Gene Information

Name : GTNG_0746 (GTNG_0746)
Accession : YP_001124871.1
Strain : Geobacillus thermodenitrificans NG80-2
Genome accession: NC_009328
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 814530 - 815708 bp
Length : 1179 bp
Strand : +
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGGAACGGGAATGGTCGTTTTCGACGAAATTGCTCCATAACAAATGGAAAGTCGATCGACATACAGGGGCGGTGAGCGT
GCCGATCCAGCATGCATCCACGTTCCATCAGTTCGATTTCGACTCATTCGGCAAATACGACTACAGCCGCTCCGGCAATC
CGACGCGCGAGGCGCTTGAAGAAACGATTGCCGCATTGGAAGGCGGTGTGCGCGGGTTTGCATTTGCTTCTGGCATGGCT
GCCATTTCCACAGCATTTTTGCTCCTGTCAAAGGGCGACCATGTGCTCGTGACGGAAGATGTCTACGGCGGCACATACCG
GATGATTACCGAGGTGCTTAATCGCTTTGGTATCGAATATACGTTCGTTGACATGACGGACCTTGAAGCAGTGGCGGAAA
ACATCCGGCCGAACACAAAGGTCATTTATATGGAAACGCCGTCCAATCCGCTCTTAAAAGTGACCGACATTCGCGGTGTC
GTCAAGTTGGCGAAAGCGCATGGCTGTTTAACTTTTCTGGACAATACGTTCATGACCCCAGCGTTGCAGCGGCCGTTGGA
TCTCGGCGTCGATGTTGTGCTTCATAGTGCGACGAAGTTTTTAGCCGGCCATAGCGACGTCGTTGCCGGGTTGGCGGTCG
TAAAAGACGAGGAGCTCGGCAAACAGCTATACAAATTGCAAAACGCCTTTGGCGCTGTCCTTGGCGTCCAAGATGCTTGG
CTTGTGCTGCGCGGTGTAAAAACACTCCATGTCCGGCTGAAACAGTCGTCTGAATCAGCGGCCGCCCTTGCTGCCTATTT
GACGCGCCATCCCAAAGTAGAGGAAGTGTACTATCCAGGATTGTCGCACCACCCGGGCCATGCGATCCAGCGCAATCAAG
CGGCTGGGTTCGGCGCTGTGCTGTCGTTCCGCCTGGCGGATGAAGAAGCGGCCCGGACGTTCGTCCGAAACGTTCGCTTA
CCGGTGTTCGCCGTCAGTCTTGGCGCTGTTGAATCGATTTTATCGTATCCAGCGAAAATGTCACATGCCGCCATGCCGAA
AGACGAGCGGCTGCGACGCGGCATTACCGACGGACTGTTGCGGTTGAGCGTCGGGCTTGAGGATCTCAACGATTTGATCG
CCGATTTTGAGCAGGCGCTATCATTTGTCAACGAGCGCTCGTCGATTCCGGCGCGATGA

Protein sequence :
MEREWSFSTKLLHNKWKVDRHTGAVSVPIQHASTFHQFDFDSFGKYDYSRSGNPTREALEETIAALEGGVRGFAFASGMA
AISTAFLLLSKGDHVLVTEDVYGGTYRMITEVLNRFGIEYTFVDMTDLEAVAENIRPNTKVIYMETPSNPLLKVTDIRGV
VKLAKAHGCLTFLDNTFMTPALQRPLDLGVDVVLHSATKFLAGHSDVVAGLAVVKDEELGKQLYKLQNAFGAVLGVQDAW
LVLRGVKTLHVRLKQSSESAAALAAYLTRHPKVEEVYYPGLSHHPGHAIQRNQAAGFGAVLSFRLADEEAARTFVRNVRL
PVFAVSLGAVESILSYPAKMSHAAMPKDERLRRGITDGLLRLSVGLEDLNDLIADFEQALSFVNERSSIPAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-90 54
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-85 50
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-84 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GTNG_0746 YP_001124871.1 cystathionine beta-lyase BAC0207 Protein 3e-65 42