTGACCAAGGAACGTACCCATTTGTAACGTCTTCA
AACCCAGTTGCTGGTGGTGTAACCATTGGTTCTGGTGTTGGCCCAAGTAAAATCAACAAAGTAGTTGGTGTCTGTAAAGC
CTACACAAGCCGTGTCGGTGATGGGCCATTCCCTACAGAACTCTTTGATGAAGTGGGTGAGCGCATTCGTGAAGTGGGTC
ATGAGTACGGTACGACAACAGGTCGTCCACGTCGCGTGGGTTGGTTTGATTCGGTTGTCATGCGCCACAGTCGTCGTGTA
TCAGGTATTACTAACCTCTCTCTGAATTCAATTGATGTTCTTTCAGGGCTTGATACGGTTAAGATTTGTGTGGCTTATGA
CCTTGATAGGAAACGTATTGACTATTACCCAGCAAGCCTTGAACAACTCAAACGTTGCAAACCAATCTATGAAGAATTAC
CAGGCTGGCAAGAGGACATCACGGGTGTTCGTAGTCTTGATGAGCTGCCTGAAAATGCCCGCAACTATGTCCGTCGTGTT
GGAGAATTGGTTGGCGTTCGCATTTCAACCTTCTCAGTTGGTCCAGGGCGTGAACAGACCAATATTCTTGAGTCGGTCTG
GGCATCTATCTAA

Protein sequence :
MTSVVVVGTQWGDEGKGKITDFLSADAEVIARYQGGDNAGHTIVIDGKKFKLHLIPSGIFFPQKISVIGNGVVVNPKSLV
KELAYLHDEGVTTDNLRISDRAHVILPYHIQLDQLQEDAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFAERL
RINLAEKNRLFEKMYDSTPLDFDAIFEEYYAYGQEIKQYVTDTSVILNDALDAGKRVLFEGAQGVMLDIDQGTYPFVTSS
NPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGPFPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRV
SGITNLSLNSIDVLSGLDTVKICVAYDLDRKRIDYYPASLEQLKRCKPIYEELPGWQEDITGVRSLDELPENARNYVRRV
GELVGVRISTFSVGPGREQTNILESVWASI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 0.0 99