Gene Information

Name : fhuC (SpyM51534)
Accession : YP_001129057.1
Strain : Streptococcus pyogenes Manfredo
Genome accession: NC_009332
Putative virulence/resistance : Virulence
Product : ferrichrome transport ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 1511164 - 1511946 bp
Length : 783 bp
Strand : +
Note : -

DNA sequence :

ATGACAACAATTAGTGCTGAAGACCTCACAATTGCCTATGAACAGCGTACCATCATCGATAAATTATCGTTTTATATTCC
TGAAGGTAAAATTACGACCATTATTGGCGCCAATGGCTGTGGGAAGTCTAGTTTATTAAAAGCACTGACAAGATTATTAC
CACCAAAACAGGGAGTTGTGTATTTAAATGGGCAAAACATTGCCACATTAGAAACTAAAGAGGTTGCTAAAAAACTAGCT
CTTTTACCTCAAGTTCAAGAAGCAACTAACGGCATAACTGTTTACGAATTGGTTTCTTACGGACGTTTTCCCCATCAATC
TTACTTTGGAAATCTTAGTCCAGCTGACAAAAAAGTCATTCATTGGGCTATGCAAGCCACCAATGTCATGGCCTATGCTG
ATCAACCTGTTGATGCTCTTTCTGGGGGGCAACGTCAAAGGGTTTGGCTTGCAATGGCATTAGCCCAAGGCACTGATACT
ATTTTTTTAGATGAGCCAACTACTTATTTAGATTTAAATCATCAACTAGAAATCCTAGAGCTCGTTAAATCCCTAAATAA
GGATGCCGGCAAGACTATTGTTATGGTTCTTCACGACCTCAATCTTTCAGCCCGCTATTCGGATCATCTGATTGCTATGA
AACATGGCAAGATCCATTATACTGGTACTATAGCAGATGTTATGACTTCACCTATCATTCAAGACATCTTCCAAATCAAA
CCGGTACTGGTTGATGATCCTATCCACAACTGTCCTATAGTGCTGACTTATCAGCTTCAATAA

Protein sequence :

MTTISAEDLTIAYEQRTIIDKLSFYIPEGKITTIIGANGCGKSSLLKALTRLLPPKQGVVYLNGQNIATLETKEVAKKLA
LLPQVQEATNGITVYELVSYGRFPHQSYFGNLSPADKKVIHWAMQATNVMAYADQPVDALSGGQRQRVWLAMALAQGTDT
IFLDEPTTYLDLNHQLEILELVKSLNKDAGKTIVMVLHDLNLSARYSDHLIAMKHGKIHYTGTIADVMTSPIIQDIFQIK
PVLVDDPIHNCPIVLTYQLQ

• Homologs from PAI DB

Gene	GenBank Accn	Product	Virulance or Resistance	PAI or REI	Alignment Type	E-val	Identity
fagC	YP_003782430.1	ABC transporter ATP-binding protein	Not tested	PiCp 1	Protein	5e-58	47
fagC	YP_005682397.1	ATP binding cytoplasmic membrane protein	Virulence	PiCp 1	Protein	5e-58	47
fagC	YP_005684488.1	ATP binding cytoplasmic membrane protein	Not tested	PiCp 1	Protein	5e-58	47
fagC	YP_005680307.1	ATP binding cytoplasmic membrane protein	Not tested	PiCp 1	Protein	5e-58	47
iusE	YP_005143742.1	iron ABC transporter ATP-binding protein	Virulence	Not named	Protein	1e-58	46
SPN23F_09560	YP_002510939.1	ferric siderophore ABC transporter ATP-binding protein	Virulence	PPI-1	Protein	6e-54	45
SP_1035	NP_345510.1	iron-compound ABC transporter ATP-binding protein	Not tested	PPI-1	Protein	6e-54	45
fecE	AAL08451.1	ATP-binding protein FecE	Virulence	SRL	Protein	2e-52	44
DIP0585	NP_938961.1	iron ABC transporter ATP-binding protein	Virulence	Not named	Protein	1e-50	44
ciuD	YP_005681255.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	9e-51	43
ciuD	YP_005683346.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	9e-51	43
ciuD	YP_003783391.1	iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	9e-51	43
ciuD	YP_005685432.1	Iron ABC transporter ATP-binding protein	Virulence	PiCp 4	Protein	9e-51	43

• Homologs from CARD and BacMet (resistance genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
fhuC	YP_001129057.1	ferrichrome transport ATP-binding protein	BAC0164	Protein	1e-52	44

• Homologs from VFDB (virulence genes)

Gene	GenBank Accn	Product	ID of source DB	Alignment Type	E-val	Identity
fhuC	YP_001129057.1	ferrichrome transport ATP-binding protein	VFG0925	Protein	5e-58	46
fhuC	YP_001129057.1	ferrichrome transport ATP-binding protein	VFG1042	Protein	1e-52	44