Gene Information

Name : GTNG_0745 (GTNG_0745)
Accession : YP_001124870.1
Strain : Geobacillus thermodenitrificans NG80-2
Genome accession: NC_009328
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 813423 - 814526 bp
Length : 1104 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGAAGAAACTGGAGACATTGTTGGCGCAAATTGGCAATCGGAGCGAAACGGTGACGGGGACGGTCAACCCGCCGGTTTA
TTTTTCCACCGCCTACCGCCATGCCGGCATTGGAGAGTCCACCGGGTTTGACTACATCCGCACCGGCAATCCGACGCGCA
AAATCGTCGAAGAGGCGATCGCGAGGCTTGAAGGTGGTGACCAAGGCTATGCGTTCAGTTCCGGCATGGCCGCCATTCAG
ACAGTGCTCGCCTTGTTTGAGAGCGGAGACGAGTTTCTCGTATCGGCCGACCTTTACGGCGGCACGTACCGACTGTTTGA
GCGCGGCTGGCGTAAATACGGCCTCGGATTTCATTACGTTGATTTTGCTGATTTGGATGCCGTGGAAGAAAAAATCACGG
AACGGACAAAAGCAATCTTTTTGGAAACTCCAACAAACCCGCTTATGCATGAGACCGATATCCGCGCCGTCTCAGAGCTC
GCTAGGCGGTATGGGCTTTTACTGATCGTTGACAACACGTTTTATACGCCAGTGCTTCAACGCCCGATCGAACAAGGGGC
TGATATTGTCATCCATAGCGCCACGAAATATTTAGGCGGCCATAACGACGTCTTAGCTGGTCTAGTTGTTGCTAAGGGCG
AAGAGCTCTGTCAGCGCTTGGCGGAGTACCATAACGCCATCGGCGCCGTTTTGTCGCCGTTTGATTCATGGCTGTTGATT
CGCGGGATGAAAACGTTGGCGCTGCGGATGCGCCAGCATGAAGAAAACGCCAAGCGCATCTGCTCCTTTTTGCGTGAACA
CGAAGAGGTCACTGATGTGCTATACCCGGGAAGAGGGGGAATGTTGTCGTTCCGGATTGCCGATGAAAAATGGGTGAACG
GTTTTTTGCGATGTTTGCGTCTCATTACGTTCGCGGAAAGCCTAGGCGGGGTCGAAAGCTTTATCACGTATCCGGCGACG
CAGACGCACGCTGATATTCCGGAAGAAATCCGCATCCAAAACGGTGTTTGCAACCGTCTACTCCGTTTCTCGGTCGGTAT
CGAGCATGCCGACGATTTGATCGCTGATTTAGCGCAGGCATTGAAAAACATGAAAGAGGTGTGA

Protein sequence :
MKKLETLLAQIGNRSETVTGTVNPPVYFSTAYRHAGIGESTGFDYIRTGNPTRKIVEEAIARLEGGDQGYAFSSGMAAIQ
TVLALFESGDEFLVSADLYGGTYRLFERGWRKYGLGFHYVDFADLDAVEEKITERTKAIFLETPTNPLMHETDIRAVSEL
ARRYGLLLIVDNTFYTPVLQRPIEQGADIVIHSATKYLGGHNDVLAGLVVAKGEELCQRLAEYHNAIGAVLSPFDSWLLI
RGMKTLALRMRQHEENAKRICSFLREHEEVTDVLYPGRGGMLSFRIADEKWVNGFLRCLRLITFAESLGGVESFITYPAT
QTHADIPEEIRIQNGVCNRLLRFSVGIEHADDLIADLAQALKNMKEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-68 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-69 43