Gene Information

Name : thiC (GTNG_0346)
Accession : YP_001124473.1
Strain : Geobacillus thermodenitrificans NG80-2
Genome accession: NC_009328
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 393917 - 395608 bp
Length : 1692 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGGAAAACATTCGCTCGTTTATGTCATTTCCAGCCAGCCGGAAAGTGTACGTCGAAGGATCACGGCCGGACGTGCGCGT
GCCGATGAGAGAAATCGCGTTATCACCGACGAAGACACCGCAAGGAGAGGTGGAAAACAAACCGGTGCGCGTCTATGACA
CAACCGGTCCATACACAGATCCTGATTTTGAGCCGAATGTAGAAAAAGGATTGCCGCTTCTTCGCCGCAACTGGATTGTT
GAGCGAGGCGATGTCGAAGAAACGGAGCCACAGTCCACCGCCGGCCGTGCGGCGTCGCTTCCGTTTGCACGACGTCCGCT
GCGGGCGAAGCCGGGGAAAGTGGTCACGCAAATGCATTACGCCAAAAAAGGAATCATTACACCGGAAATGGAATTTGTCG
CGATTCGCGAACAAATCGACCCGGAAATCGTCCGCCAGGAGGTTGCCGCTGGCCGAGCGATCATCCCTTCGAATATTAAT
CATCCAGAAAGCGAACCGATGATCATCGGCCGCCGTTTTCATGTAAAAATTAACGCCAACATCGGCAACTCGGCTGTTTC
TTCCTCGATTGAGAATGAAGTGGAAAAACTGCTGTGGGCGGTACGCTGGGGTGCTGATACGGTGATGGATTTGTCGACCG
GCAAACAAATTCACGAAACGCGTGAATACATTATCCGCAATTCGCCAGTTCCAATCGGAACAGTGCCGATTTATCAGGCG
CTTGAGAAAGTAGGCGGCGTACCAGAGAAGTTGACATGGGACGTGTACCGCGAGACATTGATTGAGCAGGCTGAACAAGG
GGTTGACTACATGACGATCCACGCTGGTGTGCGGCTTCATTACATTCCGCTCACCGTCAATCGGACGACCGGCATCGTCT
CACGTGGCGGCTCAATCATCGCGCAATGGTGTTTGGCCCACCATGAAGAAAACTTCTTATATACGCATTTTGAAGAAATA
TGCGAGATTTTAAAACAATACGATGTTGCCATTTCGCTTGGTGACGGCTTGCGCCCGGGGTCCATTGCTGATGCAAACGA
CGAGGCACAGTTTGCTGAACTTGAGACGCTCGGTGAGCTGACGAAAATCGCTTGGGAGCATGACGTGCAAGTCATGATTG
AAGGACCGGGGCATATTCCGATGCAGAAAATCCGCGAAAACGTCGAGCGAGAACAAGAGCTTTGTCATGGTGCACCGTTT
TATACGTTAGGGCCGCTTGTCACCGACATTGCGCCGGGATACGACCACATCACGTCGGCGATTGGCGCCGCGATCATCGG
TGCCTACGGGACGTCCATGCTTTGCTATGTGACGCCGAAAGAACATTTAGGGTTACCAAATAAAGAGGATGTGCGCGTCG
GGGTCGTTACATATAAAATCGCCGCCCACGCCGCCGATTTGGCGAAAGGTCACCCAGCCGCCCAGCAGCGCGACGATGCG
CTCTCGAAAGCGCGCTTTGAGTTTCGCTGGAATGACCAGTTCAACTTATCGCTCGATCCGGAGCGGGCTCGCGAGTATCA
TGATGAAACATTGCCGGCTGAGGCGGCGAAAACCGCTCATTTTTGCTCGATGTGCGGGCCGAAATTTTGCTCGATGAACA
TCTCACACGAGCTGCAACGGAAAATCAAAGAAGAAGGAATGAAAGAAAAGGCGAACGAATTTGTGCGCGGCGGTTCATCG
CTGTATCGGTAA

Protein sequence :
MENIRSFMSFPASRKVYVEGSRPDVRVPMREIALSPTKTPQGEVENKPVRVYDTTGPYTDPDFEPNVEKGLPLLRRNWIV
ERGDVEETEPQSTAGRAASLPFARRPLRAKPGKVVTQMHYAKKGIITPEMEFVAIREQIDPEIVRQEVAAGRAIIPSNIN
HPESEPMIIGRRFHVKINANIGNSAVSSSIENEVEKLLWAVRWGADTVMDLSTGKQIHETREYIIRNSPVPIGTVPIYQA
LEKVGGVPEKLTWDVYRETLIEQAEQGVDYMTIHAGVRLHYIPLTVNRTTGIVSRGGSIIAQWCLAHHEENFLYTHFEEI
CEILKQYDVAISLGDGLRPGSIADANDEAQFAELETLGELTKIAWEHDVQVMIEGPGHIPMQKIRENVEREQELCHGAPF
YTLGPLVTDIAPGYDHITSAIGAAIIGAYGTSMLCYVTPKEHLGLPNKEDVRVGVVTYKIAAHAADLAKGHPAAQQRDDA
LSKARFEFRWNDQFNLSLDPERAREYHDETLPAEAAKTAHFCSMCGPKFCSMNISHELQRKIKEEGMKEKANEFVRGGSS
LYR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 67
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 67
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 66